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    Also known as: 1092939-17-7, Jakafi, (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate, Jakavi, Ruxolitinib (phosphate), Ruxolitinib monophosphate
    Molecular Formula
    C17H21N6O4P
    Molecular Weight
    404.4  g/mol
    InChI Key
    JFMWPOCYMYGEDM-XFULWGLBSA-N
    FDA UNII
    436LRU32H5
    Ruxolitinib Phosphate
    Ruxolitinib Phosphate is the phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.
    1 2D Structure

    Ruxolitinib Phosphate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
    2.1.2 InChI
    InChI=1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/m1./s1
    2.1.3 InChI Key
    JFMWPOCYMYGEDM-XFULWGLBSA-N
    2.1.4 Canonical SMILES
    C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
    2.1.5 Isomeric SMILES
    C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
    2.2 Other Identifiers
    2.2.1 UNII
    436LRU32H5
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 3r)-3-cyclopentyl-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)pyrazol-1-yl)propanenitrile

    2. Inc-424

    3. Inc424

    4. Inca24

    5. Incb-018424

    6. Incb-018424 Phosphate

    7. Incb-018424 Salt

    8. Incb-18424

    9. Incb-18424 Phosphate

    10. Incb018424

    11. Incb018424 Phosphate

    12. Jakafi

    13. Jakavi

    14. Opzelura

    15. Ruxolitinib

    16. Ruxolitinib (as Phosphate)

    17. Ruxolitinib Monophosphate

    2.3.2 Depositor-Supplied Synonyms

    1. 1092939-17-7

    2. Jakafi

    3. (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile Phosphate

    4. Jakavi

    5. Ruxolitinib (phosphate)

    6. Ruxolitinib Monophosphate

    7. Incb018424 Phosphate

    8. Ruxolitinib (as Phosphate)

    9. Incb-018424 Phosphate

    10. Incb-018424 Salt

    11. Ruxolitinib Phosphate [usan]

    12. Incb-18424 Phosphate

    13. Incb018424 Salt

    14. Chebi:66917

    15. 436lru32h5

    16. 1092939-17-7 (phosphate)

    17. (betar)-beta-cyclopentyl-4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazole-1-propanenitrile Phosphate

    18. Incb-18424

    19. Ruxolitinib Phosphate Salt

    20. (3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrile Phosphate

    21. (3r)-3-cyclopentyl-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)propanenitrile Phosphate (1:1)

    22. Phosphenoperoxoic Acid Compound With (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)- 1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile And Dihydrogen (1:1:1)

    23. Opzelura

    24. Unii-436lru32h5

    25. (3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrilephosphoricacid

    26. Jakafi (tn)

    27. Jakavi (tn)

    28. Ruxolitinib Phosphate(incb018424)

    29. Inc 424 Phosphate

    30. Incb 018424 Phosphate

    31. Incb-424

    32. Schembl1369365

    33. Chembl1795071

    34. Amy5620

    35. Dtxsid00911086

    36. Ruxolitinib Phosphate (jan/usan)

    37. Ruxolitinib Phosphate [mi]

    38. Ruxolitinib Phosphate [jan]

    39. Ex-a2660

    40. Cs1956

    41. Mfcd18452860

    42. S5243

    43. Akos024464417

    44. Ruxolitinib (incb-18424) Phosphate

    45. Ruxolitinib Phosphate [who-dd]

    46. Bcp9000783

    47. Ccg-268687

    48. Cs-0326

    49. 1h-pyrazole-1-propanenitrile, Beta-cyclopentyl-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-,(betar)-, Phosphate (1:1)

    50. Ac-30901

    51. As-74723

    52. Hy-50858

    53. Ruxolitinib Phosphate [orange Book]

    54. Ruxolitinib (as Phosphate) [ema Epar]

    55. D09960

    56. J-501793

    57. Q27135517

    58. (3r)-3-cyclopentyl-3-(4-{7h-pyrrolo[2,3-d]pyrimidin-4-yl}-1h-pyrazol-1-yl)propanenitrile; Phosphoric Acid

    59. (3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric Acid

    60. (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrilephosphate

    61. 1h-pyrazole-1-propanenitrile,.beta.-cyclopentyl-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-,(.beta.r)-,phosphate (1:1)

    62. Phosphoric Acid--3-cyclopentyl-3-[4-(1h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrile (1/1)

    2.4 Create Date
    2009-01-19
    3 Chemical and Physical Properties
    Molecular Weight 404.4 g/mol
    Molecular Formula C17H21N6O4P
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count4
    Exact Mass404.13619017 g/mol
    Monoisotopic Mass404.13619017 g/mol
    Topological Polar Surface Area161 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity503
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameJakafi
    PubMed HealthRuxolitinib (By mouth)
    Drug ClassesAntineoplastic Agent
    Active IngredientRuxolitinib phosphate
    Dosage FormTablet
    RouteOral
    Strengtheq 5mg base; eq 20mg base; eq 15mg base; eq 10mg base; eq 25mg base
    Market StatusPrescription
    CompanyIncyte

    2 of 2  
    Drug NameJakafi
    PubMed HealthRuxolitinib (By mouth)
    Drug ClassesAntineoplastic Agent
    Active IngredientRuxolitinib phosphate
    Dosage FormTablet
    RouteOral
    Strengtheq 5mg base; eq 20mg base; eq 15mg base; eq 10mg base; eq 25mg base
    Market StatusPrescription
    CompanyIncyte

    4.2 Drug Indication

    * Myelofibrosis (MF):

    Jakavi is indicated for the treatment of disease related splenomegaly or symptoms in adult patients with primary myelofibrosis (also known as chronic idiopathic myelofibrosis), post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis.

    * Polycythaemia vera (PV):

    Jakavi is indicated for the treatment of adult patients with polycythaemia vera who are resistant to or intolerant of hydroxyurea.

