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    Chemistry

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    Also known as: 2398-96-1, Tinactin, Tonoftal, Tolnaphthate, Sporiline, Tinaderm
    Molecular Formula
    C19H17NOS
    Molecular Weight
    307.4  g/mol
    InChI Key
    FUSNMLFNXJSCDI-UHFFFAOYSA-N
    FDA UNII
    06KB629TKV
    Tolnaftate
    A synthetic antifungal agent.
    1 2D Structure

    Tolnaftate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate
    2.1.2 InChI
    InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3
    2.1.3 InChI Key
    FUSNMLFNXJSCDI-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2
    2.2 Other Identifiers
    2.2.1 UNII
    06KB629TKV
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Aftate

    2. Breezee

    3. Chinofungin

    4. Chlorisept

    5. Curatin

    6. Genaspor

    7. Micoisdin

    8. Np 27

    9. Np-27

    10. Np27

    11. Ony Clear

    12. Ony-clear

    13. Purder N, Tolnaftat

    14. Sporiline

    15. Tinactin

    16. Tinaderm

    17. Tinatox

    18. Tineafax

    19. Ting

    20. Tolnaftat Purder N

    21. Tonoftal

    22. Zeasorb

    2.3.2 Depositor-Supplied Synonyms

    1. 2398-96-1

    2. Tinactin

    3. Tonoftal

    4. Tolnaphthate

    5. Sporiline

    6. Tinaderm

    7. Tolsanil

    8. Aftate

    9. Chinofungin

    10. Dermoxin

    11. Focusan

    12. Tinavet

    13. Pitrex

    14. Naphthiomate T

    15. Phytoderm

    16. Timoped

    17. Tritin

    18. Hi-alazin

    19. Fungistop

    20. Tolnaftato

    21. Tolnaftatum

    22. Separin

    23. Sorgoa

    24. Sch 10144

    25. O-2-naphthyl M,n-dimethylthiocarbanilate

    26. Dungistop

    27. Tniaderm

    28. Naphthiomate-t

    29. Hi-alarzin

    30. 2-naphthyl N-methyl-n-(3-tolyl)thionocarbamate

    31. M,n-dimethylthiocarbanilic Acid O-2-naphthyl Ester

    32. O-naphthalen-2-yl N-methyl-n-(3-methylphenyl)carbamothioate

    33. Prestwick_472

    34. Dr. Scholl's Athlete's Foot Spray

    35. Methyl (3-methylphenyl)carbamothioic Acid O-2-naphthalenyl Ester

    36. Carbamothioic Acid, Methyl(3-methylphenyl)-, O-2-naphthalenyl Ester

    37. Carbanilic Acid, M,n-dimethylthio-, O-2-naphthyl Ester

    38. Carbanilic Acid, N,m-dimethylthio-, O-2-naphthyl Ester

    39. Nsc 233648

    40. Mls000028526

    41. N-methyl-n-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide

    42. O-naphthalen-2-yl N-methyl-n-(3-methylphenyl)thiocarbamate

    43. Nsc-233648

    44. Smr000058288

    45. 06kb629tkv

    46. Chebi:9620

    47. Tolnaftato [dcit]

    48. O-naphthalen-2-yl Methyl(m-tolyl)carbamothioate

    49. O-2-naphthyl Methyl(3-methylphenyl)carbamothioate

    50. Sch-10144

    51. Tolnaftatum [inn-latin]

    52. Ncgc00016610-01

    53. Tolnaftato [inn-spanish]

    54. Tinavet (veterinary)

    55. Genaspore Cream

    56. Tinactin Powder

    57. Cas-2398-96-1

    58. Tinactin Cream

    59. Pitrex Cream

    60. N-methyl-n-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide

    61. Ting Products

    62. Tinactin Solution

    63. Carbamothioic Acid, N-methyl-n-(3-methylphenyl)-, O-2-naphthalenyl Ester

    64. Dsstox_cid_22477

    65. Dsstox_rid_80034

