Looking for Solubilizers? Find Solubilizers Agents used in Chloroxylenol to address drug delivery challenges on PharmaCompass.

China

Benzyl alcohol is used as a bacteriostatic and preservative agent in parenteral dosage forms including biologics & vaccines. It is widely used in oral formulations such as tablets and liquids and topical preparations such as ointments, and gels.

BENZYL ALCOHOL

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Ingredient(s): Benzyl Alcohol

Dosage Form: Cream / Lotion / Ointment, Gel, Injectable / Parenteral, Tablet

Category: Parenteral, Solubilizers, Topical

Route of Administration (Grade): Parenteral, Oral, Topical

Pharmacopoeia Reference: ChP/USP/EP/JP

Technical Specifications: NA

CPhI China

Booth# E3D78a

DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

DKSH

Switzerland

Urea's applications include solubilizing proteins from inclusion bodies, increasing solubility of hydrophobic peptides, proteins & denaturing proteins

UREA

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Ingredient(s): Urea

Dosage Form: Cream / Lotion / Ointment

Category: Solubilizers, Topical

Route of Administration (Grade): Topical

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

CPhI China

Booth #W5P10

Evonik's CDMO solutions for APIs and HPAPIs: It specializes where the client needs it most!

Evonik

Germany

EUDRAGIT® L 100-55 polymer is used in delayed, sustained-release coatings to enhance solubility of poorly soluble drugs such as tablets, capsules, etc.

EUDRAGIT® L 100-55

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Ingredient(s): Methacrylic Acid - Ethyl Acrylate Copolymer

Dosage Form: Capsule, Granule / Pellet, Tablet

Category: Controlled & Modified Release, Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: NA

Technical Specifications: Available as powder; Other grades- EUDRAGIT® L 30 D-55

Formulation & Delivery

Attending

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Nanjing Well Pharmaceutical

China

Polysorbate 20 is used as a solubilizer (wetting agent) in oral dosage forms such as tablets and topical dosage forms such as creams, ointments, lotions, and gels. It is also used in parenteral dosage forms including biologics and vaccines.

POLYSORBATE 20 NF

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Ingredient(s): Polysorbate 20

Dosage Form: Cream / Lotion / Ointment, Gel, Injectable / Parenteral, Tablet

Category: Parenteral, Solubilizers, Topical

Route of Administration (Grade): Parenteral, Oral, Topical

Pharmacopoeia Reference: ChP/USP/EP

Technical Specifications: NA

CPhI China

Booth# E3D78a

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Nanjing Well Pharmaceutical

China

Polyoxyl (40) hydrogenated castor oil is used as a wetting agent in oral dosage forms such as tablets. It is also used in SEDDS and as a solubilizer in topical dosage forms such as creams, lotions, ointments, and gels.

POLYOXYL 40 HYDROGENATED CASTOR OIL

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Ingredient(s): Polyoxyl 40 Hydrogenated Castor Oil

Dosage Form: Cream / Lotion / Ointment, Tablet

Category: Solubilizers, Topical

Route of Administration (Grade): Oral, Topical

Pharmacopoeia Reference: ChP/USP/EP

Technical Specifications: NA

Nanjing Well Polyoxyl 40 Hydrogenated Castor Oil

CPhI China

Booth# E3D78a

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Nanjing Well Pharmaceutical

China

Polyoxyl 20 cetostearyl ether is used as a wetting agent in oral dosage forms such as tablets. It is also used as a solubilizer in topical formulations such as lotions, ointments, and gels.

POLYOXYL 20 CETOSTEARYL ETHER

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Ingredient(s): Polyoxyl 20 Cetostearyl Ether

Dosage Form: Cream / Lotion / Ointment, Gel, Tablet

Category: Solubilizers, Topical

Route of Administration (Grade): Oral, Topical

Pharmacopoeia Reference: USP/EP

Technical Specifications: NA

Nanjing Well Polyoxyl 20 Cetostearyl Ether

CPhI China

Booth# E3D78a

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Nanjing Well Pharmaceutical

China

Butylene glycol has a good antibacterial effect and is used in topical dosage forms such as creams, lotions, ointments, and gels.

BUTYLENE GLYCOL

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Ingredient(s): Butylene glycol

Dosage Form: Cream / Lotion / Ointment, Gel, Injectable / Parenteral, Tablet

Category: Parenteral, Solubilizers, Topical

Route of Administration (Grade): Topical

Pharmacopoeia Reference: USP

Technical Specifications: NA

CPhI China

Booth# E3D78a

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Nanjing Well Pharmaceutical

China

Oleic acid is used as a solubilizer (wetting agent) in parenteral dosage forms. It is also used as a co-emulsifier, plasticizer, and film agent in softgel capsules, and emulsions and as a transdermal penetration enhancer in topical formulations.