    * Graft versus host disease (GvHD):

    Jakavi is indicated for the treatment of patients aged 12 years and older with acute graft versus host disease or chronic graft versus host disease who have inadequate response to corticosteroids or other systemic therapies (see section 5. 1).

    Treatment of chronic Graft versus Host Disease (cGvHD)

    Treatment of acute graft-versus-host disease (aGvHD)

    Treatment of vitiligo

    5 Pharmacology and Biochemistry
    5.1 ATC Code

    L01EJ01

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AP","supplier":"MSN LABORATORIES PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"SEOUL - INCHEON INT\\'","customer":"BORYUNG CORP","customerCountry":"KOREA, REPUBLIC OF","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"37000","totalValueFC":"7251.3","currency":"USD","unitRateINR":3126385,"date":"18-Jan-2025","totalValueINR":"625277","totalValueInUsd":"7251.3","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"7394804","productDescription":"API","marketType":"REGULATED MARKET","country":"REPUBLIC OF KOREA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1737138600,"product":"RUXOLITINIB PHOSPHATE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"SEOUL - INCHEON INT\\'","customer":"SAMYANG HOLDINGS CORP","customerCountry":"KOREA, REPUBLIC OF","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"35000","totalValueFC":"6855.3","currency":"USD","unitRateINR":2955615,"date":"18-Jan-2025","totalValueINR":"591123","totalValueInUsd":"6855.3","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"7397504","productDescription":"API","marketType":"REGULATED MARKET","country":"REPUBLIC OF KOREA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1741199400,"product":"RUXOLITINIB PHOSPHATE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"TOKYO","customer":"ME PHARMACOLTD","customerCountry":"JAPAN","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"60000","totalValueFC":"5893.3","currency":"USD","unitRateINR":5104660,"date":"06-Mar-2025","totalValueINR":"510466","totalValueInUsd":"5893.3","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"8781957","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1742149800,"product":"RUXOLITINIB PHOSPHATE IH","address":"8-3-166\/7\/1, ERRAGADDA,,ERRAGADDA","city":"HYDERABAD,TELANGANA","supplier":"VALARY LAB PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"SANTO DOMINGO","customer":"LABORATORIOS SUED SRL","customerCountry":"DOMINICAN REPUBLIC","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"30000","totalValueFC":"29418.3","currency":"USD","unitRateINR":2548139,"date":"17-Mar-2025","totalValueINR":"2548139","totalValueInUsd":"29418.3","indian_port":"Hyderabad Air","hs_no":"29420090","bill_no":"9064111","productDescription":"API","marketType":"","country":"DOMINICAN REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"8-3-166\/7\/1, ERRAGADDA,,ERRAGADDA, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1742495400,"product":"RUXOLITINIB PHOSPHATE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"OSAKA","customer":"TOWA PHARMACEUTICAL CO LTD","customerCountry":"JAPAN","quantity":"0.30","actualQuantity":"0.3","unit":"KGS","unitRateFc":"60000","totalValueFC":"17772","currency":"USD","unitRateINR":5131230,"date":"21-Mar-2025","totalValueINR":"1539369","totalValueInUsd":"17772","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"9219508","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1742495400,"product":"RUXOLITINIB PHOSPHATE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"OSAKA","customer":"TOWA PHARMACEUTICAL CO LTD","customerCountry":"JAPAN","quantity":"3.50","actualQuantity":"3.5","unit":"KGS","unitRateFc":"60000","totalValueFC":"207460.2","currency":"USD","unitRateINR":5134200.2857142854,"date":"21-Mar-2025","totalValueINR":"17969701","totalValueInUsd":"207460.2","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"9219508","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744309800,"product":"RUXOLITINIB HEMIFUMARATE IH SPEC 1","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"DR REDDY'S LABORATORIES","supplierCountry":"INDIA","foreign_port":"SEOUL - INCHEON INT\\'","customer":"DAEWOONG PHARMACEUTICAL CO LTD","customerCountry":"KOREA, REPUBLIC OF","quantity":"7.74","actualQuantity":"7.743","unit":"KGS","unitRateFc":"20500","totalValueFC":"157271.8","currency":"USD","unitRateINR":1738699.4795298979,"date":"11-Apr-2025","totalValueINR":"13462750.07","totalValueInUsd":"157271.8","indian_port":"Hyderabad Air","hs_no":"29420090","bill_no":"9882686","productDescription":"API","marketType":"REGULATED MARKET","country":"REPUBLIC OF KOREA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE, HYDERABAD ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1748370600,"product":"RUXOLITINIB PHOSPHATE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"OSAKA","customer":"TOWA PHARMACEUTICAL CO LTD","customerCountry":"JAPAN","quantity":"2.80","actualQuantity":"2.8","unit":"KGS","unitRateFc":"60000","totalValueFC":"166931.8","currency":"USD","unitRateINR":5079535,"date":"28-May-2025","totalValueINR":"14222698","totalValueInUsd":"166931.8","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"2215060","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1652985000,"product":"RUXOLITINIB (PHOSPHATE)","address":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK","city":"KURLA, MUMBAI","supplier":"MEDCHEMEXPRESS LLC","supplierCountry":"UNITED STATES","foreign_port":"N\/A","customer":"PIRAMAL PHARMA LTD","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"5","unit":"GMS","unitRateFc":"557.2","totalValueFC":"2833.3","currency":"USD","unitRateINR":"43794","date":"20-May-2022","totalValueINR":"218970","totalValueInUsd":"2833.3","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29420090","bill_no":"1002030","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"18 WILKINSON WAY, PRINCETON, NJ 08540 UNITED STATES","customerAddress":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1673548200,"product":"RUXOLITINIB PHOSPHATE DS.014 [INC424 DRUG SUBSTANCE]","address":"INSPIRE BKC PART OF 601 AND 701,BA NDRAKURLA COMPLEX BANDRA EAST","city":"MUMBAI,MAHARASHTRA","supplier":"NOVARTIS PHARMA AG BASEL","supplierCountry":"SWITZERLAND","foreign_port":"NA","customer":"NOVARTIS HEALTHCARE PRIVATE LTD","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2000","unit":"GMS","unitRateFc":"1091.8","totalValueFC":"2425871","currency":"CHF","unitRateINR":"99169","date":"13-Jan-2023","totalValueINR":"198337913.1","totalValueInUsd":"2425871","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"4172789","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"INSPIRE BKC PART OF 601 AND 701,BA NDRAKURLA COMPLEX BANDRA EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1683916200,"product":"RUXOLITINIB (PHOSPHATE)","address":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK","city":"KURLA, MUMBAI","supplier":"MEDCHEMEXPRESS LLC","supplierCountry":"UNITED STATES","foreign_port":"N\/A","customer":"PIRAMAL PHARMA LTD","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"10","unit":"GMS","unitRateFc":"545.1","totalValueFC":"5471.5","currency":"USD","unitRateINR":"45022.2","date":"13-May-2023","totalValueINR":"450222","totalValueInUsd":"5471.5","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29334900","bill_no":"1002007","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"1 DEERPARK DR STE Q PRINCETON, NJ 08852","customerAddress":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK"}]
    18-Jan-2022
    28-May-2025
    KGS
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    INTERMEDIATE SUPPLIERS

