[{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Celldex Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Celldex Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Celldex Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Celldex Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Celldex Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Celldex Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Celldex Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Celldex Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Celldex Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Celldex Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Public Offering","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Celldex Therapeutics \/ Jefferies","highestDevelopmentStatusID":"8","companyTruncated":"Celldex Therapeutics \/ Jefferies"},{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Public Offering","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Celldex Therapeutics \/ Jefferies","highestDevelopmentStatusID":"8","companyTruncated":"Celldex Therapeutics \/ Jefferies"},{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase III","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Celldex Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Celldex Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Celldex Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Barzolvolimab","moa":"c-KIT receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Celldex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Celldex Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Celldex Therapeutics \/ Inapplicable"}]

Find Dermatology Clinical Drug Pipeline Developments & Deals by Celldex Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : CDX-0159 (barzolvolimab) is a KIT inhibitor humanized monoclonal antibody. It is being evaluated for the treatment of patients with atopic dermatitis.

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          December 19, 2024

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : CDX-0159 (barzolvolimab) is a KIT inhibitor humanized monoclonal antibody. It is being evaluated for the treatment of patients with chronic inducible urticaria.

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          October 26, 2024

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : CDX-0159 (barzolvolimab) is a KIT inhibitor humanized monoclonal antibody. It is being evaluated for the treatment of patients with chronic inducible urticaria.

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          July 29, 2024

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : CDX-0159 (barzolvolimab) is an antibody that specifically binds the receptor tyrosine kinase KIT. It is being evaluated for the treatment of prurigo nodularis.

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          May 15, 2024

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : CDX-0159 (barzolvolimab) is a humanized monoclonal antibody targeting receptor tyrosine kinase KIT. It’s being evaluated for chronic inducible urticaria and symptomatic dermographism.

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 17, 2024

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : The proceeds will continue development of Celldex's product, including current and future development of CDX-0159 (barzolvolimab), growing its bispecific antibody platform and clinical candidates, funding ongoing efforts to develop additional clinical pi...

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          July 11, 2023

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Jefferies

                          Deal Size : Undisclosed

                          Deal Type : Public Offering

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                          07

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : The proceeds will continue development of Celldex's product, including current and future development of CDX-0159 (barzolvolimab), growing its bispecific antibody platform and clinical candidates, funding ongoing efforts to develop additional clinical pi...

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          July 11, 2023

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Jefferies

                          Deal Size : $200.5 million

                          Deal Type : Public Offering

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                          08

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : CDX-0159 (barzolvolimab) is a humanized monoclonal antibody that specifically binds the receptor tyrosine kinase KIT with high specificity and potently inhibits its activity. KIT signaling controls the differentiation, tissue recruitment, survival and ac...

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 02, 2023

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          DIA 2025
                          Not Confirmed
                          DIA 2025
                          Not Confirmed

                          Details : CDX-0159 (barzolvolimab) is a humanized monoclonal antibody that binds the receptor tyrosine kinase KIT with high specificity and potently inhibits its activity.

                          Product Name : CDX-0159

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          June 12, 2022

                          Lead Product(s) : Barzolvolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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