    66. Zeasorb-af Powder

    67. Dsstox_gsid_42477

    68. Tinactin (tn)

    69. Separin (tn)

    70. Np-27 Solution

    71. Tinactin Plus Powder

    72. Ting Antifungal Cream

    73. Np-27 Powder

    74. Ting Antifungal Powder

    75. Np-27 Cream

    76. Tinactin Aerosol Liquid

    77. Tinactin Aerosol Powder

    78. Np-27 Spray Powder

    79. Tinactin Jock Itch Cream

    80. Aftate For Jock Itch Gel

    81. Tinactin Plus Aerosol Powder

    82. Ting Antifungal Spray Liquid

    83. Ting Antifungal Spray Powder

    84. Aftate For Athlete's Foot Gel

    85. Tolnafrate

    86. Tinactin Jock Itch Spray Powder

    87. Tinactin Jock Itch Aerosol Powder

    88. Sr-01000003084

    89. Aftate For Jock Itch Sprinkle Powder

    90. Einecs 219-266-6

    91. Brn 2752620

    92. Tolnoftate

    93. Unii-06kb629tkv

    94. Tolnaflate

    95. O-2-naphthyl N,n-dimethylthiocarbanilate

    96. Aftate For Jock Itch Aerosol Spray Powder

    97. Tinactin Antifungal Deodorant Powder Aerosol

    98. Methyl-(3-methylphenyl)carbamothioic Acid O-2-naphthyl Ester

    99. Tolnaftate-10kg

    100. Carbamothiolic Acid

    101. O-2-naphthyl Methyl(3-methylphenyl)thiocarbamate

    102. Mfcd00056611

    103. O-naphthalen-2-yl Methyl(3-methylphenyl)carbamothioate

    104. Tolnaftate [usan:usp:inn:ban:jan]

    105. Spectrum_000963

    106. N-dimethylthiocarbanilate

    107. Tolnaftate [mi]

    108. Tolnaftate [inn]

    109. Tolnaftate [jan]

    110. Opera_id_1698

    111. Prestwick0_000070

    112. Prestwick1_000070

    113. Prestwick2_000070

    114. Prestwick3_000070

    115. Spectrum2_000950

    116. Spectrum4_000360

    117. Spectrum5_001000

    118. Tolnaftate [inci]

    119. Tolnaftate [usan]

    120. Tolnaftate [vandf]

    121. Cid_5510

    122. Schembl3520

    123. Tolnaftate [mart.]

    124. Tolnaftate [usp-rs]

    125. Tolnaftate [who-dd]

    126. Bspbio_000259

    127. Kbiogr_000799

    128. Kbioss_001443

    129. Mls001146910

    130. O-(2-naphthyl) N-methyl-n-(m-tolyl)carbamothioate

    131. Chembl83668

    132. Divk1c_000334

    133. Spectrum1500583

    134. Spbio_000920

    135. Spbio_002180

    136. Bpbio1_000285

    137. Tolnaftate (jp17/usp/inn)

    138. Tolnaftate [green Book]

    139. Dtxsid3042477

    140. Bdbm39349

    141. Hms501a16

    142. Kbio1_000334

    143. Kbio2_001443

    144. Kbio2_004011

    145. Kbio2_006579

    146. Tolnaftate For System Suitability

    147. Zinc57522

    148. Tolnaftate [ep Monograph]

    149. Ninds_000334

    150. Hms1568m21

    151. Hms1921e21

    152. Hms2092o05

    153. Hms2095m21

    154. Hms2231o21

    155. Hms3373p10

    156. Hms3655d15

    157. Hms3712m21

    158. Pharmakon1600-01500583

    159. Tolnaftate [usp Monograph]

    160. Amy23403

    161. Bcp12071

    162. Hy-b0370

    163. Tox21_110521

    164. Tox21_301363

    165. N-methyl-(3-methylphenyl)-carbamothioic Acid, O-2-naphthalenyl Ester

    166. Nsc233648

    167. Nsc757355

    168. S2058

    169. Stl069548

    170. Akos005111014

    171. Tox21_110521_1

    172. Ac-5548

    173. Ccg-212827

    174. Db00525

    175. Ks-5115

    176. Nsc-757355

    177. Idi1_000334

    178. Ncgc00016610-02