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    01

    Shandong Chenghui Shuangda Pharmace...

    China
    HPAPI Summit
    Not Confirmed
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    • fda
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    Virtual BoothChina's leading API and intermediate manufacturer, offering CMO/CDMO services and exports to 70+ countries, enhancing global health.

    1-(1-ethoxyethyl)-4-(4,4,5,5- tetramethyl-1,3,2-di...

    CAS Number : 1029716-44-6

    End Use API : Ruxolitinib Phosphate

    About The Company : Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. is specialized in R&D and production of APIs and advanced intermediates. With 22 years of production experie...

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    02

    Shandong Chenghui Shuangda Pharmace...

    China
    HPAPI Summit
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    Virtual BoothChina's leading API and intermediate manufacturer, offering CMO/CDMO services and exports to 70+ countries, enhancing global health.

    3-Cyclopentylacrylonitrile

    CAS Number : 591769-05-0

    End Use API : Ruxolitinib Phosphate

    About The Company : Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. is specialized in R&D and production of APIs and advanced intermediates. With 22 years of production experie...

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    03

    Shandong Chenghui Shuangda Pharmace...

    China
    HPAPI Summit
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    Virtual BoothChina's leading API and intermediate manufacturer, offering CMO/CDMO services and exports to 70+ countries, enhancing global health.

    (4-(1-(2-Cyano-1- cyclopentylethyl)-1h-pyrazol-4-y...

    CAS Number : 1236033-05-8

    End Use API : Ruxolitinib Phosphate

    About The Company : Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. is specialized in R&D and production of APIs and advanced intermediates. With 22 years of production experie...

    Shandong Chenghui Shuangda Pharmaceutical

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    04

    Hangzhou Allsino Chemicals

    China
    HPAPI Summit
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    • fda
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    Virtual BoothAllsino Pharma excels in R&D & manufacturing of RSMs, GMP intermediates, & APIs; ISO-certified, GMP-compliant, accredited by NMPA.

    1-(1-Ethoxyethyl)-4-(4,4,5,5-tetramethyl[1,3,2]dio...

    CAS Number : 1029716-44-6

    End Use API : Ruxolitinib Phosphate

    About The Company : Allsino Pharmaceutical, established in May 2004, spans 97,350m² and specializes in the R&D and manufacturing of RSMs, GMP intermediates, and APIs. Our products...

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    05

    Hangzhou Allsino Chemicals

    China
    HPAPI Summit
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    Virtual BoothAllsino Pharma excels in R&D & manufacturing of RSMs, GMP intermediates, & APIs; ISO-certified, GMP-compliant, accredited by NMPA.

    4-Chloro-7H-pyrrolo-[2,3-d]pyrimidine

    CAS Number : 3680-69-1

    End Use API : Ruxolitinib Phosphate

    About The Company : Allsino Pharmaceutical, established in May 2004, spans 97,350m² and specializes in the R&D and manufacturing of RSMs, GMP intermediates, and APIs. Our products...

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    06

    Hangzhou Allsino Chemicals

    China
    HPAPI Summit
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    Virtual BoothAllsino Pharma excels in R&D & manufacturing of RSMs, GMP intermediates, & APIs; ISO-certified, GMP-compliant, accredited by NMPA.

    4-Methyl-7-H-pyrrolo[2,3-d]pyrimidine

    CAS Number : 945950-37-8

    End Use API : Ruxolitinib Phosphate

    About The Company : Allsino Pharmaceutical, established in May 2004, spans 97,350m² and specializes in the R&D and manufacturing of RSMs, GMP intermediates, and APIs. Our products...

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    07

    Almelo

    India
    HPAPI Summit
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    Almelo

    India
    HPAPI Summit
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    3,7-Dihydro-4H-Pyrrolo[2,3-d] Pyrimidin-4-One

    CAS Number : CAS-3680-71-5

    End Use API : Ruxolitinib Phosphate

    About The Company : Almelo are the industry leaders in manufacturing advanced intermediates, Active Pharmaceutical Ingredients (APIs) and specialty fine chemicals. With a diverse p...

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    08

    Ami Organics Private Limited

    India
    HPAPI Summit
    Not Confirmed
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    Ami Organics Private Limited

    India
    HPAPI Summit
    Not Confirmed
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    3-CYCLOPENTYL ACRYLONITRILE

    CAS Number : 591769-05-0

    End Use API : Ruxolitinib Phosphate

    About The Company : Founded with a mission to transform strategic capital into specialty chemicals, Ami Group focuses on Agrochemicals, Cosmetics, and Polymers. Ami Organics Ltd. i...

