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Technical details about Altana Pharma Oranienburg Brand of Dihydralazine Sulfate, learn more about the structure, uses, toxicity, action, side effects and more

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2D Structure
Also known as: 7327-87-9, Dihydralazine sulphate, Depressan, 1,4-dihydrazinophthalazine sulfate, Hydralazine sulfate, 1,4-dihydrazinylphthalazine sulfate
Molecular Formula
C8H12N6O4S
Molecular Weight
288.29  g/mol
InChI Key
BWHAMWGGORIDBK-UHFFFAOYSA-N
FDA UNII
1C2B1W91NK

1,4-Dihydrazinophthalazine. An antihypertensive agent with actions and uses similar to those of HYDRALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p354)
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4-hydrazinylphthalazin-1-yl)hydrazine;sulfuric acid
2.1.2 InChI
InChI=1S/C8H10N6.H2O4S/c9-11-7-5-3-1-2-4-6(5)8(12-10)14-13-7;1-5(2,3)4/h1-4H,9-10H2,(H,11,13)(H,12,14);(H2,1,2,3,4)
2.1.3 InChI Key
BWHAMWGGORIDBK-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC=C2C(=C1)C(=NN=C2NN)NN.OS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
1C2B1W91NK
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Depressan

2. Dihydralazine

3. Dihydrallazine

4. Dihydrazinophthalazin

5. Sulfate, Dihydralazine

2.3.2 Depositor-Supplied Synonyms

1. 7327-87-9

2. Dihydralazine Sulphate

3. Depressan

4. 1,4-dihydrazinophthalazine Sulfate

5. Hydralazine Sulfate

6. 1,4-dihydrazinylphthalazine Sulfate

7. Nepresol

8. Ophthazin

9. 1,4-dihydrazinophthalazine Hydrogen Sulfate

10. (4-hydrazinylphthalazin-1-yl)hydrazine;sulfuric Acid

11. 1c2b1w91nk

12. Ophthazin Sulfate

13. Ccris 5386

14. Sulfate De Dihydralazine [french]

15. Sulfate De Dihydralazine

16. Einecs 230-808-0

17. Unii-1c2b1w91nk

18. Dihydralazinsulfat

19. Phthalazine, 1,4-dihydrazino-, Sulfate (1:1)

20. Nepresol (tn)

21. Dihydralazine Sulfate,(s)

22. Dihydralazine Hydrogen Sulfate

23. Schembl1374523

24. Chembl2106266

25. Dtxsid10223501

26. Dihydralazine Sulfate [mi]

27. Bcp11859

28. Dihydralazine For System Suitability

29. Hy-n7065

30. Mfcd00035271

31. S5030

32. Dihydralazine Sulfate [mart.]

33. Akos015960760

34. Akos037643215

35. Dihydralazine Sulfate [who-dd]

36. Ccg-267357

37. Cs-w012211

38. Sb67406

39. Ac-12152

40. As-10957

41. Ft-0731572

42. (4-hydrazinylphthalazin-1-yl)hydrazine Sulfate

43. C76337

44. D07830

45. 327d879

46. A920291

47. 1,4-dihydrazinophthalazine Hydrogen Sulphate

48. W-104459

49. Q27252218

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 288.29 g/mol
Molecular Formula C8H12N6O4S
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count10
Rotatable Bond Count2
Exact Mass288.06407406 g/mol
Monoisotopic Mass288.06407406 g/mol
Topological Polar Surface Area185 Ų
Heavy Atom Count19
Formal Charge0
Complexity248
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antihypertensive Agents

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)


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