    179. Ncgc00016610-03

    180. Ncgc00016610-04

    181. Ncgc00016610-05

    182. Ncgc00016610-07

    183. Ncgc00016610-08

    184. Ncgc00023506-03

    185. Ncgc00255761-01

    186. Carbamothioic Acid, O-2-naphthalenyl Ester

    187. Sbi-0051538.p002

    188. Db-046313

    189. Ab00052111

    190. Ft-0603605

    191. Sw196682-3

    192. T3059

    193. D00381

    194. H10435

    195. O-naphthalen-2-ylmethyl(m-tolyl)carbamothioate

    196. Ab00052111_17

    197. Ab00052111_18

    198. 398t961

    199. A817026

    200. O-(naphthalen-2-yl) Methyl(m-tolyl)carbamothioate

    201. Q415238

    202. Carbanilic Acid,m-dimethylthio-, O-2-naphthyl Ester

    203. Carbanilic Acid,n-dimethylthio-, O-2-naphthyl Ester

    204. Sr-01000003084-2

    205. Sr-01000003084-4

    206. W-107363

    207. Brd-k44273375-001-04-5

    208. Brd-k44273375-001-14-4

    209. Brd-k44273375-001-23-5

    210. O-(2-naphthyl) Methyl(3-methylphenyl)thiocarbamate #

    211. Methyl(3-methylphenyl)carbamothioic Acid O-2-naphthyl Ester

    212. N-methyl-n-(m-tolyl)thiocarbamic Acid O-(2-naphthyl) Ester

    213. Tolnaftate, European Pharmacopoeia (ep) Reference Standard

    214. Tolnaftate, United States Pharmacopeia (usp) Reference Standard

    215. Methyl-[3-methyl-2-(2-naphthyl)phenyl]carbamothioic S-acid;tolnaftate

    216. N-methyl-n-(3-methylphenyl)carbamothioic Acid O-(2-naphthalenyl) Ester

    217. Tolnaftate, Pharmaceutical Secondary Standard; Certified Reference Material

    218. Tinactin Pound>>tinaderm Pound>>aftate Pound>>np-27 Pound>>np 27 Pound>> Np27

    219. Tolnaftate For System Suitability, European Pharmacopoeia (ep) Reference Standard

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 307.4 g/mol
    Molecular Formula C19H17NOS
    XLogP35.5
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count3
    Exact Mass307.10308534 g/mol
    Monoisotopic Mass307.10308534 g/mol
    Topological Polar Surface Area44.6 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity386
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Tolnaftate topical is used to treat skin infections such as athlete's foot, jock itch, and ringworm infections. Tolnaftate is also used, along with other antifungals, to treat infections of the nails, scalp, palms, and soles of the feet. The powder and powder aerosol may be used to prevent athlete's foot.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Tolnaftate is a synthetic over-the-counter anti-fungal agent.

    5.2 MeSH Pharmacological Classification

    Antifungal Agents

    Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)

    5.3 FDA Pharmacological Classification
    5.3.1 Pharmacological Classes
    Azoles [CS]; Azole Antifungal [EPC]
    5.4 ATC Code

    D - Dermatologicals

    D01 - Antifungals for dermatological use

    D01A - Antifungals for topical use

    D01AE - Other antifungals for topical use

    D01AE18 - Tolnaftate

    5.5 Mechanism of Action

    Tolnaftate is a topical fungicide. Though its exact mechanism unknown, it is believed to prevent ergosterol biosynthesis by inhibiting squalene epoxidase. It has also been reported to distort the hyphae and to stunt mycelial growth in susceptible organisms.

