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    CAS 119770-60-4

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    CAS 119770-60-4
    Also known as: 119770-60-4, 107256-31-5, 3-[2-(3-chlorophenyl)ethyl]-2-pyridyl 1-methyl-4-piperidyl ketone hydrochloride, (1-methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone hydrochloride, [3-[2-(3-chlorophenyl)ethyl]pyridin-2-yl]-(1-methylpiperidin-4-yl)methanone;hydrochloride, 3-[2-(3-chlorophenyl)ethyl]-2-pyridinyl-(1-methyl-4-piperidinyl)methanone hydrochloride
    Molecular Formula
    C20H24Cl2N2O
    Molecular Weight
    379.3  g/mol
    InChI Key
    YDOROGMYGIAIPT-UHFFFAOYSA-N
    1 2D Structure

    CAS 119770-60-4

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [3-[2-(3-chlorophenyl)ethyl]pyridin-2-yl]-(1-methylpiperidin-4-yl)methanone;hydrochloride
    2.1.2 InChI
    InChI=1S/C20H23ClN2O.ClH/c1-23-12-9-17(10-13-23)20(24)19-16(5-3-11-22-19)8-7-15-4-2-6-18(21)14-15;/h2-6,11,14,17H,7-10,12-13H2,1H3;1H
    2.1.3 InChI Key
    YDOROGMYGIAIPT-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN1CCC(CC1)C(=O)C2=C(C=CC=N2)CCC3=CC(=CC=C3)Cl.Cl
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. 119770-60-4

    2. 107256-31-5

    3. 3-[2-(3-chlorophenyl)ethyl]-2-pyridyl 1-methyl-4-piperidyl Ketone Hydrochloride

    4. (1-methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone Hydrochloride

    5. [3-[2-(3-chlorophenyl)ethyl]pyridin-2-yl]-(1-methylpiperidin-4-yl)methanone;hydrochloride

    6. 3-[2-(3-chlorophenyl)ethyl]-2-pyridinyl-(1-methyl-4-piperidinyl)methanone Hydrochloride

    7. 1-(methyl-4-piperidinyl)-(3-(2-(3-chlorophenyl)ethyl)-2-pyridinyl) Methanone Hydrochloride

    8. Methanone, [3-[2-(3-chlorophenyl)ethyl]-2-pyridinyl](1-methyl-4-piperidinyl)-, Hydrochloride (1:1)

    9. Loratadine Ketone

    10. Schembl7671363

    11. Akos005217016

    12. 770c604

    13. (1-methyl-4-piperidinyl)[3-[ 2-(3-chlorophenyl)ethyl]-2-pyridinyl]methanone Hydrochloride

    14. (1-methyl-4-piperidinyl)[3-[2-( 3-chlorophenyl)ethyl]-2-pyridinyl]methanone Hydrochloride

    15. [3-[2-(3-chlorophenyl) Ethyl]-2-pyridinyl]-1-methyl-4-piperidinyl Methanone Hydrochloride

    16. [3-[2-(3-chlorophenyl)ethyl]-2-pyridinyl]-1-methyl-4-piperidinyl Methanone Hydrochloride

    17. Loratadine Impurity ((1-methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone)

    2.3 Create Date
    2007-02-08
    3 Chemical and Physical Properties
    Molecular Weight 379.3 g/mol
    Molecular Formula C20H24Cl2N2O
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count5
    Exact Mass378.1265688 g/mol
    Monoisotopic Mass378.1265688 g/mol
    Topological Polar Surface Area33.2 Ų
    Heavy Atom Count25
    Formal Charge0
    Complexity408
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
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                                    Loratadine
                                    Aurore Life Sciences is a pure-play API manufacturer with a diverse portfolio of capabilities in deliveri...
                                    Aurore Life Sciences is a pure-play API manufacturer with a diverse portfolio of capabilities in delivering efficiencies to generic players globally. Founded in 2017 by a team with vast experience across the pharmaceutical value chain, the company is on a mission to become the most preferred partner for pharmaceuticals. At Aurore, we aim to push the boundaries to manufacture and deliver high quality products that can be relied upon by both customers and regulators. Our thrust on rapidly adding capabilities have led us to acquire, integrate and expand our reach across the geographies.
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                                    Chengda Pharmaceuticals

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                                    2-cyano-3-methylpyridine

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                                    20970-75-6
                                    Loratadine
                                    Chengda Pharmaceutical Co., Ltd. was founded in 1999. It is located in the Hangzhou-Jiaxing-Huzhou plain,...
                                    Chengda Pharmaceutical Co., Ltd. was founded in 1999. It is located in the Hangzhou-Jiaxing-Huzhou plain, Jiashan Economic & Technological Development Zone (national level). The company has two production plants, No. 5 Hengshan Road and No. 36 Huanghe Road. It covers an area of 123,743 square meters & a building area of 67,760 square meters. The company is a high-tech enterprise with a provincial research & development center. The company mainly produces raw materials, food additives, feed additives & antibiotics, anti-cancer, anti-virus & other series of pharmaceutical intermediates, the products are sold to more than 30 countries.
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                                    Jinan Lead Pharmaceutical Technolog...

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                                      8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-...

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                                      CAS-38092-89-6
                                      Loratadine
                                      Jinan Lead Pharmaceutical Technology Co., LTD., located in Jinan, Shandong Province, is mainly engaged in...
                                      Jinan Lead Pharmaceutical Technology Co., LTD., located in Jinan, Shandong Province, is mainly engaged in R&D, production and sales of pharmaceutical raw materials and intermediates. The research and development center is located in Jinan high-tech zone, the production base is located in Ulanqab, Inner Mongolia. The plant has 6 production workshops, covering an area of 1,000,000㎡. At present, we have passed the supplier audit from many domestic pharmaceutical enterprises and world-class pharmaceutical enterprises. Main business: pharmaceutical API and intermediate research and development, production and sales.
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                                      Morepen Laboratories

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                                      8-Chloro-10, 11-dihydro-4-aza-5H-dibenzo (a, d)cyclohep...

