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    Chemistry

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    Also known as: Polymyxin b, sulfate (salt), 1405-20-5, Polymixin b sulphate, Ks-1428, Pmb, Akos025392172
    Molecular Formula
    C56H100N16O17S
    Molecular Weight
    1301.6  g/mol
    InChI Key
    HFMDLUQUEXNBOP-OLYKAHIFSA-N
    Polymyxin B Sulfate
    1 2D Structure

    Polymyxin B Sulfate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;sulfuric acid
    2.1.2 InChI
    InChI=1S/C56H98N16O13.H2O4S/c1-7-32(4)13-11-12-16-44(75)63-36(17-23-57)51(80)72-46(34(6)74)56(85)68-39(20-26-60)48(77)67-41-22-28-62-55(84)45(33(5)73)71-52(81)40(21-27-61)65-47(76)37(18-24-58)66-53(82)42(29-31(2)3)69-54(83)43(30-35-14-9-8-10-15-35)70-49(78)38(19-25-59)64-50(41)79;1-5(2,3)4/h8-10,14-15,31-34,36-43,45-46,73-74H,7,11-13,16-30,57-61H2,1-6H3,(H,62,84)(H,63,75)(H,64,79)(H,65,76)(H,66,82)(H,67,77)(H,68,85)(H,69,83)(H,70,78)(H,71,81)(H,72,80);(H2,1,2,3,4)/t32?,33-,34-,36+,37+,38-,39+,40+,41+,42+,43-,45+,46+;/m1./s1
    2.1.3 InChI Key
    HFMDLUQUEXNBOP-OLYKAHIFSA-N
    2.1.4 Canonical SMILES
    CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O
    2.1.5 Isomeric SMILES
    CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)[C@@H](C)O.OS(=O)(=O)O
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. Polymyxin B, Sulfate (salt)

    2. 1405-20-5

    3. Polymixin B Sulphate

    4. Ks-1428

    5. Pmb

    6. Akos025392172

    7. Polymyxin B Sulfate, Bacillus Polymyxa

    8. M02428

    9. Polymyxin B Sulfate (1404-26-8 Free Base)

    10. 405p205

    2.3 Create Date
    2010-12-22
    3 Chemical and Physical Properties
    Molecular Weight 1301.6 g/mol
    Molecular Formula C56H100N16O17S
    Hydrogen Bond Donor Count20
    Hydrogen Bond Acceptor Count22
    Rotatable Bond Count29
    Exact Mass1300.71730696 g/mol
    Monoisotopic Mass1300.71730696 g/mol
    Topological Polar Surface Area574 Ų
    Heavy Atom Count90
    Formal Charge0
    Complexity2240
    Isotope Atom Count0
    Defined Atom Stereocenter Count12
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NamePolymyxin b sulfate
    Drug LabelPolymyxin B for Injection, USP is one of a group of basic polypeptide antibiotics derived from B polymyxa (B aerosporous). Polymyxin B sulfate is the sulfate salt of Polymyxins B1 and B2, which are produced by the growth of Bacillus polymyxa (Prazmow...
    Active IngredientPolymyxin b sulfate
    Dosage FormInjectable
    RouteInjection
    Strengtheq 500,000 u base/vial
    Market StatusPrescription
    CompanyX Gen Pharms; Xellia Pharms Aps; Fresenius Kabi Usa; Eurohlth Intl

    2 of 2  
    Drug NamePolymyxin b sulfate
    Drug LabelPolymyxin B for Injection, USP is one of a group of basic polypeptide antibiotics derived from B polymyxa (B aerosporous). Polymyxin B sulfate is the sulfate salt of Polymyxins B1 and B2, which are produced by the growth of Bacillus polymyxa (Prazmow...
    Active IngredientPolymyxin b sulfate
    Dosage FormInjectable
    RouteInjection
    Strengtheq 500,000 u base/vial
    Market StatusPrescription
    CompanyX Gen Pharms; Xellia Pharms Aps; Fresenius Kabi Usa; Eurohlth Intl