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    09

    Ami Organics Private Limited

    India
    HPAPI Summit
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    Ami Organics Private Limited

    India
    HPAPI Summit
    Not Confirmed
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    4,6-DIHYDROXY PYRIMIDINE

    CAS Number : 1193-24-4

    End Use API : Ruxolitinib Phosphate

    About The Company : Founded with a mission to transform strategic capital into specialty chemicals, Ami Group focuses on Agrochemicals, Cosmetics, and Polymers. Ami Organics Ltd. i...

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    10

    Ami Organics Private Limited

    India
    HPAPI Summit
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    Ami Organics Private Limited

    India
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    Not Confirmed
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    4-BROMO-1H-PYRAZOLE

    CAS Number : 2075-45-8

    End Use API : Ruxolitinib Phosphate

    About The Company : Founded with a mission to transform strategic capital into specialty chemicals, Ami Group focuses on Agrochemicals, Cosmetics, and Polymers. Ami Organics Ltd. i...

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    Only 10 entries up to this point, click to access all click full view read-more
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    Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

    FDF Dossiers

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    01

    NanoAlvand

    Iran
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    CPhI WW Frankfurt
    Attending
    • fda
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    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

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    Regulatory Info :

    Registration Country : Iran

    Ruxolitinib Phosphate

    Brand Name : Relata

    Dosage Form : Tablet

    Dosage Strength : 5MG

    Packaging :

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    Application Number :

    Regulatory Info :

    Registration Country : Iran

    NanoAlvand

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    02

    NanoAlvand

    Iran
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    Attending
    • fda
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    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

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    Regulatory Info :

    Registration Country : Iran

    Ruxolitinib Phosphate

    Brand Name : Relata

    Dosage Form : Tablet

    Dosage Strength : 10MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Iran

    NanoAlvand

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    03

    NanoAlvand

    Iran
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    Attending
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    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

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    Flag Iran
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    Regulatory Info :

    Registration Country : Iran

    Ruxolitinib Phosphate

    Brand Name : Relata

    Dosage Form : Tablet

    Dosage Strength : 15MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Iran

    NanoAlvand

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    04

    NanoAlvand

    Iran
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    CPhI WW Frankfurt
    Attending
    • fda
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    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

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    Flag Iran
    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : Iran

    Ruxolitinib Phosphate

    Brand Name : Relata

    Dosage Form : Tablet

    Dosage Strength : 20MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Iran

    NanoAlvand

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    05

    Granules India Limited

    India
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    CPhI WW Frankfurt
    Booth #H9.1A48
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    Virtual BoothGranules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

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    Regulatory Info :

    Registration Country : India

    Ruxolitinib Phosphate

    Brand Name : Ruxolitinib Phosphate

    Dosage Form : Immediate Release Tablet

    Dosage Strength : 4.71%

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Granules India

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    06

    Medichem S.A

    Spain
    HPAPI Summit
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    Medichem S.A

    Spain
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    Regulatory Info :

    Registration Country : Spain

    Ruxolitinib Phosphate

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 2MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Spain

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    07

    Novartis Pharmaceuticals Corporatio...

    Switzerland
    HPAPI Summit
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    Novartis Pharmaceuticals Corporatio...

    Switzerland
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    HPAPI Summit
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    Ruxolitinib

    Brand Name : Jakavi

    Dosage Form : Tablet

    Dosage Strength : 15mg

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    Registration Country : Switzerland

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    Novartis Pharmaceuticals Corporatio...

    Switzerland
    HPAPI Summit
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    Novartis Pharmaceuticals Corporatio...

    Switzerland
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    HPAPI Summit
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    Ruxolitinib phosphate

    Brand Name : Jakavi 20 mg

    Dosage Form : TAB

    Dosage Strength : 20mg

    Packaging : 56X1mg

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    Regulatory Info : Originator

    Registration Country : South Africa

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    09

    Novartis Pharmaceuticals Corporatio...

    Switzerland
    HPAPI Summit
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    Novartis Pharmaceuticals Corporatio...

    Switzerland
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    HPAPI Summit
    Not Confirmed
    • fda
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Regulatory Info :

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    Ruxolitinib

    Brand Name : Jakavi

    Dosage Form :

    Dosage Strength :

    Packaging : 56

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    Application Number :

    Regulatory Info :

    Registration Country : Australia

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    10

    Novartis Pharmaceuticals Corporatio...

    Switzerland
    HPAPI Summit
    Not Confirmed
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    Novartis Pharmaceuticals Corporatio...

    Switzerland
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    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Regulatory Info :

    Registration Country : Australia

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    Europe

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    01

    Novartis Pharma Schweiz AG

    Switzerland
    HPAPI Summit
    Not Confirmed
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    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Switzerland
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Switzerland

    Ruxolitinib

    Brand Name : Jakavi

    Dosage Form : Tablet

    Dosage Strength : 10mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

    blank

    Portfolio PDF

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    02

    Novartis Pharma Schweiz AG

    Switzerland
    HPAPI Summit
    Not Confirmed
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    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Switzerland
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Switzerland

    Ruxolitinib

    Brand Name : Jakavi

    Dosage Form : Tablet

    Dosage Strength : 15mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

    blank

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    03

    Novartis Pharma Schweiz AG

    Switzerland
    HPAPI Summit
    Not Confirmed
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    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : Switzerland

    Ruxolitinib

    Brand Name : Jakavi

    Dosage Form : Tablet

    Dosage Strength : 20mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

    blank

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    04

    Novartis Pharma Schweiz AG

    Switzerland
    HPAPI Summit
    Not Confirmed
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    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Regulatory Info :