    API Reference Price

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CHEMICALS","customerCountry":"CHINA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"42.5","totalValueFC":"7838.5","currency":"USD","unitRateINR":3394.7750000000001,"date":"03-Mar-2025","totalValueINR":"678955","totalValueInUsd":"7838.5","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"8674180","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"SWARUP BHAWAN 35-A,CIVIL LINES, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1741113000,"product":"TOLNAFTATE IP","address":"BG-533, SANJAY GANDHI TRANSPORT","city":"DELHI","supplier":"DRUG CENTRE DELHI PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"NATIONAL HEALTHCARE PVT LTD","customerCountry":"NEPAL","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"3175","totalValueFC":"183.3","currency":"INR","unitRateINR":3175,"date":"05-Mar-2025","totalValueINR":"15875","totalValueInUsd":"183.3","indian_port":"Raxaul","hs_no":"29309099","bill_no":"8726217","productDescription":"API","marketType":"","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"Raxaul","supplierAddress":"BG-533, SANJAY GANDHI TRANSPORT, DELHI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1741804200,"product":"DRUG & DRUG INTERMEDIATES: TOLNAFTATE B.P","address":"MAHENDRA INDL.ESTATE,III FLR.,PLOT","city":"MUMBAI ,MAHARASHTRA","supplier":"AARTI DRUGS LTD","supplierCountry":"INDIA","foreign_port":"HONG KONG","customer":"HONGKONG PHARMA","customerCountry":"HONG KONG","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"170","totalValueFC":"1635.3","currency":"USD","unitRateINR":14164.6,"date":"13-Mar-2025","totalValueINR":"141646","totalValueInUsd":"1635.3","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"8998347","productDescription":"Intermediate","marketType":"","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"MAHENDRA INDL.ESTATE,III FLR.,PLOT, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1741977000,"product":"DRUG & DRUG INTERMEDIATES: TOLNAFTATE B.P","address":"MAHENDRA INDL.ESTATE,III FLR.,PLOT","city":"MUMBAI ,MAHARASHTRA","supplier":"AARTI DRUGS LTD","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"EGYPT PHARMA","customerCountry":"EGYPT","quantity":"75.00","actualQuantity":"75","unit":"KGS","unitRateFc":"88","totalValueFC":"6560.6","currency":"USD","unitRateINR":7576.8000000000002,"date":"15-Mar-2025","totalValueINR":"568260","totalValueInUsd":"6560.6","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"9018547","productDescription":"Intermediate","marketType":"","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"MAHENDRA INDL.ESTATE,III FLR.,PLOT, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1743359400,"product":"DRUG & DRUG INTERMEDIATES: TOLNAFTATE U.S.P.","address":"MAHENDRA INDL.ESTATE,III FLR.,PLOT","city":"MUMBAI ,MAHARASHTRA","supplier":"AARTI DRUGS LTD","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"EGYPT PHARMA","customerCountry":"EGYPT","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"70","totalValueFC":"33688.2","currency":"USD","unitRateINR":5835.9799999999996,"date":"31-Mar-2025","totalValueINR":"2917990","totalValueInUsd":"33688.2","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"9562001","productDescription":"Intermediate","marketType":"","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"MAHENDRA INDL.ESTATE,III FLR.,PLOT, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745001000,"product":"DRUG & DRUG INTERMEDIATES: TOLNAFTATE U.S.P.","address":"MAHENDRA INDL.ESTATE,III FLR.,PLOT","city":"MUMBAI ,MAHARASHTRA","supplier":"AARTI DRUGS LTD","supplierCountry":"INDIA","foreign_port":"BANGKOK","customer":"THAILAND PHARMA","customerCountry":"THAILAND","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"95","totalValueFC":"2244.4","currency":"USD","unitRateINR":7685.0600000000004,"date":"19-Apr-2025","totalValueINR":"192126.5","totalValueInUsd":"2244.4","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"1097023","productDescription":"Intermediate","marketType":"","country":"THAILAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"MAHENDRA INDL.ESTATE,III FLR.,PLOT, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1746642600,"product":"TOLNAFTATE USP","address":"SWARUP BHAWAN 35-A,CIVIL LINES","city":"N\/A","supplier":"INDIA PESTICIDES LTD","supplierCountry":"INDIA","foreign_port":"BANGKOK","customer":"PHARMASERV COLTD","customerCountry":"THAILAND","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"51","totalValueFC":"1142.8","currency":"USD","unitRateINR":3894.75,"date":"08-May-2025","totalValueINR":"97368.75","totalValueInUsd":"1142.8","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"1621114","productDescription":"API","marketType":"","country":"THAILAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"SWARUP BHAWAN 35-A,CIVIL LINES, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1746815400,"product":"DRUG & DRUG INTERMEDIATES: TOLNAFTATE B.P","address":"MAHENDRA INDL.ESTATE,III FLR.,PLOT","city":"MUMBAI ,MAHARASHTRA","supplier":"AARTI DRUGS LTD","supplierCountry":"INDIA","foreign_port":"HONG KONG","customer":"HONGKONG PHARMA","customerCountry":"HONG KONG","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"145","totalValueFC":"661.1","currency":"USD","unitRateINR":11264.450000000001,"date":"10-May-2025","totalValueINR":"56322.25","totalValueInUsd":"661.1","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"1696320","productDescription":"Intermediate","marketType":"","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"MAHENDRA INDL.ESTATE,III FLR.,PLOT, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1747247400,"product":"TOLNAFTATE USP 2024 (BATCH NO : TLF\/1902\/FPO25\/001, MFG MONTH : APRIL 2025 RETEST MONTH : MARCH 2028)","address":"10-3-3, ASHOK NIKETAN, HOUSE,NUMBE","city":"SECUNDERABAD,TELANGANA","supplier":"HERMES