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Find Clinical Drug Pipeline Developments & Deals by Armata Pharmaceuticals
The net proceeds will be used to advance the Company's lead therapeutic phage candidates, including AP‐PA02 and AP‐SA02, which target infections caused by Pseudomonas aeruginosa and Staphylococcus aureus, respectively.
AP-SA02 as an adjunct to best available antibiotic therapy and potential treatment for Staphylococcus aureus bacteremia. Initiation of the P2a portion of the study follows Data Review Committee (DRC) review of positive safety and tolerability data from the Phase 1b portion.
AP-PA02 is a therapeutic phage cocktail that targets the pathogen P. aeruginosa, to treat serious respiratory infections, with an emphasis on patients with cystic fibrosis and non-cystic fibrosis bronchiectasis.
Armata intends to use the net proceeds from this transaction to continue clinical development of AP-PA02 and AP-SA02. AP-PA02 targets the pathogen P. aeruginosa, to treat serious respiratory infections, with an emphasis on patients with CF and NCFB.
Armata is developing and advancing a broad pipeline of natural and synthetic phage candidates, including clinical candidate AP-PA02 for Pseudomonas aeruginosa, Staphylococcus aureus, and other pathogens.
AP-SA02 is a novel biologic product candidate comprising natural lytic phages that target the problematic pathogen, Staphylococcus aureus, and offers robust therapeutic attributes, including Potent antimicrobial activity.
In pre-clinical studies, AP-SA02 demonstrated potent antimicrobial activity against approximately 95% of S. aureus clinical isolates evaluated, including drug-resistant strains, and, we believe, due to its potency and biofilm activity.
Armata intends to use the net proceeds from this transaction to advance its clinical pipeline and strengthen its bacteriophage platform. The clinical pipeline is led by AP-PA02, currently under evaluation.
Company Announces FDA clearance of IND to initiate Phase 1b/2a clinical trial of AP-SA02 in Staphylococcus aureus bacteremia as an adjunct to best available antibiotic therapy.
The SWARM-P.a. study will the first FDA cleared Phase 1b/2a, controlled clinical trial to evaluate the safety and tolerability of inhaled AP-PA02 in subjects with cystic fibrosis and chronic pulmonary Pseudomonas aeruginosa infection.
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