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    Technical details about Indoramina, learn more about the structure, uses, toxicity, action, side effects and more

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    Indoramina

    PharmaCompass

    Boai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.

    Renejix: CDMO with expertise in small molecule oral dosage, delivery tech, and multi-modality manufacturing.

    2D Structure
    1. Also known as: Indoramine, 26844-12-2, Indoramina, Wy-21901, Wy 21901, N-[1-[2-(1h-indol-3-yl)ethyl]piperidin-4-yl]benzamide
    Molecular Formula
    C22H25N3O
    Molecular Weight
    347.5  g/mol
    InChI Key
    JXZZEXZZKAWDSP-UHFFFAOYSA-N
    FDA UNII
    0Z802HMY7H
    An alpha-1 adrenergic antagonist that is commonly used as an antihypertensive agent.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-[1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl]benzamide
    2.1.2 InChI
    InChI=1S/C22H25N3O/c26-22(17-6-2-1-3-7-17)24-19-11-14-25(15-12-19)13-10-18-16-23-21-9-5-4-8-20(18)21/h1-9,16,19,23H,10-15H2,(H,24,26)
    2.1.3 InChI Key
    JXZZEXZZKAWDSP-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CN(CCC1NC(=O)C2=CC=CC=C2)CCC3=CNC4=CC=CC=C43
    2.2 Other Identifiers
    2.2.1 UNII
    0Z802HMY7H
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Wy 21901

    2. Wy-21901

    3. Wy21901

    2.3.2 Depositor-Supplied Synonyms

    1. Indoramine

    2. 26844-12-2

    3. Indoramina

    4. Wy-21901

    5. Wy 21901

    6. N-[1-[2-(1h-indol-3-yl)ethyl]piperidin-4-yl]benzamide

    7. Baratol

    8. Indoramine;wy 21901

    9. Benzamide, N-(1-(2-(1h-indol-3-yl)ethyl)-4-piperidinyl)-

    10. N-(1-(2-indol-3-ylethyl)-4-piperidyl)benzamide

    11. 0z802hmy7h

    12. Chembl279516

    13. Doralese

    14. Benzamide, N-(1-(2-indol-3-ylethyl)-4-piperidyl)-

    15. Benzamide, N-[1-(2-indol-3-ylethyl)-4-piperidyl]-

    16. Indoraminum

    17. Benzamide, N-[1-[2-(1h-indol-3-yl)ethyl]-4-piperidinyl]-

    18. Indoramine [inn-french]

    19. Indoraminum [inn-latin]

    20. Indoramina [inn-spanish]

    21. N-[1-(2-indol-3-ylethyl)-4-piperidyl]benzamide

    22. Ncgc00165810-01

    23. Einecs 248-041-5

    24. Brn 0494035

    25. Unii-0z802hmy7h

    26. Indoramin [usan:inn:ban]

    27. 3-(2-(4-benzamidopiperid-1-yl)ethyl)indole

    28. N-(1-(2-(1h-indol-3-yl)ethyl)-4-piperidinyl)benzamide

    29. 3-[2-(4-benzamidopiperidino)ethyl]indole

    30. Indoramin [inn]

    31. Indoramin [mi]

    32. Indoramin (usan/inn)

    33. Indoramin [usan]

    34. Maybridge3_004972

    35. 3-[2-(4-benzamido-1-piperidyl)ethyl]indole

    36. Indoramin [who-dd]

    37. Oprea1_130443

    38. Schembl49517

    39. Schembl49518

    40. Gtpl501

    41. Mls001182179

    42. Zinc1567

    43. Dtxsid7048370

    44. Chebi:135470

    45. Hms1445b22

    46. Hms2851p23

    47. Bdbm50033113

    48. Ccg-41146

    49. Nsc771684

    50. Pdsp1_001099

    51. Pdsp1_001423

    52. Pdsp2_001083

    53. Pdsp2_001407

    54. Akos015994528

    55. Af-0013

    56. Db08950

    57. Nsc-771684

    58. Idi1_016359

    59. Hy-12760

    60. Smr000567879

    61. Cs-0012358

    62. D04531

    63. L001292

    64. Q408963

    65. Sr-01000631243-1

    66. N-(1-[2-(1h-indol-3-yl)ethyl]-4-piperidinyl)benzamide #

    67. N-{1-[2-(1h-indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide

    68. Indoraminn-{1-[2-(1h-indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide

    69. N-{1-[2-(1h-indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide (indoramin)

    70. N-{1-[2-(1h-indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide(indoramin)

    2.4 Create Date
    2005-03-27
    3 Chemical and Physical Properties
    Molecular Weight 347.5 g/mol
    Molecular Formula C22H25N3O
    XLogP34.1
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count5
    Exact Mass347.199762429 g/mol
    Monoisotopic Mass347.199762429 g/mol
    Topological Polar Surface Area48.1 Ų
    Heavy Atom Count26
    Formal Charge0
    Complexity454
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Adrenergic alpha-1 Receptor Antagonists

    Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS. (See all compounds classified as Adrenergic alpha-1 Receptor Antagonists.)

    Antihypertensive Agents

    Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)

    4.2 ATC Code

    C - Cardiovascular system

    C02 - Antihypertensives

    C02C - Antiadrenergic agents, peripherally acting

    C02CA - Alpha-adrenoreceptor antagonists

    C02CA02 - Indoramin

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