Company profile for Apogee Therapeutics

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About

Apogee Therapeutics is a biotechnology company seeking to develop differentiated biologics for the treatment of atopic dermatitis (AD), chronic obstructive pulmonary disease (COPD), and other inflammatory and immune (I&I) diseases with high unmet needs. Its pipeline of differentiated antibody therapeutics targets well-established biological drivers and development pathways, with an initial focus on making impactful advancement...
Apogee Therapeutics is a biotechnology company seeking to develop differentiated biologics for the treatment of atopic dermatitis (AD), chronic obstructive pulmonary disease (COPD), and other inflammatory and immune (I&I) diseases with high unmet needs. Its pipeline of differentiated antibody therapeutics targets well-established biological drivers and development pathways, with an initial focus on making impactful advancements in the treatment of atopic dermatitis and chronic obstructive pulmonary disease.

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U.S.A
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Address
221 Crescent St Waltham, MA 02453
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NEWS #PharmaBuzz

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https://www.globenewswire.com/news-release/2026/01/05/3213173/0/en/Apogee-Therapeutics-to-Host-Conference-Call-to-Report-Interim-Results-from-the-Phase-1b-Trial-of-APG777-in-Patients-with-Mild-to-Moderate-Asthma-and-2026-Anticipated-Milestones-on-.html

GLOBENEWSWIRE
05 Jan 2026

https://www.globenewswire.com/news-release/2025/11/10/3184408/0/en/Apogee-Therapeutics-Provides-Pipeline-Progress-and-Reports-Third-Quarter-2025-Financial-Results.html

GLOBENEWSWIRE
10 Nov 2025

https://www.globenewswire.com/news-release/2025/11/10/3184340/0/en/Apogee-Therapeutics-Announces-Positive-Interim-Phase-1-Results-from-Healthy-Volunteer-Trial-of-APG333-its-Novel-Half-Life-Extended-TSLP-Antibody.html

GLOBENEWSWIRE
10 Nov 2025

https://www.globenewswire.com/news-release/2025/10/10/3165093/0/en/Apogee-Therapeutics-Inc-Announces-Closing-of-Public-Offering-and-Full-Exercise-of-the-Underwriters-Option-to-Purchase-Additional-Shares-for-Gross-Proceeds-of-345-Million.html

GLOBENEWSWIRE
10 Oct 2025

https://www.globenewswire.com/news-release/2025/10/09/3163822/0/en/Apogee-Therapeutics-Inc-Announces-Pricing-of-300-Million-Underwritten-Public-Offering.html

GLOBENEWSWIRE
08 Oct 2025

https://www.globenewswire.com/news-release/2025/10/08/3163716/0/en/Apogee-Therapeutics-Inc-Announces-Proposed-Underwritten-Public-Offering.html

GLOBENEWSWIRE
08 Oct 2025

Drugs in Development

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Details:

The proceeds from the offering will be used to fund the clinical development of APG777, an antibody targeting IL-13 receptor for inflammatory and immunology markets.


Lead Product(s): APG777

Therapeutic Area: Dermatology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Antibody, Unconjugated

Sponsor: Jefferies | BofA Securities | Guggenheim Securities | TD Cowen

Deal Size: $345.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering October 10, 2025

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Biotech Showcase
Not Confirmed
Biotech Showcase
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Lead Product(s) : APG777

Therapeutic Area : Dermatology

Highest Development Status : Phase II

Partner/Sponsor/Collaborator : Jefferies | BofA Securities | Guggenheim Securities | TD Cowen

Deal Size : $345.0 million

Deal Type : Public Offering

Details : The proceeds from the offering will be used to fund the clinical development of APG777, an antibody targeting IL-13 receptor for inflammatory and immunology markets.

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Undisclosed

October 10, 2025

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Details:

In the public offering, APG777, an unconjugated antibody targeting IL-13 receptor, aims to advance in the inflammatory and immunology (I&I) space.


Lead Product(s): APG777

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: APG777

Study Phase: PreclinicalProduct Type: Antibody, Unconjugated

Sponsor: Jefferies

Deal Size: $300.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering October 08, 2025

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02

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Details : In the public offering, APG777, an unconjugated antibody targeting IL-13 receptor, aims to advance in the inflammatory and immunology (I&I) space.

Product Name : APG777

Product Type : Antibody, Unconjugated

Upfront Cash : Undisclosed

October 08, 2025

blank

Details:

In the public offering, APG777, an unconjugated antibody targeting IL-13 receptor, aims to advance in the inflammatory and immunology (I&I) markets.


Lead Product(s): APG777

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: APG777

Study Phase: PreclinicalProduct Type: Antibody, Unconjugated

Sponsor: Jefferies

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Public Offering October 08, 2025

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03

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Details : In the public offering, APG777, an unconjugated antibody targeting IL-13 receptor, aims to advance in the inflammatory and immunology (I&I) markets.

Product Name : APG777

Product Type : Antibody, Unconjugated

Upfront Cash : Undisclosed

October 08, 2025

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Details:

APG777 is a Antibody drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Dermatitis, Atopic.


Lead Product(s): APG777,APG990

Therapeutic Area: Dermatology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Antibody, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable June 18, 2025

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04

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Lead Product(s) : APG777,APG990

Therapeutic Area : Dermatology

Highest Development Status : Phase I

Partner/Sponsor/Collaborator : Undisclosed

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : APG777 is a Antibody drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Dermatitis, Atopic.

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Inapplicable

June 18, 2025

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Details:

APG777 is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Dermatitis, Atopic.


Lead Product(s): APG777

Therapeutic Area: Dermatology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Antibody, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable June 04, 2025

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05

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Details : APG777 is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Dermatitis, Atopic.

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Inapplicable

June 04, 2025

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Details:

APG808 is a novel half-life extended IL-4Rα antibody, which is currently being evaluated for the treatment of mild-to-moderate asthma.


Lead Product(s): APG808

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable May 12, 2025

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06

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Details : APG808 is a novel half-life extended IL-4Rα antibody, which is currently being evaluated for the treatment of mild-to-moderate asthma.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

May 12, 2025

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Details:

APG777 is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Asthma.


Lead Product(s): APG777

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Antibody, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable April 10, 2025

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07

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Details : APG777 is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Asthma.

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Inapplicable

April 10, 2025

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Details:

APG990 is a novel, SQ, half-life extended mAb targeting OX40L


Lead Product(s): APG990

Therapeutic Area: Dermatology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Antibody, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable March 03, 2025

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08

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Details : APG990 is a novel, SQ, half-life extended mAb targeting OX40L

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Inapplicable

March 03, 2025

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Details:

APG777 is a IL-13 inhibitor antibody candidate, which is being evaluated in clinical trial studies for the treatment of patients with atopic dermatitis.


Lead Product(s): APG777

Therapeutic Area: Dermatology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Antibody, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 03, 2025

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09

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Details : APG777 is a IL-13 inhibitor antibody candidate, which is being evaluated in clinical trial studies for the treatment of patients with atopic dermatitis.

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Inapplicable

February 03, 2025

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Details:

APG333 is a novel, SQ extended half-life mAb targeting TSLP, a key driver of Type 2 and Type 3 inflammation in eosinophilic and non-eosinophilic conditions, like asthma, COPD.


Lead Product(s): APG333

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 10, 2024

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10

Biotech Showcase
Not Confirmed
Biotech Showcase
Not Confirmed

Details : APG333 is a novel, SQ extended half-life mAb targeting TSLP, a key driver of Type 2 and Type 3 inflammation in eosinophilic and non-eosinophilic conditions, like asthma, COPD.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

December 10, 2024

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