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                                      31251-41-9
                                      Loratadine
                                      Morepen Laboratories Ltd.’ is 31 years old company. Went to public in 1993. Manufacturer and Exporter o...
                                      Morepen Laboratories Ltd.’ is 31 years old company. Went to public in 1993. Manufacturer and Exporter of complex and high margins molecules (APIs/Intermediates) for regulated markets of USA, Europe, Russia, Canada and also for non-regulated markets. The first Morepen manufacturing plant was set up on the foothills of the Himalayas in the idyllic surroundings of Parwanoo. The large and spread-out facility is USDFA approved for manufacture of Loratadine, an anti-allergy drug- internationally known as Claritin.
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                                      Morepen Laboratories

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                                      11-(N-Methyl-4-piperidinylidene)-8-chloro-6,11-dihydro-...

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                                      38092-89-6
                                      Loratadine
                                      Morepen Laboratories Ltd.’ is 31 years old company. Went to public in 1993. Manufacturer and Exporter o...
                                      Morepen Laboratories Ltd.’ is 31 years old company. Went to public in 1993. Manufacturer and Exporter of complex and high margins molecules (APIs/Intermediates) for regulated markets of USA, Europe, Russia, Canada and also for non-regulated markets. The first Morepen manufacturing plant was set up on the foothills of the Himalayas in the idyllic surroundings of Parwanoo. The large and spread-out facility is USDFA approved for manufacture of Loratadine, an anti-allergy drug- internationally known as Claritin.
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                                      Morepen Laboratories

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                                      11-(N-Methyl-4-piperidinyl)-8-chloro-11-hydroxy- 6,11-d...

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                                      38089-93-9
                                      Loratadine
                                      Morepen Laboratories Ltd.’ is 31 years old company. Went to public in 1993. Manufacturer and Exporter o...
                                      Morepen Laboratories Ltd.’ is 31 years old company. Went to public in 1993. Manufacturer and Exporter of complex and high margins molecules (APIs/Intermediates) for regulated markets of USA, Europe, Russia, Canada and also for non-regulated markets. The first Morepen manufacturing plant was set up on the foothills of the Himalayas in the idyllic surroundings of Parwanoo. The large and spread-out facility is USDFA approved for manufacture of Loratadine, an anti-allergy drug- internationally known as Claritin.
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                                      NAM Group

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                                        N-Methyl Loratadine

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                                        38092-89-6
                                        Loratadine
                                        NAM Group of Industries is a prominent manufacturer and exporter of pharmaceutical API’s for both human...
                                        NAM Group of Industries is a prominent manufacturer and exporter of pharmaceutical API’s for both human and veterinary use, along with pharmaceutical intermediates. Our cutting-edge facility spans over 5000 square meters and is equipped with the latest technology and modern equipment. It adheres to WHO GMP & CGMP standards, ensuring compliance with global pharmaceutical regulations. Our facility includes dedicated clean rooms for each category, underscoring our commitment to maintaining high standards of hygiene and quality. It is headquartered in Mumbai, with our manufacturing plant situated in Ankleshwar, Gujarat.
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                                        Vasudha Pharma Chem Limited

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                                        N-Methyl-4-chloro piperidine

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                                        5570-77-4
                                        Desloratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        cyclohepta (1,2b) pyridine (Methyl Loratadine)

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                                        38092-89-6
                                        Loratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        3(2-(3-Chloro phenyl) ethyl) cyano pyridine

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                                        31255-55-7
                                        Desloratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        N-Methyl-4-chloro piperidine

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                                        5570-77-4
                                        Loratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        3(2-(3-Chloro phenyl) ethyl) cyano pyridine

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                                        31255-55-7
                                        Loratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem

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                                        8 chloro-11-[(N-Methyl)-4-piperidylidene]- 6, 11-dihydr...

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                                        38092-89-6
                                        Desloratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        (methanol Hcl)

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                                        119770-60-4
                                        Desloratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem

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                                        8 chloro-11-[(N-Methyl)-4-piperidylidene]- 6, 11-dihydr...

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                                        38092-89-6
                                        Loratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        (methanol Hcl)

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                                        119770-60-4
                                        Loratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        8-Chloro-5,6dihydro (1H)-benzo [5,6] cyclohepta (1,2b)...

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                                        31251-41-9
                                        Desloratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        8-Chloro-5,6dihydro (1H)-benzo [5,6] cyclohepta (1,2b)...

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                                        31251-41-9
                                        Loratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        Vasudha Pharma Chem Limited

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                                        cyclohepta (1,2b) pyridine (Methyl Loratadine)

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                                        38092-89-6
                                        Desloratadine
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 i...
                                        VASUDHA PHARMA CHEM LIMITED was incorporated, as a public limited company under the Companies Act, 1956 in 1994-95 at Hyderabad in the state of Telangana, India. The company is engaged in the manufacturing of Active Pharmaceutical Ingredients (APIs), Pharma Intermediates for catering to the Global market. Initially, the focus was on the development of cost effective processes for several intermediates related to piperidone & piperidine derivatives. By 2003-04, the company gained world class expertise and became the largest manufacturer of piperidone & piperidine derivatives in the world.
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                                        veranova-m-2024-04-22

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                                        Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

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