CHEMICAL CO","supplierCountry":"INDIA","foreign_port":"SAN FRANCISCO, CA","customer":"COLUMBIA COSMETICS INC","customerCountry":"UNITED STATES","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"700","totalValueFC":"2558","currency":"USD","unitRateINR":54485,"date":"15-May-2025","totalValueINR":"217940","totalValueInUsd":"2558","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"1821592","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"10-3-3, ASHOK NIKETAN, HOUSE,NUMBE, SECUNDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1747247400,"product":"TOLNAFTATE USP 2024 BATCH NO: TLF\/1902\/FP025\/001","address":"10-3-3, ASHOK NIKETAN, HOUSE,NUMBE","city":"SECUNDERABAD,TELANGANA","supplier":"HERMES CHEMICAL CO","supplierCountry":"INDIA","foreign_port":"SAN FRANCISCO, CA","customer":"COLUMBIA COSMETICS INC","customerCountry":"UNITED STATES","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"300","totalValueFC":"7381.1","currency":"USD","unitRateINR":25155,"date":"15-May-2025","totalValueINR":"628875","totalValueInUsd":"7381.1","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"1832364","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"10-3-3, ASHOK NIKETAN, HOUSE,NUMBE, SECUNDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1749061800,"product":"DRUG & DRUG INTERMEDIATES: TOLNAFTATE U.S.P.","address":"MAHENDRA INDL.ESTATE,III FLR.,PLOT","city":"MUMBAI ,MAHARASHTRA","supplier":"AARTI DRUGS LTD","supplierCountry":"INDIA","foreign_port":"BANGKOK","customer":"THAILAND PHARMA","customerCountry":"THAILAND","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"95","totalValueFC":"4504","currency":"USD","unitRateINR":7740.1199999999999,"date":"05-Jun-2025","totalValueINR":"387006","totalValueInUsd":"4504","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"2469801","productDescription":"Intermediate","marketType":"","country":"THAILAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"MAHENDRA INDL.ESTATE,III FLR.,PLOT, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1749148200,"product":"DRUG & DRUG INTERMEDIATES: TOLNAFTATE U.S.P.","address":"MAHENDRA INDL.ESTATE,III FLR.,PLOT","city":"MUMBAI ,MAHARASHTRA","supplier":"AARTI DRUGS LTD","supplierCountry":"INDIA","foreign_port":"GUARULHOS","customer":"RBZ MARKETING","customerCountry":"BRAZIL","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"123","totalValueFC":"18262","currency":"USD","unitRateINR":10461.15,"date":"06-Jun-2025","totalValueINR":"1569172.5","totalValueInUsd":"18262","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"2483423","productDescription":"Intermediate","marketType":"","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"MAHENDRA INDL.ESTATE,III FLR.,PLOT, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1750962600,"product":"TOLNAFTATE USP","address":"SWARUP BHAWAN 35-A,CIVIL LINES","city":"N\/A","supplier":"INDIA PESTICIDES LTD","supplierCountry":"INDIA","foreign_port":"BANGKOK","customer":"PHARMASERV CO LTD","customerCountry":"THAILAND","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"51","totalValueFC":"2378.8","currency":"USD","unitRateINR":4088.0570000000002,"date":"27-Jun-2025","totalValueINR":"204402.85","totalValueInUsd":"2378.8","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"3081018","productDescription":"API","marketType":"","country":"THAILAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"SWARUP BHAWAN 35-A,CIVIL LINES, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1750962600,"product":"TOLNAFTATE USP","address":"SWARUP BHAWAN 35-A,CIVIL LINES","city":"N\/A","supplier":"INDIA PESTICIDES LTD","supplierCountry":"INDIA","foreign_port":"BANGKOK","customer":"PHARMASERV CO LTD","customerCountry":"THAILAND","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"51","totalValueFC":"2378.8","currency":"USD","unitRateINR":4088.0570000000002,"date":"27-Jun-2025","totalValueINR":"204402.85","totalValueInUsd":"2378.8","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"3091168","productDescription":"API","marketType":"","country":"THAILAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"SWARUP BHAWAN 35-A,CIVIL LINES, N\/A","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1752517800,"product":"PHARMACEUTICAL RAW MATERIAL-BULK DRUG FOR USE IN PHARMACEUTICAL INDUSTRIES TOLNAFTATE USP","address":"708, TIMES SQUARE ARCADE,","city":"AHMEDABAD","supplier":"SKJ HEALTHCARE PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"BAGDAD, METROPOLITAN","customer":"UNDISCLOSED","customerCountry":"IRAQ","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"48.1","totalValueFC":"871.4","currency":"USD","unitRateINR":3000.0644000000002,"date":"15-Jul-2025","totalValueINR":"75001.61","totalValueInUsd":"871.4","indian_port":"Ahmedabad Air","hs_no":"29309099","bill_no":"3585078","productDescription":"API","marketType":"","country":"IRAQ","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad Air","supplierAddress":"708, TIMES SQUARE ARCADE,, AHMEDABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1752604200,"product":"TOLNAFTATE USP CAS NO. :- 2398-96-1","address":"107\/108, ANJANI COMPLEX, P NO. 316","city":"ROAD., CHAKALA, ANDHERI (E) MUMBAI","supplier":"ZEN CHEMICALS PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"NEW YORK","customer":"UNDISCLOSED","customerCountry":"UNITED STATES","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"80","totalValueFC":"15274.9","currency":"USD","unitRateINR":6573.2550000000001,"date":"16-Jul-2025","totalValueINR":"1314651","totalValueInUsd":"15274.9","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"3596656","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"107\/108, ANJANI COMPLEX, P NO. 316, ROAD., CHAKALA, ANDHERI (E) MUMBAI","customerAddress":""}]
    08-Jan-2022
    16-Jul-2025
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

