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Find Clinical Drug Pipeline Developments & Deals for BCG Vaccine
The proceeds will also be used to fund company's clinical trials expanding N-803 (Anktiva), an interleukin-15 superagonist fusion protein, being developed for indications into multiple solid tumors, including BCG-unresponsive non-muscle invasive bladder cancer.
Anktiva (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex plus Bacillus Calmette-Guérin (BCG) for the treatment of BCG-unresponsive non-muscle-invasive bladder cancer carcinoma in situ (CIS) with or without Ta or T1 disease.
Anktiva (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex plus Bacillus Calmette-Guérin (BCG) for the treatment of BCG-unresponsive non-muscle-invasive bladder cancer carcinoma in situ (CIS) with or without Ta or T1 disease.
The financing will fund company's ongoing business operations and pre-commercialization efforts as it continues to drive toward a potential regulatory approval of Anktiva (N-803), a novel IL-15 superagonist, plus BCG for BCG-unresponsive non-muscle invasive bladder cancer.
Anktiva™ (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex and has received breakthrough therapy and fast track designations from the U.S. FDA for BCG-unresponsive CIS non-muscle invasive bladder cancer.
The vaccine, TUBERVAC-rBCG can be administered to children and adults both. Once DCGI approves Serum Institute's TB vaccine, the National Technical Advisory Group on Immunisation (NTAGI) will decide on its introduction.
Positive QUILT 3.032 trial for Anktiva (N-803) results in 71% of BCG-unresponsive NMIBC patients who had failed on previous therapies showed complete response with duration of 26.6 months; cystectomy avoidance rate of 91% and 100% bladder cancer overall survival at 24 months.
Data demonstrate for BCG-unresponsive bladder cancer patients who were treated with BCG plus N-803 (Anktiva) and the doubling of historic overall survival rates in patients with advanced pancreatic cancer who were treated with the Nant Cancer Vaccine.
Anktiva™ (N-803) is an IL-15RαFc Superagonist, a proprietary therapeutic cytokine designed to induce expansion of native NK and CD8+ T-cells without concurrent stimulation of T-regulatory cells
All data for QUILT-3.032, which is studying VesAnktiva plus BCG in subjects with BCG-unresponsive non-muscle invasive bladder cancer carcinoma in situ, have been locked and analyzed. The results continue to demonstrate a clinically meaningful benefit that is sustained.
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