    API Reference Price

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SHANGHAI SDNF CN","customerAddress":"UNIT NO.24 STEEL MADE INDL.ESTATE"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1735929000,"product":"POLYMYXIN B SULFATE (LIC.NO. SW\/OD\/11\/2024\/000007836 DT.04.12.24)POLYMYXIN B SULFATE (LIC.NO. SW\/OD\/11\/2024\/000007836 DT.04.1","address":"304, SAMAAN-II, OPP. RELIANCE","city":"GARDEN SATELLITE, AHMEDABAD-GUJARAT","supplier":"KINGLAND TRADING CO LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"SWISS PARENTERALS LTD","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"3073","totalValueFC":"6172.4","currency":"USD","unitRateINR":"266121.8","date":"04-Jan-2025","totalValueINR":"532243.6","totalValueInUsd":"6172.4","indian_port":"Ahmedabad Air","hs_no":"29419090","bill_no":"7618339","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"ROOM 1001-1008, JIADE PLAZA, QINGCH UN ROAD 118, HANGZHOU, ZHEJIANG PRO VINCE, CHINA CHINA","customerAddress":"304, SAMAAN-II, OPP. RELIANCE"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1737138600,"product":"POLYMYXIN B SULFATE USP (QTY: 75BOU\/9.375KG) POLYMYXIN B SULFATE USP (QTY: 75BOU\/9.375KG)","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"CHEMEXCEL INTERNATIONAL ASIA LIMI","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"GUFIC BIOSCIENCES LTD","customerCountry":"INDIA","quantity":"9.38","actualQuantity":"9.375","unit":"KGS","unitRateFc":"3360","totalValueFC":"31818.1","currency":"USD","unitRateINR":"292656","date":"18-Jan-2025","totalValueINR":"2743650","totalValueInUsd":"31818.1","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"7863087","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"TEDRM 801-2 8\/F EASEY COMM BLDG 253 -261HENNESSY RD, WANCHAI, SDNF HONG KONG","customerAddress":"2NF FLOOR,BUILDING A,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1739298600,"product":"P0972-1MU POLYMYXIN B SULFATE MEETS USP TESTING S [4252MG] [FOR FURTHER SALE]","address":"PLOT.NO.12,BOMMASANDRA-JIGANI LINK","city":"BANGALORE","supplier":"UNDISCLOSED","supplierCountry":"GERMANY","foreign_port":"FRANKFURT AM MAIN, HE","customer":"SIGMA ALDRICH CHEMICALS PRIVATE LTD","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"9","unit":"GMS","unitRateFc":"11.2","totalValueFC":"102.7","currency":"INR","unitRateINR":"991.9","date":"12-Feb-2025","totalValueINR":"8927","totalValueInUsd":"102.7","indian_port":"Bangalore Air","hs_no":"29419090","bill_no":"8318552","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT AM MAIN, HE","supplierAddress":"N\/A","customerAddress":"PLOT.NO.12,BOMMASANDRA-JIGANI LINK"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1748802600,"product":"POLYMYXIN B SULFATE (A200-000) POLYMYXIN B SULFATE (A200-000)","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"BIOTIKA AS","supplierCountry":"SLOVAKIA","foreign_port":"BRATISLAVA","customer":"AMNEAL PHARMACEUTICALS PRIVATE LTD","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25.001","unit":"KGS","unitRateFc":"4403.1","totalValueFC":"110690.5","currency":"USD","unitRateINR":"380429.8","date":"02-Jun-2025","totalValueINR":"9511125.98","totalValueInUsd":"110690.5","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29419019","bill_no":"2412529","productDescription":"API","marketType":"REGULATED MARKET","country":"SLOVAKIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BRATISLAVA","supplierAddress":"SLOVENSKA LUPCA 566 976 13 SLOVENSKA LUPCA SDNF SK","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1751567400,"product":"POLYMYXIN B SULFATE POLYMYXIN B SULFATE","address":"NARBAVI NO3 LAKSHMANAN STREET,,T.N","city":"CHENNAI,TAMIL NADU","supplier":"M\/S.BIOTIKA A.S","supplierCountry":"SLOVAKIA","foreign_port":"BRATISLAVA","customer":"CAPLIN STERILES LTD","customerCountry":"INDIA","quantity":"0.62","actualQuantity":"0.624","unit":"KGS","unitRateFc":"5782","totalValueFC":"3613.6","currency":"EURO","unitRateINR":"498407.5","date":"04-Jul-2025","totalValueINR":"311006.25","totalValueInUsd":"3613.6","indian_port":"Madras Air","hs_no":"29419090","bill_no":"3053986","productDescription":"API","marketType":"REGULATED MARKET","country":"SLOVAKIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BRATISLAVA","supplierAddress":"SLOVENSKA LUPCA 566 976 13 SLOVENSKA LUPCA SLOVAK REPUBLIC SK","customerAddress":"NARBAVI NO3 LAKSHMANAN STREET,,T.N"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1753381800,"product":"POLYMYXIN B SULFATE USP (QTY: 60BOU\/7.5KG) POLYMYXIN B SULFATE USP (QTY: 60BOU\/7.5KG)","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"CHEMEXCEL INTERNATIONAL ASIA LIMI","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"GUFIC BIOSCIENCES LTD","customerCountry":"INDIA","quantity":"0.36","actualQuantity":"0.36","unit":"KGS","unitRateFc":"3080","totalValueFC":"1118.3","currency":"USD","unitRateINR":"267344","date":"25-Jul-2025","totalValueINR":"96243.84","totalValueInUsd":"1118.3","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"3490488","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"TEDRM 801-2 8\/F EASEY COMM BLDG 253 -261HENNESSY RD, WANCHAI, SDNF HONG KONG","customerAddress":"2NF FLOOR,BUILDING A,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1753381800,"product":"POLYMYXIN B SULFATE USP (QTY: 60BOU\/7.5KG) POLYMYXIN B SULFATE USP (QTY: 60BOU\/7.5KG)","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"CHEMEXCEL INTERNATIONAL ASIA LIMI","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"GUFIC BIOSCIENCES LTD","customerCountry":"INDIA","quantity":"1.23","actualQuantity":"1.225","unit":"KGS","unitRateFc":"3080","totalValueFC":"3805.2","currency":"USD","unitRateINR":"267344","date":"25-Jul-2025","totalValueINR":"327496.4","totalValueInUsd":"3805.2","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"3490488","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"TEDRM 801-2 8\/F EASEY COMM BLDG 253 -261HENNESSY RD, WANCHAI, SDNF HONG KONG","customerAddress":"2NF FLOOR,BUILDING A,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1753381800,"product":"POLYMYXIN B SULFATE USP (QTY: 60BOU\/7.5KG) POLYMYXIN B SULFATE USP (QTY: 60BOU\/7.5KG)","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"CHEMEXCEL INTERNATIONAL ASIA LIMI","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"GUFIC BIOSCIENCES LTD","customerCountry":"INDIA","quantity":"4.40","actualQuantity":"4.4","unit":"KGS","unitRateFc":"3080","totalValueFC":"13667.6","currency":"USD","unitRateINR":"267344","date":"25-Jul-2025","totalValueINR":"1176313.6","totalValueInUsd":"13667.6","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"3490488","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"TEDRM 801-2 8\/F EASEY COMM BLDG 253 -261HENNESSY RD, WANCHAI, SDNF HONG KONG","customerAddress":"2NF FLOOR,BUILDING A,"}]
    17-Feb-2022
    25-Jul-2025
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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG ...DOSAGE - OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG BASE/GM;10,000 UNITS/GM