    Registration Country : Switzerland

    Ruxolitinib

    Brand Name : Jakavi

    Dosage Form : Tablet

    Dosage Strength : 5mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    05

    Orifarm AS

    Denmark
    HPAPI Summit
    Not Confirmed
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    Orifarm AS

    Denmark
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    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Norway

    Ruxolitinib Phosphate

    Brand Name : Jakavi

    Dosage Form : Antic-calc Tablet

    Dosage Strength : 15 mg

    Packaging : Blister

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

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    06

    Orifarm AS

    Denmark
    HPAPI Summit
    Not Confirmed
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    Orifarm AS

    Denmark
    arrow
    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Norway

    Ruxolitinib Phosphate

    Brand Name : Jakavi

    Dosage Form : Antic-calc Tablet

    Dosage Strength : 20 mg

    Packaging : Blister

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

    blank

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    07

    Orifarm AS

    Denmark
    HPAPI Summit
    Not Confirmed
    arrow

    Orifarm AS

    Denmark
    arrow
    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Denmark
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Norway

    Ruxolitinib Phosphate

    Brand Name : Jakavi

    Dosage Form : Antic-calc Tablet

    Dosage Strength : 5 mg

    Packaging : Blister

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

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    01

    NanoAlvand

    Iran
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    CPhI WW Frankfurt
    Attending
    • fda
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    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

    Contact Supplier Contact Supplier
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    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : Iran

    Ruxolitinib Phosphate

    Brand Name : Relata

    Dosage Form : Tablet

    Dosage Strength : 5MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Iran

    NanoAlvand

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    01

    NanoAlvand

    Iran
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

    Contact Supplier Contact Supplier
    Flag Iran
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Ruxolitinib Phosphate

    Dosage : Tablet

    Dosage Strength : 5MG

    Brand Name : Relata

    Approval Date :

    Application Number :

    Registration Country : Iran

    NanoAlvand

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    02

    NanoAlvand

    Iran
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

    Contact Supplier Contact Supplier
    Flag Iran
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Iran

    Ruxolitinib Phosphate

    Brand Name : Relata

    Dosage Form : Tablet

    Dosage Strength : 10MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Iran

    NanoAlvand

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    02

    NanoAlvand

    Iran
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

    Contact Supplier Contact Supplier
    Flag Iran
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Ruxolitinib Phosphate

    Dosage : Tablet

    Dosage Strength : 10MG

    Brand Name : Relata

    Approval Date :

    Application Number :

    Registration Country : Iran

    NanoAlvand

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    03

    NanoAlvand

    Iran
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

    Contact Supplier Contact Supplier
    Flag Iran
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Iran

    Ruxolitinib Phosphate

    Brand Name : Relata

    Dosage Form : Tablet

    Dosage Strength : 15MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Iran

    NanoAlvand

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

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    03

    NanoAlvand

    Iran
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

    Contact Supplier Contact Supplier
    Flag Iran
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Ruxolitinib Phosphate

    Dosage : Tablet

    Dosage Strength : 15MG

    Brand Name : Relata

    Approval Date :

    Application Number :

    Registration Country : Iran

    NanoAlvand

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    04

    NanoAlvand

    Iran
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

    Contact Supplier Contact Supplier
    Flag Iran
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Iran

    Ruxolitinib Phosphate

    Brand Name : Relata

    Dosage Form : Tablet

    Dosage Strength : 20MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Iran

    NanoAlvand

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

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    Corporate PDF

    04

    NanoAlvand

    Iran
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanoAlvand is the entrance to Global Markets as a trusted Highly Potent Products manufacturer.

    Contact Supplier Contact Supplier
    Flag Iran
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Ruxolitinib Phosphate

    Dosage : Tablet

    Dosage Strength : 20MG

    Brand Name : Relata

    Approval Date :

    Application Number :

    Registration Country : Iran

    NanoAlvand

    Portfolio PDF

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    05

    Granules India Limited

    India
    arrow
    CPhI WW Frankfurt
    Booth #H9.1A48
    • fda
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    Virtual BoothGranules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

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    Regulatory Info :

    Registration Country : India

    Ruxolitinib Phosphate

    Brand Name : Ruxolitinib Phosphate

    Dosage Form : Immediate Release Tabl...

    Dosage Strength : 4.71%

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : India

    Granules India

    Portfolio PDF

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    05

    Granules India Limited

    India
    arrow
    CPhI WW Frankfurt
    Booth #H9.1A48
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothGranules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

    Contact Supplier Contact Supplier
    Flag India
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Packaging :

    Regulatory Info :

    Ruxolitinib Phosphate

    Dosage : Immediate Release Tabl...

    Dosage Strength : 4.71%

    Brand Name : Ruxolitinib Phosphate

    Approval Date :

    Application Number :

    Registration Country : India

    Granules India

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    06

    Medichem S.A

    Spain
    HPAPI Summit
    Not Confirmed
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    Medichem S.A

    Spain
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    HPAPI Summit
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    Regulatory Info :

    Registration Country : Spain

    Ruxolitinib Phosphate

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 2MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Spain

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    06

    Medichem S.A

    Spain
    HPAPI Summit
    Not Confirmed
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    07

    Medichem S.A

    Spain
    HPAPI Summit
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    Medichem S.A

    Spain
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    HPAPI Summit
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    • fda
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag Spain
    Virtual Booth Virtual Booth
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    Regulatory Info :

    Registration Country : Spain

    Ruxolitinib Phosphate

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 10MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Spain

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    07

    Medichem S.A

    Spain
    HPAPI Summit
    Not Confirmed
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    08

    Medichem S.A

    Spain
    HPAPI Summit
    Not Confirmed
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    Medichem S.A

    Spain
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    HPAPI Summit
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    • fda
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Regulatory Info :