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    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    Canada

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    01

    BAYER INC

    Germany
    ACS Fall 2025
    Not Confirmed
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    BAYER INC

    Germany
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    ACS Fall 2025
    Not Confirmed
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    Regulatory Info :

    Registration Country : Canada

    TOLNAFTATE

    Brand Name : TINACTIN

    Dosage Form : CREAM

    Dosage Strength : 1%/W/W

    Packaging : 15/30GM

    Approval Date :

    Application Number : 576034

    Regulatory Info :

    Registration Country : Canada

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    02

    BAYER INC

    Germany
    ACS Fall 2025
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    BAYER INC

    Germany
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    ACS Fall 2025
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    Registration Country : Canada

    TOLNAFTATE

    Brand Name : TINACTIN POWDER

    Dosage Form : POWDER

    Dosage Strength : 1%/W/W

    Packaging : 100G

    Approval Date :

    Application Number : 576042

    Regulatory Info :

    Registration Country : Canada

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    03

    BAYER INC

    Germany
    ACS Fall 2025
    Not Confirmed
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    BAYER INC

    Germany
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    ACS Fall 2025
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    Registration Country : Canada

    TOLNAFTATE

    Brand Name : TINACTIN AEROSOL POWDER

    Dosage Form : AEROSOL

    Dosage Strength : 1%/W/W

    Packaging : 100GM

    Approval Date :

    Application Number : 576050

    Regulatory Info :

    Registration Country : Canada

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    04

    BAYER INC

    Germany
    ACS Fall 2025
    Not Confirmed
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    BAYER INC

    Germany
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    ACS Fall 2025
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    Registration Country : Canada

    TOLNAFTATE

    Brand Name : TINACTIN CHILL DEODORANT POWDER SPRAY

    Dosage Form : POWDER

    Dosage Strength : 1%/W/W

    Packaging : 100G

    Approval Date :

    Application Number : 2319276

    Regulatory Info :

    Registration Country : Canada

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    05

    BLISTEX CORPORATION

    Canada
    ACS Fall 2025
    Not Confirmed
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    BLISTEX CORPORATION

    Canada
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    ACS Fall 2025
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    Registration Country : Canada

    TOLNAFTATE

    Brand Name : ODOR-EATERS

    Dosage Form : AEROSOL

    Dosage Strength : 1%/W/W

    Packaging : 113G

    Approval Date :

    Application Number : 2244777

    Regulatory Info :

    Registration Country : Canada

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    06

    DOMINION VETERINARY LABORATORIES LTD.

    Canada
    ACS Fall 2025
    Not Confirmed
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    DOMINION VETERINARY LABORATORIES LTD.

    Canada
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    Registration Country : Canada

    TOLNAFTATE

    Brand Name : TOLNOXEQUINE THRUSH TREATMENT CREAM 1%

    Dosage Form : CREAM

    Dosage Strength : 1%/%

    Packaging : 75G

    Approval Date :

    Application Number : 2200791

    Regulatory Info :

    Registration Country : Canada

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    07

    LACORIUM HEALTH INTERNATIONAL PTY LTD.

    Australia
    ACS Fall 2025
    Not Confirmed
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    LACORIUM HEALTH INTERNATIONAL PTY LTD.

    Australia
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    ACS Fall 2025
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    Registration Country : Canada

    TOLNAFTATE

    Brand Name : FLEXITOL MEDICATED ANTI-FUNGAL CREAM

    Dosage Form : CREAM

    Dosage Strength : 1%

    Packaging : 56G/112G

    Approval Date :

    Application Number : 2295873

    Regulatory Info :

    Registration Country : Canada

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    08

    SCHOLL'S WELLNESS COMPANY

    U.S.A
    ACS Fall 2025
    Not Confirmed
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    SCHOLL'S WELLNESS COMPANY

    U.S.A
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    ACS Fall 2025
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    Registration Country : Canada

    TOLNAFTATE

    Brand Name : DR. SCHOLL'S ATHLETE'S FOOT SPRAY POWDER

    Dosage Form : POWDER

    Dosage Strength : 1%/W/W

    Packaging :

    Approval Date :