    USFDA APPLICATION NUMBER - 50065

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    DOSAGE - OINTMENT;TOPICAL - 400 UNITS/GM;1%;E...DOSAGE - OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 50168

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    DOSAGE - CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/G...DOSAGE - CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/GM;10,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 50218

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    DOSAGE - OINTMENT;OPHTHALMIC - 400 UNITS/GM;E...DOSAGE - OINTMENT;OPHTHALMIC - 400 UNITS/GM;EQ 3.5MG BASE/GM;10,000 UNITS/GM

    USFDA APPLICATION NUMBER - 50417

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    DOSAGE - SOLUTION/DROPS;OPHTHALMIC - 10,000 U...DOSAGE - SOLUTION/DROPS;OPHTHALMIC - 10,000 UNITS/ML;EQ 1MG BASE/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 50567

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    Colombia.png
    Polymyxin B Sulfate (500,000 units/ Vial) Injections needed in Colombia [ENA11553]
    A company that deals in the distribution of hospital drugs and specialized medical devices is looking for suppliers of Polymyxin B Sulfate (500,000 units/ Vial) Injections for commercial purpose. The required quantity is 50,000 units/ annum. The suppliers must support this enquiry with USFDA.
    04 Oct 2021

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    04 Oct 2021

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    04 Oct 2021

    Brazil.png
    Polymyxin B (500,000 EQ) Injections needed in Brazil [ENA10613]
    A company that is leading the freedom of choice and the customized configuration of integrated solutions for the entire health and well-being chain is looking for suppliers of Polymyxin B (500,000 EQ) Injections for commercial purposes. The required quantity is 2,00,000 units/ week.
    11 Jun 2021