OLEIC ACID

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Ingredient(s): Oleic Acid Excipient

Dosage Form: Capsule, Emulsion, Injectable / Parenteral, Softgels

Category: Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers

Route of Administration (Grade): Parenteral, Oral

Pharmacopoeia Reference: USP/EP/ChP

Technical Specifications: NA

CPhI China

Booth# E3D78a

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BioSpectra

U.S.A

Its applications include solubilizing proteins from inclusion bodies, increasing solubility of hydrophobic peptides and proteins and denaturing proteins. Urea may be used with guanidine hydrochloride in the refolding of denatured proteins.

UREA

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Ingredient(s): Urea

Dosage Form: Cream / Lotion / Ointment

Category: Solubilizers, Topical

Route of Administration (Grade): Topical

Pharmacopoeia Reference: Not Available

Technical Specifications: Bio Excipient Grade

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Actylis

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U.S.A

A&C’s Benzalkonium Chloride 17% is a preservative which meets the NF monograph.

BENZALKONIUM CHLORIDE 17% USP NF

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Ingredient(s): Benzalkonium chloride excipient

Dosage Form: Injectable / Parenteral, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral, Parenteral

Pharmacopoeia Reference: USP NF

Technical Specifications: 17% USP NF

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BASF

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Germany

Nonionic solubilizer, emulsifier and co-emulsifier

KOLLIPHOR PS 20

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Ingredient(s): Polysorbate 20

Dosage Form: Gel, Softgel Capsule, Solution, Suppository

Category: Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur., USP-NF

Technical Specifications: Not Available

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Actylis

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U.S.A

A&C’s Benzalkonium Chloride 50% is a preservative which meets the NF monograph. It acts as a quarternary ammonium salt.

BENZALKONIUM CHLORIDE 50% NF

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Ingredient(s): Benzalkonium chloride excipient

Dosage Form: Injectable / Parenteral, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral, Parenteral

Pharmacopoeia Reference: NF

Technical Specifications: 50% NF

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Seppic

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France

Non-Ionic Hydrophilic Surfactant, Emulsifier, Solubilizer

MONTANOX 20 PHA PREMIUM

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Ingredient(s): Polysorbate 20

Dosage Form: Capsule, Cream / Lotion / Ointment, Gel, Shampoo, Solution, Syrup, Tablet

Category: Solubilizers, Surfactant & Foaming Agents, Topical

Route of Administration (Grade): Topical, Oral

Pharmacopoeia Reference: Ph.Eur, USP-NF

Technical Specifications: HLB: 17, EO: 20; EXCiPACT

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Huzhou Sunflower Pharmaceutical

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China

Copovidone is used as a tablet binder, a film-former, & as part of the matrix material used in controlled-release formulations. It can be used as a binder for direct compression & wet granulation.

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COPOVIDONE

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Ingredient(s): Copovidone K25-31

Dosage Form: Tablet

Category: Controlled & Modified Release, Fillers, Diluents & Binders, Film Formers & Plasticizers, Solubilizers, Taste Masking

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Finar

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India

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UREA

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Ingredient(s): Urea

Dosage Form: Cream / Lotion / Ointment

Category: Topical

Route of Administration (Grade): Topical

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Ulanqab Kema New Material

China

Povidone excipient is used as a binder in oral solid dosage forms such as effervescent tablets and sustained-release capsules. It is also used in the formation of direct compression granules and tablets.

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POVIDONE

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Ingredient(s): Povidone

Dosage Form: Capsule, Granule / Pellet, Tablet

Category: Direct Compression, Fillers, Diluents & Binders

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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The Dow Chemical Company

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U.S.A

Solubility enhancement, Spray-Dried Dispersion (SDD), Hot Melt Extrusion (HME)

AFFINISOL HPMC HME

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Ingredient(s): Hydroxypropyl Methylcellulose

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Actylis

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U.S.A

A & C's Benzethonium Chloride USP is a hygroscopic excipient, which meets USP requirements.

BENZETHONIUM CHLORIDE USP

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Ingredient(s): Benzethonium Chloride Exc

Dosage Form: Injectable / Parenteral, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral, Parenteral

Pharmacopoeia Reference: USP

Technical Specifications: 17% USP NF; 50% NF; USP

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Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

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China

Disintegrant; Dissolution enhancer; Suspending Agent, Tablet Binder.

