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Find Clinical Drug Pipeline Developments & Deals by CARsgen Therapeutics
CT053 (zevorcabtagene autoleucel) is an autologous BCMA-targeted CAR T-cell product, which is being evaluated for the treatment of relapsed or refractory multiple myeloma.
CT011 is an autologous CAR T-cell product candidate against GPC3. It is currently being evaluated for the treatment of patients with GPC3-positive stage Ⅲa hepatocellular carcinoma.
CT071 is a GPRC5D inhibitor cell and gene therapy drug candidate, which is currently being evaluated for the treatment of relapsed/refractory multiple myeloma.
The collaboration aims to investigate CARsgen's investigational CT041 (satricabtagene autoleucel), a Claudin18.2 CAR T-cell product candidate, in combination with Moderna’s investigational Claudin18.2 mRNA cancer vaccine.
Lead Product(s):
Satricabtagene Autoleucel,Claudin18.2 mRNA Vaccine
CT041 is an autologous CAR T-cell product candidate against the protein CLDN18.2 that has the potential to be the first-in-class treatment for positive solid tumors with a primary focus on gastric cancer/gastroesophageal junction cancer (GC/GEJ) and PC.
AB011 is a humanized CLDN18.2 monoclonal antibody (mAb) product that has received an investigational new drug (IND) approval from the National Medical Products Administration (NMPA) for the treatment of CLDN18.2 positive solid tumors.
CT041 is an autologous CAR T-cell product candidate against the protein CLDN18.2 that has the potential to be the first-in-class treatment for positive solid tumors with a primary focus on gastric cancer/gastroesophageal junction cancer (GC/GEJ) and PC.
Under the agreement, Roche will be responsible for operation and conduct of the trial while both companies co-share the costs of AB011 treatment arms in study. The co-funded study of AB011 in combination with atezolizumab will be conducted as part of Roche's Morpheus Platform.
Lead Product(s):
Humanized Claudin18.2 Monoclonal Antibody,Atezolizumab
AB011 is a humanized Claudin18.2 mAb product that has received an IND approval from the NMPA for the treatment of Claudin18.2 positive solid tumors. AB011 is being investigated for the treatment of Claudin18.2 positive solid tumors in China.
Lead Product(s):
Humanized Claudin18.2 Monoclonal Antibody
Zevor-cel (CT053) is a fully human, autologous BCMA CAR T-cell product candidate for the treatment of R/R MM. Results from the LUMMICAR-1 study show that zevor-cel, demonstrated strong and durable efficacy in patients with relapsed/refractory multiple myeloma.
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