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    11 Jun 2021

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    11 Jun 2021

    Brazil.png
    Various Finished Dosage Formulations needed in Brazil [ENA10069]
    One of the Brazilian Ministries is looking for suppliers of Various Finished Dosage Formulations for commercial purposes. The required quantity is MOQ for each. 1. Etomidate (2 mg/ ml in 10 ml) Injections 2. Dextroketamine (50 mg/ ml in 10 ml) Injections 3. Propofol 1% (10 mg /ml in 50 ml) Injection Syringe 4. Propofol 1% (10 mg/ ml in 50 ml bottle) Ampoules 5. Midazolam (5 mg/ ml in 10 ml) Ampoules 6. Suxamethonium Chloride (100 mg) Vials 7. Rocuronium Bromide (10 mg/ ml in 5 ml) Injections Bottle 8. Cisatracurium (5 ml) Ampoules 9. Pancuronium Bromide (2 mg/ ml in 2 ml) Injections 10. Dexmedetomidine (100 mcg/ ml in 2 ml) injections 11. Magnesium Sulphate (10%) Injectable Solution 12. Fentanyl Citrate (7.85 mg in 10 ml) Injectable Solution Ampoules Bottle 13. Morphine (10 mg/ ml in 10 ml) Ampoules 14. Lidocaine (2% in 20 ml without Vase) Bottle 15. Norepinephrine (1mg/ ml in 4 ml) Injections 16. Epinephrine (1 mg/ ml in 1 ml) Ampoules 17. Azithromycin (500 mg) Injectable Solution 18. Ceftriaxone (1 g) Injections 19. Linezolid (2mg/ ml in 300 ml) Flexible Injection Bag 20. Meropenem (1 g) Injections 21. Polymyxin B Sulphate (500 IU) Powder for Injectable Solution 22. Tigecycline (50 mg) Injections 23. Vecuronium Bromide (4 mg) Powder for Injection 24. Atracurium Besylate (10 mg/ ml in 5 ml) Ampoule
    27 Mar 2021

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    27 Mar 2021

    Brazil.png
    Various Sterile Finished Formulations needed in Brazil [ENA06770]
    A company offers a wide variety of pharmaceutical-grade medicines including expectorants, mineral supplements, topical antifungal agents, nasal decongestants, antibiotics, and antidepressants is looking for suppliers of Various Finished Dose Formulations: 1. Teicoplanin 66.6 mg/ml + Sodium Chloride (200 mg/ 3ml) Sterile Powder for Injection 2. Teicoplanin 66.6 mg/ml + Sodium Hydroxide (200 mg/ 3ml) Sterile Powder for Injection 3. Teicoplanin 133.3 mg/ml + Sodium Chloride (400 mg/ 3ml) Sterile Powder for Injection 4. Teicoplanin 133.3 mg/ml + Sodium Hydroxide (400 mg/ 3ml) Sterile Powder for Injection 5. Ampicillin + Sulbactam (1000 + 500 mg) Sterile Powder for Injection 6. Ampicillin + Sulbactam (2000 + 1000 mg) Sterile Powder for Injection 7. Ceftazidime 1g + Sodium Carbonate Sterile Powder for Injection 8. Polymyxin B 500,000 UI Sterile Powder for Injection 9. Amoxicillin + Clavulanate (1000 + 200 mg) Sterile Powder for Injection 10. Cefazolin 1g Sterile Powder for Injection 11. Remifentanil 2 mg + Glycine Sterile Powder for Injection 12. Tigecycline 50 mg + Lactose Monohydrate + Hydrochloric Acid Sterile Powder for Injection 13. Parecoxib Sodium 40 mg + Sodium Phosphate Dibasic Heptahydrate + Phosphoric Acid Lyophilized Sterile Powder for Injection 14. Cefuroxime Sodium Sterile Powder for Injection 15. Suxamethonium Chloride Anhydrous Sterile Powder for Injection 16. Clarithromycin + Lactobionic Acid Sterile Powder for Injection 17. Amphotericin B (Liposomal) + Phosphatidylcholines + Soya Hydrogenated + Cholesterol + 1,2-Distearoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt + (±)-Alfa-Tocopherol + Sucrose + Sodium Succinate Dibasic Hexahydrate Sterile Powder for Injection 18. Tenoxicam (20 mg Formulation) + Sodium Phosphate Monobasic Monohydrate + Sodium Phosphate Dibasic + Sodium Phosphate + D-Mannitol Sterile Powder for Injection 19. Tenoxicam (40 mg Formulation) + Sodium Phosphate Monobasic Monohydrate + Sodium Phosphate Dibasic + Sodium Phosphate + D-Mannitol + Povidone Sterile Powder for Injection 20. Piperacillin 2g + Tazobactam 250 mg + Sodium Bicarbonate + Monohydrate Citric Acid Lyophilized Powder for Injection 21. Piperacillin 4g + Tazobactam 500 mg + Sodium Bicarbonate + Monohydrate Citric Acid Lyophilized Powder for Injection 22. Voriconazole 200 mg + Betadex Sulfobutyl Ether Sodium Sterile Powder for Injection 23. Omeprazole Sodium + D-Mannitol Sterile Powder for Injection 24. Pantoprazole Sodium + Ethylenediaminetetraacetic Acid Tetrasodium Salt Dihydrate + Sodium Hydroxide Sterile Powder for Injection 25. Ketoprofen 100 mg + Sodium Hydroxide + Glycine + Monohydrate Citric Acid Sterile Powder for Injection 26. Azithromycin Dihydrate + Sodium Hydroxide + Monohydrate Citric Acid Sterile Powder for Injection 27. Daptomycin 500 mg + Sodium Hydroxide Lyophilized Powder for Injection 28. Ketoprofen 50 mg/ml Injectable Solution 29. Morphine Sulfate Pentahydrate 0.2 mg/ml & 10 mg/ml Injectable Solution 30. Dexamethasone + Thiamine Hydrochloride + Pyridoxine Hydrochloride + Cyanocobalamin Injectable Solution 31. Metoprolol Tartrate Injectable Solution
    06 Mar 2020

