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Brown, MD MPH"},{"orgOrder":0,"company":"Astellas Pharma","sponsor":"Daniel Burdick, MD","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"JAPAN","productType":"Miscellaneous","year":"2014","type":"Inapplicable","leadProduct":"Mirabegron","moa":"Beta-3 adrenergic receptor","graph1":"Neurology","graph2":"Phase IV","graph3":"Astellas Pharma","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Astellas Pharma \/ Daniel Burdick, MD","highestDevelopmentStatusID":"11","companyTruncated":"Astellas Pharma \/ Daniel Burdick, MD"},{"orgOrder":0,"company":"Astellas Pharma","sponsor":"Norman Muirhead","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"JAPAN","productType":"Antibiotic","year":"2011","type":"Inapplicable","leadProduct":"Tacrolimus","moa":"FK506-binding protein 1A","graph1":"Undisclosed","graph2":"Phase IV","graph3":"Astellas 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                            Lead Product(s) : ASP2957

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Study of ASP2957 in Male Patients with X-linked Myotubular Myopathy Who Need Ventilators

                            Details : ASP2957 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of X-Linked Myotubular Myopathy.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            July 08, 2025

                            Lead Product(s) : ASP2957

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

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                            Lead Product(s) : ASP2138

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Study of ASP2138 Before Surgery & Chemotherapy in Pancreatic Ductal Cancer Patients

                            Details : ASP2138 is a Antibody drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Carcinoma, Pancreatic Ductal.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            June 17, 2025

                            Lead Product(s) : ASP2138

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

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                            Lead Product(s) : ASP1893

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Study of ASP1893 in Adults With Advanced CLDN6-positive Solid Tumors

                            Details : ASP1893 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            November 08, 2024

                            Lead Product(s) : ASP1893

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

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                            04

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                            Lead Product(s) : ASP2016

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Study of ASP2016 in Adults Who Have Heart Disease Associated With Friedreich Ataxia

                            Details : ASP2016 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Friedreich Ataxia.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            July 03, 2024

                            Lead Product(s) : ASP2016

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Astellas Pharma

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                            Lead Product(s) : ASP2802

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Study to Find a Suitable Dose of ASP2802 in People With CD20-positive B-cell Lymphomas

                            Details : ASP2802 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Lymphoma, B-Cell.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            February 08, 2024

                            Lead Product(s) : ASP2802

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Astellas Pharma

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Mass General Brigham

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Astellas Announces Strategic Collaboration with Mass General Brigham

                            Details : The collaboration aims to advance translational research and accelerate early development of novel therapies including on oncology, rare disease, and cell and gene therapies.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 30, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Mass General Brigham

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Astellas Pharma

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                            Lead Product(s) : ES019

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Elpiscience

                            Deal Size : $1,737.0 million

                            Deal Type : Collaboration

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                            Elpiscience and Astellas Enter into Research Collaboration and License Agreement for Novel Bispecific Macropha...

                            Details : The collaboration aims to conduct early-stage research for novel bi-specific macrophage engagers, ES019, an anti-PD-L1/SIRPα bispecific antibody, and another program.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            December 27, 2023

                            Lead Product(s) : ES019

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Elpiscience

                            Deal Size : $1,737.0 million

                            Deal Type : Collaboration

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                            08

                            Astellas Pharma

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                            Lead Product(s) : Zolbetuximab,Capecitabine,Oxaliplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            China’s National Medical Products Administration Accepts Astellas’ Biologics License Application for Zolbe...

                            Details : IMAB362 (zolbetuximab) is an investigational, first-in-class chimeric IgG1 mAb that targets and binds to CLDN18.2 present on the cancer cell surface of gastric epithelial cells. It induces cancer cell death by activating ADCC and CDC immune system.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            July 31, 2023

                            Lead Product(s) : Zolbetuximab,Capecitabine,Oxaliplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Astellas Pharma

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                            Lead Product(s) : Zolbetuximab,Capecitabine,Oxaliplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Astellas Announces Positive Findings from Phase 3 GLOW Trial of Zolbetuximab during March ASCO Plenary Series

                            Details : IMAB362 (zolbetuximab) is an investigational, first-in-class chimeric IgG1 mAb that targets and binds to CLDN18.2 present on the cancer cell surface of gastric epithelial cells. It induces cancer cell death by activating ADCC and CDC immune system.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            March 22, 2023

                            Lead Product(s) : Zolbetuximab,Capecitabine,Oxaliplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Astellas Pharma

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                            Lead Product(s) : ASP1002

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Study of ASP1002 in Adults for Treatment of Solid Tumors

                            Details : ASP1002 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            February 09, 2023

                            Lead Product(s) : ASP1002

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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