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Find the latest Drugs in Development and Pipeline Prospector News of Vectura Ltd.

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Skyepharma RM
Vectura Ltd
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United Kingdom
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1 Prospect West, Chippenham, Wiltshire
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+33 474952020
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Details:

Under the terms of the agreement, Vectura will undertake formulation screening studies, manufacturing process optimisation studies and stability assessments, as well as manufacturing a laboratory-scale batch of IHL-216A (Cannabidiol) to support toxicological studies.


Lead Product(s): Cannabidiol,Isoflurane

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: IHL-216A

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Incannex Healthcare

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement June 22, 2021

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Details:

IPA-001 is inhaled formulation displayed viricidal activity against SARS-CoV2 after 5 minutes contact time. It is purified extracts from a plant source. These extracts contain proteolytic enzymes that have been shown to rapidly inactivate the SARS-CoV-2 virus in vitro.


Lead Product(s): IPA-001

Therapeutic Area: Infections and Infectious Diseases Product Name: IPA-001

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Inspira

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement May 06, 2021

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Hikma will immediately resume launch activities of its generic product for Advair Diskus® (Fluticasone Propionate and Salmeterol Inhalation Powder, USP), 100mcg/50mcg and 250mcg/50mcg doses in the US.


Lead Product(s): Fluticasone Propionate,Salmeterol Xinafoate

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Fluticasone Propionate/Salmeterol-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Hikma Pharmaceuticals

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 21, 2021

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Details:

The new device is an evolution of Vectura’s lever-operated multi-dose (LOMI) device and builds on Vectura and Hikma’s shared experience with the generic Advair Diskus® programme, enabling accelerated development under this agreement.


Lead Product(s): Fluticasone Propionate,Salmeterol Xinafoate

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Fluticasone Propionate/Salmeterol-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Hikma Pharmaceuticals

Deal Size: $95.0 million Upfront Cash: $15.0 million

Deal Type: Agreement December 17, 2020

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This agreement provides an opportunity for Vectura to realise value from its historical research and investment in VR588, whilst expanding its CDMO development services portfolio by supporting the product's further development with Kinaset.


Lead Product(s): VR588

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: VR588

Highest Development Status: Phase IProduct Type: Small molecule

Recipient: Kinaset Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement November 30, 2020

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Details:

Fluticasone Propionate / Salmeterol or VR315 is a generic, inhaled combination therapy for asthma/COPD delivered using Vectura's proprietary dry powder inhaler and formulation technology.


Lead Product(s): Fluticasone Propionate,Salmeterol Xinafoate

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: VR315

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Hikma Pharmaceuticals

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 22, 2020

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Details:

Vectura will support the development of a single use device/formulation combination for evaluation in Phase I of inhaled oxytocin, and then expedite technical transfer to a commercial manufacturer to advance to Phase III and commercial launch.


Lead Product(s): Oxytocin

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Peptide

Partner/Sponsor/Collaborator: Monash University

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement September 14, 2020

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Details:

QVM149 combines the bronchodilation of indacaterol acetate (a LABA) and the antimuscarinic effects of glycopyrronium bromide (a LAMA) with mometasone furoate in a precise once-daily formulation, delivered via the dose-confirming Breezhaler® device.


Lead Product(s): Indacaterol Acetate,Glycopyrronium Bromide,Mometasone Furoate

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Enerzair Breezhaler

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Novartis Pharmaceuticals Corporation

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 07, 2020

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Details:

Aerami will be responsible for the overall development and commercialisation of inhaled imatinib, with Vectura providing development services expertise and a license to its FOX® mesh nebuliser technology.


Lead Product(s): Imatinib Mesylate

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Undisclosed

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Aerami

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement June 08, 2020

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