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    06 Mar 2020

    China.png
    Polymyxin B Injection needed in China [ENA04292]
    A company provides contract-based research services for pharmaceutical, medical, bacteriological, and biological companies is looking for suppliers of Polymyxin B Injection formulation. Suppliers must also support CTD dossier for this enquiry.
    29 May 2019

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    29 May 2019

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    29 May 2019

    Canada.png
    Neomycin / Polymyxin B / Bacitracin ointments needed in Canada [ENA03491]
    A global supplier of high-quality raw materials, carrying a full line of pharmaceutical ingredients, nutraceuticals, natural herbal extracts, speciality & fine chemicals, as well as custom designed products for all industries worldwide is looking for suppliers of the following products: 1. Neomycin / Polymyxin B / Bacitracin ointment Package: 15 /30 g. | Quantity - 10,000 units 2. Neomycin sulfate ointment (3.5 - 5 mg/g) + analgesic ingredient (as suitable). | Quantity - 10,000 units
    21 Feb 2019

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    21 Feb 2019

    Market Place
    Enquiry// Various ophthalmic formulations (eye drops) needed in Algeria [ENA00703]
    A private Algerian group is looking for import and tech transfer of generic eye drops from Europe as per following business model: i) Three years of finished product import. ii) Tech transfer of the imported products after three years of import. The requested products are: 1. N-Acetylaspartylglutamic Acid 4.9 g/100ML 2. Carbomer Gel 2.5 mg 3. Dexamethasone/Neomycin/Polymyxin B 100 mg/350,000UI/60,0000UI 4. Rifamycin 1,000,000 UI/100ML 5. Indomethacin 0.1% 6. Carteolol 1% 7. Levocabastine 0.05% 8. Dexamethasone/Neomycin 100 mg/350,000 UI/100ML 9. Norfloxacin 0,3% ( 3 MG/ML) 10. Gatifloxacin 0.3% 11. Picloxydine Chlorhydrate 0.05% 12. Povidone 1.5% 13. Tropicamide 5% 14. Oxybuprocaine 0.40% 15. Phenylephrine 10%
    13 Feb 2018

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    13 Feb 2018

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    13 Feb 2018

    PharmaCompass
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    REF. STANDARDS & IMPURITIES

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    EDQM

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    01

    EDQM, Council of Europe

    Polymyxin B sulfate

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    Not Confirmed

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    EDQM, Council of Europe

    France
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    Polymyxin B sulfate

    CAS Number : 1405-20-5

    Quantity Per Vial : 25 mg

    Sale Unit : 1

    Order Code : P2400000

    Batch No : 6

    Price (€) : 79

    Storage : +5°C ± 3°C

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    XYZ Pharma

    Gabon
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    XYZ Pharma

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    Polymyxin B Sulfate (200 mg) (COLD SHIPMENT R...

