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ADU-1805 is a monoclonal antibody which blocks SIRPα, a significant immune-suppressive component of the tumor microenvironment which leads in improved immune system’s ability to attack tumors.


Lead Product(s): ADU-1805

Therapeutic Area: Oncology Product Name: ADU-1805

Highest Development Status: IND EnablingProduct Type: Large molecule

Partner/Sponsor/Collaborator: Exelixis

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 13, 2023

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Exelixis and Sairopa will develop ADU-1805, a potentially best-in-class monoclonal antibody that targets SIRPα. ADU-1805 is active against all human alleles of SIRPα, which may allow it to address a broader patient population than other SIRPα-directed therapies.


Lead Product(s): ADU-1805

Therapeutic Area: Oncology Product Name: ADU-1805

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Exelixis

Deal Size: $335.0 million Upfront Cash: $40.0 million

Deal Type: Collaboration November 01, 2022

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