    Registration Country : Spain

    Ruxolitinib Phosphate

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 15MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Spain

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    08

    Medichem S.A

    Spain
    HPAPI Summit
    Not Confirmed
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    09

    Medichem S.A

    Spain
    HPAPI Summit
    Not Confirmed
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    Medichem S.A

    Spain
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    HPAPI Summit
    Not Confirmed
    • fda
    • EDQM
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Regulatory Info :

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    Ruxolitinib Phosphate

    Brand Name :

    Dosage Form : Tablet

    Dosage Strength : 20MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Spain

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    09

    Medichem S.A

    Spain
    HPAPI Summit
    Not Confirmed
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    10

    Medichem S.A

    Spain
    HPAPI Summit
    Not Confirmed
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    Medichem S.A

    Spain
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    HPAPI Summit
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Ruxolitinib Phosphate

    Brand Name :

    Dosage Form : Cream

    Dosage Strength : 1.5%

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Spain

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    Spain
    HPAPI Summit
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    01

    Brand Name : Jakavi

    Ruxolitinib

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    Brand Name : Jakavi

    Switzerland
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    HPAPI Summit
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    Novartis

    Ruxolitinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2020 Revenue in Millions : 1,339

    2019 Revenue in Millions : 1,114

    Growth (%) : 20

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    Brand Name : Jakavi

    Ruxolitinib

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    Brand Name : Jakavi

    Switzerland
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    HPAPI Summit
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    Novartis

    Ruxolitinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2021 Revenue in Millions : 1,595

    2020 Revenue in Millions : 1,339

    Growth (%) : 19

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    03

    Brand Name : Jakavi

    Ruxolitinib

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    HPAPI Summit
    Not Confirmed

    Brand Name : Jakavi

    Switzerland
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    HPAPI Summit
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    Novartis

    Ruxolitinib

    Main Therapeutic Indication : Hematology

    Currency : USD

    2022 Revenue in Millions : 1,561

    2021 Revenue in Millions : 1,595

    Growth (%) : -2

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    Novartis

    Ruxolitinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2023 Revenue in Millions : 1,720

    2022 Revenue in Millions : 1,561

    Growth (%) : 10

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    Novartis

    Ruxolitinib

    Main Therapeutic Indication : Oncology

    Currency : USD

    2024 Revenue in Millions : 1,936

    2023 Revenue in Millions : 1,720

    Growth (%) : 13

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    Novartis

    Ruxolitinib Phosphate

    Main Therapeutic Indication : Oncology

    Currency : USD

    2014 Revenue in Millions : 71.20%

    2013 Revenue in Millions :

    Growth (%) :

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    Novartis

    Ruxolitinib Phosphate

    Main Therapeutic Indication : Oncology

    Currency : USD

    2015 Revenue in Millions : 279

    2014 Revenue in Millions : 410

    Growth (%) : 47%

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    Novartis

    Ruxolitinib Phosphate

    Main Therapeutic Indication : Oncology

    Currency : USD

    2016 Revenue in Millions : 581

    2015 Revenue in Millions : 410

    Growth (%) : 42

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    Novartis

    Ruxolitinib Phosphate

    Main Therapeutic Indication : Oncology

    Currency : USD

    2017 Revenue in Millions : 777

    2016 Revenue in Millions : 581

    Growth (%) : 34

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    Novartis

    Ruxolitinib Phosphate

    Main Therapeutic Indication : Oncology

    Currency : USD

    2018 Revenue in Millions : 977

    2017 Revenue in Millions : 777

    Growth (%) : 26%

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    APIs

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    Israel.png
    Ruxolitinib Phosphate (500 g - 1 kg) API needed in Israel [ENA22740]
    A CRO that focuses on the development of various finished formulations is looking for suppliers of Ruxolitinib Phosphate (500 g - 1 kg) API for development purposes. The suppliers must support this enquiry with CEP/ USDMF & CoA.
    22 Apr 2025

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    22 Apr 2025

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    22 Apr 2025

    turkeypng-1602828403png-1622460951png-1622462103.png
    Ruxolitinib Phosphate (15 kg) API needed in Turkey [ENA22182]
    A company that focuses on development and manufacturing of various finished formulations is looking for suppliers of Ruxolitinib Phosphate (15 kg) API for commercial purposes. The suppliers must support this enquiry with CEP, DMF, GMP & CoA.
    24 Feb 2025

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    24 Feb 2025

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    24 Feb 2025

    india-flag.png
    Ruxolitinib Phosphate (100 g) API needed in India [ENA20371]
    A company that focuses on development and manufacturing of various liquids, ointments, and personal care product is looking for suppliers of Ruxolitinib Phosphate (100 g) API for development purposes. The suppliers must support this enquiry with DMF & CoA.
    27 Aug 2024

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    27 Aug 2024

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    27 Aug 2024

    india-flag.png
    Ruxolitinib Phosphate (1 kg) API needed in India [ENA20350]
    A company that focuses on development and manufacturing of various finished formulations is looking for suppliers of Ruxolitinib Phosphate (1 kg) API for development purposes. The suppliers must support this enquiry with CoA.
    24 Aug 2024

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    24 Aug 2024

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    24 Aug 2024

    india-flag.png
    Ruxolitinib Phosphate API needed in India [ENA20193]
    A company that focuses on manufacturing of various injectables, tablets, capsules, syrups, eye drops & ointments is looking for suppliers of Ruxolitinib Phosphate API. The required quantity is 200 g for evaluation and 5 kg - 50 kg for commercial purposes. The suppliers must support this enquiry with DMF & CoA.
    05 Aug 2024

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    05 Aug 2024

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    05 Aug 2024

    Taiwan.png
    Ruxolitinib Phosphate (MOQ) API needed in Taiwan [ENA19951]
    A biopharmaceutical company that focuses on development of topical new dosage form and non-viral gene delivery systems is looking for suppliers of Ruxolitinib Phosphate (MOQ) API for development purposes. The suppliers must support this enquiry with CoA.
    12 Jul 2024