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POVIDONE

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Ingredient(s): Povidone

Dosage Form: Tablet

Category: Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: USP/BP/EP/CP

Technical Specifications: Not Available

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Finar

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India

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BENZYL ALCOHOL

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Ingredient(s): Benzyl Alcohol

Dosage Form: Cream / Lotion / Ointment, Injectable / Parenteral

Category: Parenteral, Topical

Route of Administration (Grade): Parenteral and Topical

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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BASF

Germany

Solubiliser, Plasticizer for coating & polymeric matrices, Nonionic emulsifier for O-W emulsions.

KOLLIPHOR RH40

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Ingredient(s): Polyoxyl Hydogenated Castor Oil

Dosage Form: Capsule, Emulsion, Softgel Capsule, Tablet

Category: Film Formers & Plasticizers, Granulation, Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur: Macrogolglycerol Hydroxystearate, USP-NF: Polyoxyl 40 hydrogenated castor oil

Technical Specifications: Not Available

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Alcedo Pharmachem

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India

It is an anionic copolymer used in delayed and sustained release coatings to enhance solubility for poorly soluble drugs in solid oral dosage forms such as tablets, capsules, etc.

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LUMACRI

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Ingredient(s): Methacrylic Acid - Ethyl Acrylate Copolymer

Dosage Form: Capsule, Granule / Pellet, Tablet

Category: Coating Systems & Additives, Controlled & Modified Release, Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: NA

Technical Specifications: NA

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Gangwal Chemicals

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India

Polysorbates, TWEENs, an excipient that is used to stabilize aqueous formulations of medications and a solubilizing agent acts as a surfactant to increase the solubility in various dosge forms.

MONTANOX 20 PHA PREMIUM

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Ingredient(s): Polysorbate 20

Dosage Form: Capsule, Cream / Lotion / Ointment, Tablet, Topical Film

Category: Emulsifying Agents, Solubilizers, Surfactant & Foaming Agents, Topical

Route of Administration (Grade): Oral, Topical

Pharmacopoeia Reference: USP-NF, EP, JP

Technical Specifications: Non-Ionic Hydrophilic surfactant, Emulsifier (o/w emulsion), Solubilizer

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Actylis

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U.S.A

A & C's Polysorbate 20 is an excipient which meets the NF monograph.

POLYSORBATE 20 NF

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Ingredient(s): Polysorbate 20

Dosage Form: Capsule, Cream / Lotion / Ointment, Tablet, Topical Film

Category: Solubilizers

Route of Administration (Grade): Oral, Topical

Pharmacopoeia Reference: NF

Technical Specifications: Not Available

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Microlex e.U

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Austria

It is among the most commonly used solid dispersion carrires to solubilize poorly soluble drugs, It can stabilize amorphous drugs in polymer dispersions and maintain supersaturation of API, aqueous solutions by preventing precipitation/crystallization

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MICROLEX® PVD K30

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Ingredient(s): Povidone

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

Technical Specifications: Also Available as Microlex® PVD K90.

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BASF

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Germany

Liquid plasticizer with high ADI, hydrophilic solvent & humectant in emulsions, skin penetration enhancer in topical formulaitons.

KOLLISOLV PG

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Ingredient(s): Propylene Glycol

Dosage Form: Capsule, Emulsion, Softgel Capsule, Solution, Tablet, Topical Film

Category: Film Formers & Plasticizers, Solubilizers, Topical

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur., JP, FCC, USP

Technical Specifications: Not Available

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Microlex e.U

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Austria

Provides a matrix to solubilize poorly soluble drugs in melt-extruded or spray-dried solid dispersions.

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MICROLEX® C.PVD S600

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Ingredient(s): Copovidone K25-31

Dosage Form: Tablet

Category: Coating Systems & Additives, Fillers, Diluents & Binders, Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

Technical Specifications: Not Available

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Gangwal Chemicals

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India

Enteric, Delayed Release Matrix and Solubility Enhancement

POLYQUID PA-100

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Ingredient(s): Methacrylic Acid - Ethyl Acrylate Copolymer

Dosage Form: Capsule, Tablet

Category: Coating Systems & Additives, Controlled & Modified Release, Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Multicompendial

Technical Specifications: Methylacryli acid and Ethyl Acrylate copolymer (1:1) Type A

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Seppic

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France

Non-Ionic Hydrophilic Surfactant, Emulsifier, Solubilizer

MONTANOX 20 PPI

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Ingredient(s): Polysorbate 20

Dosage Form: Injectable / Parenteral, Nasal Solution, Ophthalmic Solution

Category: Parenteral, Solubilizers

Route of Administration (Grade): Injectable

Pharmacopoeia Reference: Ph.Eur, USP-NF, JPE

Technical Specifications: EXCiPACT

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BASF

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Germany

Co-emulsifier, viscosity enhancer & anti-tacking agent

KOLLIWAX GMS II

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Ingredient(s): Glyceryl Monostearate With Mono & Di Glycerides

