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    [{"orgOrder":0,"company":"ABL Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"SOUTH KOREA","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"ABL301","moa":"IGF-1 receptor","graph1":"Undisclosed","graph2":"Phase I","graph3":"ABL Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ABL Bio \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"ABL Bio \/ Inapplicable"},{"orgOrder":0,"company":"ABL Bio","sponsor":"I-Mab Biopharma","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"Givastomig","moa":"||CLDN18.2","graph1":"Oncology","graph2":"Phase I","graph3":"ABL Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous 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    Find Clinical Drug Pipeline Developments & Deals by ABL Bio

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                            01

                            ABL Bio

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Undisclosed

                            Sponsor : GSK

                            Deal Size : $2,725.3 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            ABL Bio Licenses Brain Drug Platform to GSK for Neuro Diseases

                            Details : Under the licensing agreement, GSK will develop novel medicines for neurodegenerative diseases by utilizing ABL Bio's blood-brain barrier (BBB) shuttle platform, Grabody-B.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $49.6 million

                            April 06, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Undisclosed

                            Sponsor : GSK

                            Deal Size : $2,725.3 million

                            Deal Type : Licensing Agreement

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                            02

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                            Lead Product(s) : Givastomig,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : I-Mab Biopharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            I-Mab Announces Accelerated Givastomig Phase 1b Study Progress

                            Details : TJ033721 (givastomig) is a potential best-in-class, Claudin 18.2 (CLDN18.2) x 4-1BB bispecific antibody, targeting CLDN18.2-positive tumor cells.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 07, 2025

                            Lead Product(s) : Givastomig,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : I-Mab Biopharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Lead Product(s) : ABL103,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Merck & Co

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            ABL Bio Collaborates to Evaluate ABL103 with KEYTRUDA® For Solid Tumors

                            Details : The collaboration aims to evaluate ABL103 in combination with MSD's anti-PD-1 therapy, Keytruda (pembrolizumab) in patients with advanced or metastatic solid tumors.

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Undisclosed

                            April 10, 2024

                            Lead Product(s) : ABL103,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Merck & Co

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Biocytogen

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Biocytogen Collaborates With ABL Bio To Develop Bispecific Antibody-Drug Conjugates

                            Details : The collaboration aims to develop new bispecific antibody-drug conjugates using Biocytogen’s RenLite® mice platform that can produce fully human antibodies with diverse epitopes and high affinity.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            March 25, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Biocytogen

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Lead Product(s) : ABL103

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study With ABL103 in Subjects With Advanced or Metastatic Solid Tumors

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            November 13, 2023

                            Lead Product(s) : ABL103

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Lead Product(s) : TJ-L14B

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : I-Mab Biopharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            I-Mab and ABL Bio Announce Latest Updates of PD-L1 and 4-1BB Bispecific Antibody TJ-L14B/ABL503

                            Details : TJ-L14B/ABL503, is a differentiated PD-L1 x 4-1BB bispecific antibody, which is investigated in patients with progressive, locally advanced or metastatic solid tumors who are relapsed or refractory following prior lines of treatment.

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            October 10, 2023

                            Lead Product(s) : TJ-L14B

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : I-Mab Biopharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Recipient : Synaffix

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            ABL Bio Taps into Synaffix ADC Technology to Accelerate Development of Bispecific ADC Products

                            Details : Under the agreement, ABL Bio will be responsible for the research, development, and commercialization of bispecific ADCs, designed to overcome the limitations of conventional therapeutic ADCs that target only a single antigen on the targeted cancer cell.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            September 13, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Recipient : Synaffix

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            Lead Product(s) : ABL301

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            This is a Study to Evaluate the Safety, Tolerability, PK and PD of IV Administered ABL301 in Healthy Adult Par...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 07, 2023

                            Lead Product(s) : ABL301

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Lead Product(s) : ABL301

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Sanofi

                            Deal Size : $1,060.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            ABL Bio Enters Global Collaboration and License Agreement with SANOFI to Advance ABL301 for the Treatment of P...

                            Details : ABL and SANOFI to collaborate on the development of ABL301, a potential first-in-class bispecific antibody targeting alpha-synuclein and containing a proprietary brain shuttle, for alpha-synucleinopathies, including Parkinson's disease.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : $75.0 million

                            November 01, 2022

                            Lead Product(s) : ABL301

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Sanofi

                            Deal Size : $1,060.0 million

                            Deal Type : Collaboration

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                            Lead Product(s) : CTx-GBA1

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : Coave Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Coave Therapeutics and ABL Enter Into Strategic Collaboration to Develop Gene Therapy Manufacturing Processes ...

                            Details : Under the two-stage collaboration both companies will initially combine their complementary expertise to co-develop manufacturing technologies for AAV-based gene therapy products including CTx-GBA1.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 06, 2022

                            Lead Product(s) : CTx-GBA1

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : Coave Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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