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    12 Jul 2024

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    12 Jul 2024

    india-flag.png
    Ruxolitinib Phosphate (1 kg) API needed in India [ENA19775]
    A CRO that provides formulation and analytical development services for OSDs, parenteral and liquid orals is looking for suppliers of Ruxolitinib Phosphate (1 kg) API for both development & commercial purposes. The suppliers must support this enquiry with CEP/ USDMF & CoA.
    22 Jun 2024

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    22 Jun 2024

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    22 Jun 2024

    Tunisia.png
    Ruxolitinib API needed in Tunisia [ENA18201]
    A company that deals in various pharmaceutical products is looking for suppliers of Ruxolitinib API. The initial required quantity is 300 g for development & 2 kg for commercial purposes. The suppliers must support this enquiry with CoA.
    02 Oct 2023

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    02 Oct 2023

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    02 Oct 2023

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    Ruxolitinib Phosphate & Nilotinib APIs needed in India [ENA17533]
    A company based in India that focuses on the research, development and manufacturing of complex pharmaceutical products including solid oral dosages, topicals, injectables & ophthalmics is looking for suppliers of Ruxolitinib Phosphate & Nilotinib APIs for both development & commercial purposes. The suppliers must support this enquiry with open part DMF & CoA.
    12 Jul 2023

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    12 Jul 2023

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    12 Jul 2023

    Israel.png
    Ruxolitinib Phosphate (10 g) API needed in Israel [ENA16243]
    A company that focuses on the research and development of ophthalmology drugs is looking for suppliers of Ruxolitinib Phosphate (10 g) API for development purposes. The suppliers must support this enquiry with CoA.
    30 Jan 2023

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    30 Jan 2023

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    30 Jan 2023

    Only 10 entries up to this point, click to access all click full view read-more
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    Patents & EXCLUSIVITIES

    Check the patents & exclusivity for this product

    US Patents

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    01

    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    INCYTE CORP

    U.S.A
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    Not Confirmed

    Patent Expiration Date : 2027-12-24

    RUXOLITINIB PHOSPHATE

    US Patent Number : 7598257

    Drug Substance Claim : Y

    Drug Product Claim : Y

    Application Number : 202192

    Patent Use Code : U-3227

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2027-12-24

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    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    INCYTE CORP

    U.S.A
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    Not Confirmed

    Patent Expiration Date : 2028-06-12

    RUXOLITINIB PHOSPHATE

    US Patent Number : 8829013

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 202192

    Patent Use Code : U-1201

    Delist Requested :

    Patent Use Description : FOR THE TREATMENT OF I...

    Patent Expiration Date : 2028-06-12

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    03

    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    INCYTE CORP

    U.S.A
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    Not Confirmed

    Patent Expiration Date : 2028-12-12

    RUXOLITINIB PHOSPHATE

    US Patent Number : 8822481*PED

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 202192

    Patent Use Code :

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2028-12-12

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    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    INCYTE CORP

    U.S.A
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    Not Confirmed

    Patent Expiration Date : 2027-12-24

    RUXOLITINIB PHOSPHATE

    US Patent Number : 7598257

    Drug Substance Claim : Y

    Drug Product Claim : Y

    Application Number : 202192

    Patent Use Code : U-3227

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2027-12-24

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    05

    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    INCYTE CORP

    U.S.A
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    HPAPI Summit
    Not Confirmed

    Patent Expiration Date : 2028-12-12

    RUXOLITINIB PHOSPHATE

    US Patent Number : 10610530*PED

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 215309

    Patent Use Code :

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2028-12-12

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    06

    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    Not Confirmed

    INCYTE CORP

    U.S.A
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    Not Confirmed

    Patent Expiration Date : 2028-06-12

    RUXOLITINIB PHOSPHATE

    US Patent Number : 10610530

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 215309

    Patent Use Code : U-3229

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2028-06-12

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    07

    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    Not Confirmed

    INCYTE CORP

    U.S.A
    arrow
    HPAPI Summit
    Not Confirmed

    Patent Expiration Date : 2026-12-12

    RUXOLITINIB PHOSPHATE

    US Patent Number : 9079912

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 202192

    Patent Use Code : U-3227

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2026-12-12

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    08

    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    Not Confirmed

    INCYTE CORP

    U.S.A
    arrow
    HPAPI Summit
    Not Confirmed

    Patent Expiration Date : 2031-11-20

    RUXOLITINIB PHOSPHATE

    US Patent Number : 11219624*PED

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 215309

    Patent Use Code :

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2031-11-20

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    09

    INCYTE CORP

    RUXOLITINIB PHOSPHATE

    arrow
    HPAPI Summit
    Not Confirmed

    INCYTE CORP

    U.S.A
    arrow
    HPAPI Summit
    Not Confirmed

    Patent Expiration Date : 2026-12-12

    RUXOLITINIB PHOSPHATE

    US Patent Number : 9079912

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 215309

    Patent Use Code : U-3404

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2026-12-12

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    10

    INCYTE CORP

    RUXOLITINIB PHOSPHATE

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    Not Confirmed

    INCYTE CORP

    U.S.A
    arrow
    HPAPI Summit
    Not Confirmed

    Patent Expiration Date : 2028-06-12

    RUXOLITINIB PHOSPHATE

    US Patent Number : 8829013

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 202192

    Patent Use Code : U-3228

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2028-06-12

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    ABOUT THIS PAGE

    Looking for 1092939-17-7 / Ruxolitinib Phosphate API manufacturers, exporters & distributors?