    Application Number : 1919245

    Regulatory Info :

    Registration Country : Canada

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    09

    TARO PHARMACEUTICALS INC

    U.S.A
    ACS Fall 2025
    Not Confirmed
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    TARO PHARMACEUTICALS INC

    U.S.A
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    ACS Fall 2025
    Not Confirmed
    • fda
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    TOLNAFTATE

    Brand Name : TOLNAFTATE CREAM USP, 1%

    Dosage Form : CREAM

    Dosage Strength : 1%

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    Approval Date :

    Application Number : 2226707

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    Registration Country : Canada

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    NSC PHARMA GMBH & CO.KG

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    TOLNAFTATE

    Brand Name : FOOT CARE FOAM

    Dosage Form : AEROSOL, FOAM

    Dosage Strength : 1%/W/W

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    Application Number : 2431718

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    Bayer Australia Ltd

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    Registration Country : Australia

    Tolnaftate

    Brand Name : Tinaderm

    Dosage Form : spray

    Dosage Strength : 0.07%

    Packaging : 1

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    Registration Country : Australia

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    Phyto OTC Health (Pty) Ltd

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    Regulatory Info : Originator

    Registration Country : South Africa

    Tolnaftate

    Brand Name : Quadriderm

    Dosage Form : CRE

    Dosage Strength : 10mg/g

    Packaging : 15X1mg/g

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    Regulatory Info : Originator

    Registration Country : South Africa

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    Tolnaftate (150 kg/ annum) API needed in United Kingdom [ENA21729]
    A company that focuses on compounding and distribution of various finished formulations is looking for suppliers of Tolnaftate (150 kg/ annum) API for commercial purposes. The suppliers must support this enquiry with CEP & CoA.
    14 Jan 2025

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    14 Jan 2025

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    Tolnaftate (25 kg) API needed in India [ENA21217]
    A company that focuses on manufacturing of various finished formulations is looking for suppliers of IP/ BP/ USP Grade Tolnaftate (25 kg) API for commercial purposes. The suppliers must support this enquiry with CoA.
    25 Nov 2024

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    25 Nov 2024

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    25 Nov 2024

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    Tolnaftate API needed in India [ENA19674]
    A company that focuses on the development and manufacturing of tablets, capsules, dry powder syrups/ suspensions, ointments, creams, gels and injectables is looking for suppliers Tolnaftate API for development purposes. The suppliers must support this enquiry with GMP & CoA.
    10 Jun 2024

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    10 Jun 2024

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    USP Grade Tolnaftate (750 kg/ annum) API needed in the United States [ENA17098]
    A CMO that focuses on injectables, suppositories, liquids and medical devices is looking for suppliers of USP Grade Tolnaftate (750 kg/ annum) API for commercial purposes. The suppliers must support this enquiry with USDMF (preferred) & CoA.
    15 May 2023

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    15 May 2023

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    Various APIs needed in U.A.E [ENA15986]
    A company having 25 years of experience that focuses on health and hygiene products is looking for suppliers of Various APIs for commercial purposes. The suppliers must support this enquiry with CoA. 1. Tolnaftate API 2. Racemic Camphor API
    03 Jan 2023

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    03 Jan 2023

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    USP Grade Tolnaftate (19 MT) API needed in the United States [ENA14719]
    A company that deals in various pharmaceutical products is looking for suppliers of USP Grade Tolnaftate (19 MT) API for commercial purpose. The suppliers must support this enquiry with CoA.
    18 Aug 2022

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    18 Aug 2022

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    Tolnaftate (MOQ) API needed in Colombia [ENA11286]
    A company that deals in the development, manufacturing and packaging of pharmaceutical, personal care and veterinary products in aerosol, creams, gels, ointments and liquid forms is looking for suppliers of Tolnaftate (MOQ) API for development purpose.
    03 Sep 2021

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    03 Sep 2021

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    Various APIs needed in India [ENA11083]
    A company that deals in the manufacturing of pharmaceutical formulations is looking for suppliers of Various APIs for development purpose. The suppliers must support this enquiry with CoA. 1. BP/USP Grade Tolnaftate (5 kg) API 2. Sterile Ceftazidime (2 g) and Avibactam (0.5 g) API as combination or separate.
    10 Aug 2021

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    10 Aug 2021

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    Pharma Grade Tolnaftate (50 kg) API needed in Germany [ENA11049]
    A CDMO that specialized in medicinal products such as aerosols, semi-solids, liquids and medical devices is looking for suppliers of Pharma Grade Tolnaftate (50 kg) API for commercial purpose. The suppliers must support this enquiry with GMP.
    06 Aug 2021

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    06 Aug 2021

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    Various APIs needed in India [ENA10005]
    Anuspa Heritage Products, a company that deals in cosmetic products is looking for suppliers of Various APIs. Interested suppliers can contact them via their email: bdo@anuspaheritage.com. 1. USP Grade Betamethasone Dipropionate API 2. BP Grade Gentamicin Sulfate API 3. USP Grade Tolnaftate API 4. Iodochlorhydroxyquin API
    20 Mar 2021

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    20 Mar 2021

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    ABOUT THIS PAGE

    Looking for 2398-96-1 / Tolnaftate API manufacturers, exporters & distributors?

