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    Vadadustat

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    01 1Metrochem API Private Limited

    02 1Ami Lifesciences Private Limited

    03 1HRV Pharma

    04 1Shanvr Life Sciences

    05 1Viatris

    06 1Zydus Lifesciences

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    Metrochem API Private Limited

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    Ami Lifesciences Private Limited

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    GDUFA

    DMF Review : N/A

    Rev. Date :

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    DMF Number : 41915

    Submission : 2025-09-25

    Status : Active

    Type : II

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    HRV Pharma

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    Virtual BoothHRV Pharma - Market Expansion Leader in Pharmaceuticals.

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    Shanvr Life Sciences

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    Viatris

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    Zydus Lifesciences

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    Looking for 1000025-07-9 / Vadadustat API manufacturers, exporters & distributors?

    Vadadustat manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Vadadustat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Vadadustat manufacturer or Vadadustat supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Vadadustat manufacturer or Vadadustat supplier.

    API | Excipient name

    Vadadustat

    Synonyms

    1000025-07-9, Akb-6548, Pg-1016548, Vadadustat [usan], N-(5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine, B506

    Cas Number

    1000025-07-9

    Unique Ingredient Identifier (UNII)

    I60W9520VV

    About Vadadustat

    Vadadustat is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor (HIF-PHI), with potential anti-anemic and anti-inflammatory activities. Upon administration, vadadustat binds to and inhibits HIF-PH, an enzyme responsible for the degradation of transcription factors in the HIF family under normal oxygen conditions. This prevents HIF breakdown and promotes HIF activity. Increased HIF activity leads to an increase in endogenous erythropoietin production, thereby enhancing erythropoiesis. It also reduces the expression of the peptide hormone hepcidin, improves iron availability, and boosts hemoglobin (Hb) levels. HIF regulates the expression of genes in response to reduced oxygen levels, including genes required for erythropoiesis and iron metabolism. In addition, HIF 1-alpha (HIF1A) may play a role in reducing inflammation during acute lung injury (ALI) through HIF-dependent control of glucose metabolism in the alveolar epithelium.

    Vadadustat Manufacturers

    A Vadadustat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vadadustat, including repackagers and relabelers. The FDA regulates Vadadustat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vadadustat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Vadadustat manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

    Vadadustat Suppliers

    A Vadadustat supplier is an individual or a company that provides Vadadustat active pharmaceutical ingredient (API) or Vadadustat finished formulations upon request. The Vadadustat suppliers may include Vadadustat API manufacturers, exporters, distributors and traders.

    click here to find a list of Vadadustat suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

    Vadadustat Manufacturers | Traders | Suppliers

    Vadadustat Manufacturers, Traders, Suppliers 1
    34

    We have 6 companies offering Vadadustat

    Get in contact with the supplier of your choice:

    1. Metrochem API Private Limited
    2. Ami Lifesciences Private Limited
    3. HRV Pharma
    4. Shanvr Life Sciences
    5. Viatris
    6. Zydus Lifesciences
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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    • Product listings are provided for informational purposes only. We do not supply or sell any products. Any products that may be covered by patent(s) are supplied solely for uses permitted under Section 107A of the Indian Patents Act and not for commercial sale.