    CAS Number :

    Quantity Per Vial : 200

    Sale Unit : mg

    Price : $245.00

    Details : Material Origin- Fermentation; USMCA- No; KOR...

    Monograph :

    Storage :

    Code/Batch No : Catalog #1547007 / R104F0

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    Looking for 1405-20-5 / Polymyxin B Sulfate API manufacturers, exporters & distributors?

    Polymyxin B Sulfate manufacturers, exporters & distributors 1

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    API | Excipient name

    Polymyxin B Sulfate

    Synonyms

    Polymyxin b, sulfate (salt), 1405-20-5, Polymixin b sulphate, Ks-1428, Pmb, Akos025392172

    Cas Number

    1405-20-5

    Polymyxin B Manufacturers

    A Polymyxin B manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Polymyxin B, including repackagers and relabelers. The FDA regulates Polymyxin B manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Polymyxin B API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Polymyxin B manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Polymyxin B Suppliers

    A Polymyxin B supplier is an individual or a company that provides Polymyxin B active pharmaceutical ingredient (API) or Polymyxin B finished formulations upon request. The Polymyxin B suppliers may include Polymyxin B API manufacturers, exporters, distributors and traders.

    click here to find a list of Polymyxin B suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Polymyxin B USDMF

    A Polymyxin B DMF (Drug Master File) is a document detailing the whole manufacturing process of Polymyxin B active pharmaceutical ingredient (API) in detail. Different forms of Polymyxin B DMFs exist exist since differing nations have different regulations, such as Polymyxin B USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Polymyxin B DMF submitted to regulatory agencies in the US is known as a USDMF. Polymyxin B USDMF includes data on Polymyxin B's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Polymyxin B USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Polymyxin B suppliers with USDMF on PharmaCompass.

    Polymyxin B JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Polymyxin B Drug Master File in Japan (Polymyxin B JDMF) empowers Polymyxin B API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Polymyxin B JDMF during the approval evaluation for pharmaceutical products. At the time of Polymyxin B JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Polymyxin B suppliers with JDMF on PharmaCompass.

    Polymyxin B KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Polymyxin B Drug Master File in Korea (Polymyxin B KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Polymyxin B. The MFDS reviews the Polymyxin B KDMF as part of the drug registration process and uses the information provided in the Polymyxin B KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Polymyxin B KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Polymyxin B API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Polymyxin B suppliers with KDMF on PharmaCompass.

    Polymyxin B CEP

    A Polymyxin B CEP of the European Pharmacopoeia monograph is often referred to as a Polymyxin B Certificate of Suitability (COS). The purpose of a Polymyxin B CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Polymyxin B EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Polymyxin B to their clients by showing that a Polymyxin B CEP has been issued for it. The manufacturer submits a Polymyxin B CEP (COS) as part of the market authorization procedure, and it takes on the role of a Polymyxin B CEP holder for the record. Additionally, the data presented in the Polymyxin B CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Polymyxin B DMF.

    A Polymyxin B CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Polymyxin B CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Polymyxin B suppliers with CEP (COS) on PharmaCompass.

    Polymyxin B WC

    A Polymyxin B written confirmation (Polymyxin B WC) is an official document issued by a regulatory agency to a Polymyxin B manufacturer, verifying that the manufacturing facility of a Polymyxin B active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Polymyxin B APIs or Polymyxin B finished pharmaceutical products to another nation, regulatory agencies frequently require a Polymyxin B WC (written confirmation) as part of the regulatory process.

    click here to find a list of Polymyxin B suppliers with Written Confirmation (WC) on PharmaCompass.

    Polymyxin B NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Polymyxin B as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Polymyxin B API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Polymyxin B as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Polymyxin B and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Polymyxin B NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Polymyxin B suppliers with NDC on PharmaCompass.

    Polymyxin B GMP

    Polymyxin B Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Polymyxin B GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Polymyxin B GMP manufacturer or Polymyxin B GMP API supplier for your needs.

    Polymyxin B CoA

    A Polymyxin B CoA (Certificate of Analysis) is a formal document that attests to Polymyxin B's compliance with Polymyxin B specifications and serves as a tool for batch-level quality control.

    Polymyxin B CoA mostly includes findings from lab analyses of a specific batch. For each Polymyxin B CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Polymyxin B may be tested according to a variety of international standards, such as European Pharmacopoeia (Polymyxin B EP), Polymyxin B JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Polymyxin B USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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