    Tolnaftate manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Tolnaftate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Tolnaftate manufacturer or Tolnaftate supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tolnaftate manufacturer or Tolnaftate supplier.

    PharmaCompass also assists you with knowing the Tolnaftate API Price utilized in the formulation of products. Tolnaftate API Price is not always fixed or binding as the Tolnaftate Price is obtained through a variety of data sources. The Tolnaftate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Tolnaftate

    Synonyms

    2398-96-1, Tinactin, Tonoftal, Tolnaphthate, Sporiline, Tinaderm

    Cas Number

    2398-96-1

    Unique Ingredient Identifier (UNII)

    06KB629TKV

    About Tolnaftate

    A synthetic antifungal agent.

    KS-5115 Manufacturers

    A KS-5115 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of KS-5115, including repackagers and relabelers. The FDA regulates KS-5115 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. KS-5115 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of KS-5115 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    KS-5115 Suppliers

    A KS-5115 supplier is an individual or a company that provides KS-5115 active pharmaceutical ingredient (API) or KS-5115 finished formulations upon request. The KS-5115 suppliers may include KS-5115 API manufacturers, exporters, distributors and traders.

    click here to find a list of KS-5115 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    KS-5115 USDMF

    A KS-5115 DMF (Drug Master File) is a document detailing the whole manufacturing process of KS-5115 active pharmaceutical ingredient (API) in detail. Different forms of KS-5115 DMFs exist exist since differing nations have different regulations, such as KS-5115 USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A KS-5115 DMF submitted to regulatory agencies in the US is known as a USDMF. KS-5115 USDMF includes data on KS-5115's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The KS-5115 USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of KS-5115 suppliers with USDMF on PharmaCompass.

    KS-5115 JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The KS-5115 Drug Master File in Japan (KS-5115 JDMF) empowers KS-5115 API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the KS-5115 JDMF during the approval evaluation for pharmaceutical products. At the time of KS-5115 JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of KS-5115 suppliers with JDMF on PharmaCompass.

    KS-5115 CEP

    A KS-5115 CEP of the European Pharmacopoeia monograph is often referred to as a KS-5115 Certificate of Suitability (COS). The purpose of a KS-5115 CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of KS-5115 EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of KS-5115 to their clients by showing that a KS-5115 CEP has been issued for it. The manufacturer submits a KS-5115 CEP (COS) as part of the market authorization procedure, and it takes on the role of a KS-5115 CEP holder for the record. Additionally, the data presented in the KS-5115 CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the KS-5115 DMF.

    A KS-5115 CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. KS-5115 CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of KS-5115 suppliers with CEP (COS) on PharmaCompass.

    KS-5115 WC

    A KS-5115 written confirmation (KS-5115 WC) is an official document issued by a regulatory agency to a KS-5115 manufacturer, verifying that the manufacturing facility of a KS-5115 active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting KS-5115 APIs or KS-5115 finished pharmaceutical products to another nation, regulatory agencies frequently require a KS-5115 WC (written confirmation) as part of the regulatory process.

    click here to find a list of KS-5115 suppliers with Written Confirmation (WC) on PharmaCompass.

    KS-5115 NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing KS-5115 as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for KS-5115 API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture KS-5115 as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain KS-5115 and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a KS-5115 NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of KS-5115 suppliers with NDC on PharmaCompass.

    KS-5115 GMP

    KS-5115 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of KS-5115 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right KS-5115 GMP manufacturer or KS-5115 GMP API supplier for your needs.

    KS-5115 CoA

    A KS-5115 CoA (Certificate of Analysis) is a formal document that attests to KS-5115's compliance with KS-5115 specifications and serves as a tool for batch-level quality control.

    KS-5115 CoA mostly includes findings from lab analyses of a specific batch. For each KS-5115 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    KS-5115 may be tested according to a variety of international standards, such as European Pharmacopoeia (KS-5115 EP), KS-5115 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (KS-5115 USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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