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mRNA","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Oncotelic Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Oncotelic Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"Oncotelic Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Oncotelic Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2024","type":"Inapplicable","leadProduct":"Trabedersen","moa":"||Transforming growth factor beta-2 mRNA","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Oncotelic Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Oncotelic Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"Oncotelic Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Mabxience","sponsor":"Zentiva","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SPAIN","productType":"Antibody, Unconjugated","year":"2021","type":"Collaboration","leadProduct":"Bevacizumab","moa":"||Vascular endothelial growth factor A","graph1":"Oncology","graph2":"Approved FDF","graph3":"Mabxience","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Mabxience \/ Zentiva","highestDevelopmentStatusID":"15","companyTruncated":"Mabxience \/ Zentiva"},{"orgOrder":0,"company":"Sapience Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2024","type":"Inapplicable","leadProduct":"Irinotecan","moa":"||Wnt\/beta-catenin","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Sapience Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Injection","sponsorNew":"Sapience Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sapience Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Sapience Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2024","type":"Inapplicable","leadProduct":"Irinotecan","moa":"||Wnt\/beta-catenin","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Sapience Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sapience Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sapience Therapeutics \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals for Calcium Folinate

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                          01

                          Details : Leucovorin is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 11, 2017

                          Lead Product(s) : Calcium Folinate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          02

                          Lead Product(s) : Calcium Folinate

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Leucovorin is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Pancreatic Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 12, 2010

                          Lead Product(s) : Calcium Folinate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          03

                          PREP
                          Not Confirmed
                          PREP
                          Not Confirmed

                          Details : The exploratory clinical study of systemic DNase I in combination with FOLFIRINOX for the first line treatment of unresectable, locally advanced or metastatic pancreatic cancer.

                          Product Name : XBIO-015

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          July 08, 2025

                          Lead Product(s) : Deoxyribonuclease I,Calcium Folinate,Fluorouracil

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : PeriNess

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Charite University, Berlin, Germany

                          Country arrow
                          PREP
                          Not Confirmed

                          Charite University, Berlin, Germany

                          Country arrow
                          PREP
                          Not Confirmed

                          Details : Folinic Acid is a Other Small Molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Colorectal Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 04, 2025

                          Lead Product(s) : Calcium Folinate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Merck Group | Guardant Health

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ECOG-ACRIN Cancer Research Group

                          Country arrow
                          PREP
                          Not Confirmed

                          ECOG-ACRIN Cancer Research Group

                          Country arrow
                          PREP
                          Not Confirmed

                          Details : Leucovorin is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Stomach Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 03, 2025

                          Lead Product(s) : Calcium Folinate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : National Cancer Institute

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          PREP
                          Not Confirmed
                          PREP
                          Not Confirmed

                          Details : PCM-075 (onvansertib) is a PLK-1 inhibitor, which is being evaluated in combination with Folfiri & Bevacizumab for the treatment of second-line RAS-mutated metastatic colorectal cancer.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 15, 2025

                          Lead Product(s) : Onvansertib,Bevacizumab,Calcium Folinate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          PREP
                          Not Confirmed
                          PREP
                          Not Confirmed

                          Details : Imfinzi (durvalumab) is a PD-L1 Inhibitor antibody, which is currently being evaluated for early-stage and locally advanced (Stages II, III, IVA) gastric and gastroesophageal junction (GEJ) cancers.

                          Product Name : Imfinzi

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          March 07, 2025

                          Lead Product(s) : Durvalumab,Fluorouracil,Calcium Folinate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          PREP
                          Not Confirmed
                          PREP
                          Not Confirmed

                          Details : ST316 is a first-in-class peptide antagonist of the interaction between β-catenin and its co-activator, BCL9. It is being evaluated for the treatment of familial adenomatous polyposis.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          December 19, 2024

                          Lead Product(s) : ST316,Irinotecan Hydrochloride,Calcium Folinate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          PREP
                          Not Confirmed
                          PREP
                          Not Confirmed

                          Details : CEND-1 (certepetide) is an Alpha-V integrin inhibitor peptide candidiate which is being evaluated in combination with chemotherapy for the treatment of pancreatic cancer.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          December 10, 2024

                          Lead Product(s) : Certepetide,Calcium Folinate,Panitumumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Cancer Research Antwerp

                          Country arrow
                          PREP
                          Not Confirmed

                          Cancer Research Antwerp

                          Country arrow
                          PREP
                          Not Confirmed

                          Details : Leucovorin is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Pancreatic Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 15, 2024

                          Lead Product(s) : Calcium Folinate

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Sponsor : Kom Op Tegen Kanker | Naslund Medical AB | Varian Medical Systems

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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