Dosage Form: Cream / Lotion / Ointment, Emulsion, Gel, Softgel Capsule, Tablet

Category: Coating Systems & Additives, Solubilizers, Topical

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur.: Glyceryl monostearate 40-55 (type II), USP-NF: Mono- and di-glycerides

Technical Specifications: Not Available

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Corel Pharma Chem

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India

Solubilizer, dissolution improver, emulsifier, masking agent, moisturizer, aerosol formulations.

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ACRYSOL K-140

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Ingredient(s): Polyoxyl 40 Hydrogenated Castor Oil

Dosage Form: Emulsion, Injectable / Parenteral, Solution, Suspension

Category: Emulsifying Agents, Parenteral, Solubilizers

Route of Administration (Grade): Oral and Parenteral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Seppic

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France

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SEPITRAP 4000

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Solubilizer

Ingredient(s): Polyoxyl 40 hydrogenated castor oil

Dosage Form: Capsule, Tablet, Dry Syrup

Category: Co-Processed Excipients, Direct Compression, Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Solubilizer in powder form; EXCiPACT

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Gangwal Chemicals

India

Polyoxyl 40 hydrogenated castor oil is used as solubilizer and emulsifying agent.

SEPITRAP 4000

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Ingredient(s): Magnesium Aluminometasilicate, Polyoxyl 40 Hydrogenated Castor Oil

Dosage Form: Tablet, Capsule

Category: API Stability Enhancers, Direct Compression, Solubilizers, Thickeners and Stabilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: USP-NF, EP, JP

Technical Specifications: Solubilizer in powder form, used in Directly compressible dosage forms, Wet granulation, added during lubrication stage

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Gangwal Chemicals

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India

Kovidone- K series products posses excellent binding, film-forming, dispersing, and thickning properties and are widely used in the following dosage forms. Binder, Solubilizer, Coating agent, Suspending, Stabilizing or viscocity modifying agent

KOVIDONE-K

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Ingredient(s): Crospovidone, Povidone

Dosage Form: Capsule, Tablet

Category: Coating Systems & Additives, Fillers, Diluents & Binders, Film Formers & Plasticizers, Solubilizers, Thickeners and Stabilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: USP-NF, EP, BP, IP, JP, FCC

Technical Specifications: PVP K-K-30/ K-17/ K19/ K25/ K90

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BASF

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Germany

Nonionic emulsifier for O-W emulsions

KOLLIPHOR CS 20

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Ingredient(s): CETEARETH-12, Polyoxyl 20 Cetostearyl Ether

Dosage Form: Cream / Lotion / Ointment, Emulsion, Gel

Category: Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur.: Macrogol cetostearyl ether 20, USP-NF: Polyoxyl 20 cetostearyl ether

Technical Specifications: Not Available

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BASF

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Germany

Solubilization, dispersion, crystallization inhibition, instant release matrices & spray drying

KOLLIDON 30

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Ingredient(s): Povidone

Dosage Form: Capsule, Tablet, Transdermal Patch, Transdermal patches

Category: Controlled & Modified Release, Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur., USP, JP: Povidone

Technical Specifications: Not Available

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BASF

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Germany

Tablet binding, thickener, stabilizers of suspensions, reduces sedimentation, crystallization inhibition.

KOLLIDON 90 F

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Ingredient(s): Povidone

Dosage Form: Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

Category: Fillers, Diluents & Binders, Granulation, Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur., USP, JP: Povidone

Technical Specifications: Not Available

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BASF

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Germany

Liquid plasticizer for tablet coatings, solvent for APIs, dispersing agent, stabilizer and co-emulsifier in semi-solid formulations.

KOLLISOLV P124

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Ingredient(s): Poloxamer 124

Dosage Form: Emulsion

Category: Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur., USP-NF: Poloxamer 124; JPE: Polyoxyethylene (20) Polyoxypropylene (20) Glycol

Technical Specifications: Not Available

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BASF

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Germany

Solubilizing matrix, crystallization inhibitor & stabilizer in injectables and ophthalmic products

KOLLIDON 17 PF

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Ingredient(s): Povidone

Dosage Form: Capsule, Emulsion, Softgel Capsule, Solution, Tablet, Transdermal patches

Category: Parenteral, Solubilizers

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: Ph. Eur., USP: Povidone; JPE: Povidone K 17

Technical Specifications: Not Available

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BASF

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Germany