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    [{"orgOrder":0,"company":"Indoco Remedies Limited","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"INDIA","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Xanthine oxidase","graph1":"Rheumatology","graph2":"Approved FDF","graph3":"Indoco Remedies Limited","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Indoco Remedies Limited \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Indoco Remedies Limited \/ Inapplicable"},{"orgOrder":0,"company":"InventisBio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"CHINA","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Undisclosed","graph1":"Rheumatology","graph2":"Phase II","graph3":"InventisBio","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Oral","sponsorNew":"InventisBio \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"InventisBio \/ Inapplicable"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Parexel","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Solute carrier family 22 member 12","graph1":"Nephrology","graph2":"Phase II","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral","sponsorNew":"AstraZeneca \/ Parexel","highestDevelopmentStatusID":"8","companyTruncated":"AstraZeneca \/ Parexel"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Parexel","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Solute carrier family 22 member 12","graph1":"Nephrology","graph2":"Phase II","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Capsule, Extended Release","sponsorNew":"AstraZeneca \/ Parexel","highestDevelopmentStatusID":"8","companyTruncated":"AstraZeneca \/ Parexel"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Parexel","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Solute carrier family 22 member 12","graph1":"Nephrology","graph2":"Phase II","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Capsule, Prolonged Release","sponsorNew":"AstraZeneca \/ Parexel","highestDevelopmentStatusID":"8","companyTruncated":"AstraZeneca \/ Parexel"},{"orgOrder":0,"company":"dr. M.J.N.L. Benders","sponsor":"ZonMw | University Medical Center Groningen | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | Radboud University Medical Center, Nijmegen | ACE Pharmaceuticals BV","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Xanthine dehydrogenase","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"dr. M.J.N.L. Benders","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Powder For Solution","sponsorNew":"dr. M.J.N.L. Benders \/ ZonMw | University Medical Center Groningen | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | Radboud University Medical Center, Nijmegen | ACE Pharmaceuticals BV","highestDevelopmentStatusID":"10","companyTruncated":"dr. M.J.N.L. Benders \/ ZonMw | University Medical Center Groningen | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | Radboud University Medical Center, Nijmegen | ACE Pharmaceuticals BV"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Solute carrier family 22 member 12","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase II","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"AstraZeneca \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"AstraZeneca \/ Inapplicable"},{"orgOrder":0,"company":"MD Anderson Cancer Center","sponsor":"Loxo Oncology Inc | Leukemia and Lymphoma Society","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Pirtobrutinib","moa":"||Tyrosine-protein kinase BTK","graph1":"Oncology","graph2":"Phase II","graph3":"MD Anderson Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"MD Anderson Cancer Center \/ Loxo Oncology Inc | Leukemia and Lymphoma Society","highestDevelopmentStatusID":"8","companyTruncated":"MD Anderson Cancer Center \/ Loxo Oncology Inc | Leukemia and Lymphoma Society"},{"orgOrder":0,"company":"Urica Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||URAT1","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Urica Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Urica Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Urica Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Arthrosi Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Urate anion exchanger 1 (URAT1)","graph1":"Undisclosed","graph2":"Phase I","graph3":"Arthrosi Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Arthrosi Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Arthrosi Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"InventisBio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CHINA","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||Undisclosed","graph1":"Undisclosed","graph2":"Phase I","graph3":"InventisBio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"InventisBio \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"InventisBio \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals for 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one

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    1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one

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                            01

                            Indoco Remedies Limited

                            India arrow
                            EPSC
                            Not Confirmed

                            Indoco Remedies Limited

                            India arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Allopurinol,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Indoco Remedies Gains USFDA Final Approval for Allopurinol Tablets USP 200 mg

                            Details : Zyloprim-Generic (allopurinol) is a xanthine oxidase inhibitor. It is indicated for the treatment of primary or secondary gout, leukemia, lymphoma and solid tumor malignancies.

                            Product Name : Zyloprim-Generic

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 23, 2025

                            Lead Product(s) : Allopurinol,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Urica Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Urica Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Dontinurad,Dotinurad,Allopurinol

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients with Hyperuricemia

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 28, 2023

                            Lead Product(s) : Dontinurad,Dotinurad,Allopurinol

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            InventisBio

                            China arrow
                            EPSC
                            Not Confirmed

                            InventisBio

                            China arrow
                            EPSC
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : D-0120,Allopurinol

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With Gout

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            December 27, 2022

                            Lead Product(s) : D-0120,Allopurinol

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            MD Anderson Cancer Center

                            Country arrow
                            EPSC
                            Not Confirmed

                            MD Anderson Cancer Center

                            Country arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Pirtobrutinib,Obinutuzumab,Venetoclax,Valacyclovir,Allopurinol

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Loxo Oncology Inc | Leukemia and Lymphoma Society

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-na...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 10, 2022

                            Lead Product(s) : Pirtobrutinib,Obinutuzumab,Venetoclax,Valacyclovir,Allopurinol

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Loxo Oncology Inc | Leukemia and Lymphoma Society

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            InventisBio

                            China arrow
                            EPSC
                            Not Confirmed

                            InventisBio

                            China arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : D-0120,Allopurinol

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Evaluation of PK and Safety of D-0120 and Allopurinol

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            May 04, 2022

                            Lead Product(s) : D-0120,Allopurinol

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed
                            • fda
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                            • WHO-GMP
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                            Lead Product(s) : Verinurad,Allopurinol

                            Therapeutic Area : Nephrology

                            Study Phase : Phase I

                            Sponsor : Parexel

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study in Healthy Subjects to Assess Drug Availability of 4 Different Formulations of Verinurad and Allopurin...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 16, 2020

                            Lead Product(s) : Verinurad,Allopurinol

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase I

                            Sponsor : Parexel

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Verinurad,Allopurinol

                            Therapeutic Area : Nephrology

                            Study Phase : Phase I

                            Sponsor : Parexel

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pharmacokinetics of Verinurad and Allopurinol in Combination With Cyclosporine and Rifampicin in Healthy Volun...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 31, 2020

                            Lead Product(s) : Verinurad,Allopurinol

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase I

                            Sponsor : Parexel

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Arthrosi Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Arthrosi Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : AR882,Allopurinol,Febuxostat

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The Study is Designed to Evaluate Single Ascending Doses of AR882 in Healthy Adult Males

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 15, 2020

                            Lead Product(s) : AR882,Allopurinol,Febuxostat

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Verinurad,Allopurinol

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of Verinurad in Heart Failure With Preserved Ejection Fraction

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 30, 2020

                            Lead Product(s) : Verinurad,Allopurinol

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Verinurad,Allopurinol

                            Therapeutic Area : Nephrology

                            Study Phase : Phase I

                            Sponsor : Parexel

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Assess the Effect of Verinurad on the Electric Activity of the Heart

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 05, 2020

                            Lead Product(s) : Verinurad,Allopurinol

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase I

                            Sponsor : Parexel

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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