    Ruxolitinib Phosphate manufacturers, exporters & distributors 1

    41

    PharmaCompass offers a list of Ruxolitinib Phosphate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ruxolitinib Phosphate manufacturer or Ruxolitinib Phosphate supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ruxolitinib Phosphate manufacturer or Ruxolitinib Phosphate supplier.

    PharmaCompass also assists you with knowing the Ruxolitinib Phosphate API Price utilized in the formulation of products. Ruxolitinib Phosphate API Price is not always fixed or binding as the Ruxolitinib Phosphate Price is obtained through a variety of data sources. The Ruxolitinib Phosphate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Ruxolitinib Phosphate

    Synonyms

    1092939-17-7, Jakafi, (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate, Jakavi, Ruxolitinib (phosphate), Ruxolitinib monophosphate

    Cas Number

    1092939-17-7

    Unique Ingredient Identifier (UNII)

    436LRU32H5

    About Ruxolitinib Phosphate

    Ruxolitinib Phosphate is the phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.

    Ruxolitinib phosphate (JAN/USAN) Manufacturers

    A Ruxolitinib phosphate (JAN/USAN) manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ruxolitinib phosphate (JAN/USAN), including repackagers and relabelers. The FDA regulates Ruxolitinib phosphate (JAN/USAN) manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ruxolitinib phosphate (JAN/USAN) API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Ruxolitinib phosphate (JAN/USAN) manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Ruxolitinib phosphate (JAN/USAN) Suppliers

    A Ruxolitinib phosphate (JAN/USAN) supplier is an individual or a company that provides Ruxolitinib phosphate (JAN/USAN) active pharmaceutical ingredient (API) or Ruxolitinib phosphate (JAN/USAN) finished formulations upon request. The Ruxolitinib phosphate (JAN/USAN) suppliers may include Ruxolitinib phosphate (JAN/USAN) API manufacturers, exporters, distributors and traders.

    click here to find a list of Ruxolitinib phosphate (JAN/USAN) suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Ruxolitinib phosphate (JAN/USAN) USDMF

    A Ruxolitinib phosphate (JAN/USAN) DMF (Drug Master File) is a document detailing the whole manufacturing process of Ruxolitinib phosphate (JAN/USAN) active pharmaceutical ingredient (API) in detail. Different forms of Ruxolitinib phosphate (JAN/USAN) DMFs exist exist since differing nations have different regulations, such as Ruxolitinib phosphate (JAN/USAN) USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Ruxolitinib phosphate (JAN/USAN) DMF submitted to regulatory agencies in the US is known as a USDMF. Ruxolitinib phosphate (JAN/USAN) USDMF includes data on Ruxolitinib phosphate (JAN/USAN)'s chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ruxolitinib phosphate (JAN/USAN) USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Ruxolitinib phosphate (JAN/USAN) suppliers with USDMF on PharmaCompass.

    Ruxolitinib phosphate (JAN/USAN) KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Ruxolitinib phosphate (JAN/USAN) Drug Master File in Korea (Ruxolitinib phosphate (JAN/USAN) KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Ruxolitinib phosphate (JAN/USAN). The MFDS reviews the Ruxolitinib phosphate (JAN/USAN) KDMF as part of the drug registration process and uses the information provided in the Ruxolitinib phosphate (JAN/USAN) KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Ruxolitinib phosphate (JAN/USAN) KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Ruxolitinib phosphate (JAN/USAN) API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Ruxolitinib phosphate (JAN/USAN) suppliers with KDMF on PharmaCompass.

    Ruxolitinib phosphate (JAN/USAN) WC

    A Ruxolitinib phosphate (JAN/USAN) written confirmation (Ruxolitinib phosphate (JAN/USAN) WC) is an official document issued by a regulatory agency to a Ruxolitinib phosphate (JAN/USAN) manufacturer, verifying that the manufacturing facility of a Ruxolitinib phosphate (JAN/USAN) active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Ruxolitinib phosphate (JAN/USAN) APIs or Ruxolitinib phosphate (JAN/USAN) finished pharmaceutical products to another nation, regulatory agencies frequently require a Ruxolitinib phosphate (JAN/USAN) WC (written confirmation) as part of the regulatory process.

    click here to find a list of Ruxolitinib phosphate (JAN/USAN) suppliers with Written Confirmation (WC) on PharmaCompass.

    Ruxolitinib phosphate (JAN/USAN) NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Ruxolitinib phosphate (JAN/USAN) as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Ruxolitinib phosphate (JAN/USAN) API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Ruxolitinib phosphate (JAN/USAN) as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Ruxolitinib phosphate (JAN/USAN) and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Ruxolitinib phosphate (JAN/USAN) NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Ruxolitinib phosphate (JAN/USAN) suppliers with NDC on PharmaCompass.

    Ruxolitinib phosphate (JAN/USAN) GMP

    Ruxolitinib phosphate (JAN/USAN) Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Ruxolitinib phosphate (JAN/USAN) GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ruxolitinib phosphate (JAN/USAN) GMP manufacturer or Ruxolitinib phosphate (JAN/USAN) GMP API supplier for your needs.

    Ruxolitinib phosphate (JAN/USAN) CoA

    A Ruxolitinib phosphate (JAN/USAN) CoA (Certificate of Analysis) is a formal document that attests to Ruxolitinib phosphate (JAN/USAN)'s compliance with Ruxolitinib phosphate (JAN/USAN) specifications and serves as a tool for batch-level quality control.

    Ruxolitinib phosphate (JAN/USAN) CoA mostly includes findings from lab analyses of a specific batch. For each Ruxolitinib phosphate (JAN/USAN) CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Ruxolitinib phosphate (JAN/USAN) may be tested according to a variety of international standards, such as European Pharmacopoeia (Ruxolitinib phosphate (JAN/USAN) EP), Ruxolitinib phosphate (JAN/USAN) JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ruxolitinib phosphate (JAN/USAN) USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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