menu
    • menu

    Find Isopropyl Alcohol manufacturers, exporters & distributors on PharmaCompass

    NEW Prospects: 3
    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    Virtual Booth

    Contact Supplier

    AbbVie CDMO has been working with global companies to develop, manufacture & scale biopharmaceutical products.

    Virtual Booth

    Contact Supplier

    Lupin Manufacturing Solutions – delivering high-quality APIs & end-to-end CDMO services for faster, cost-effective drug development.

    Virtual Booth

    Contact Supplier

    Minakem delivers API, HPAPI, steroids & CDMO services for generics with FDA/GMP certification, regulatory know-how & proven success.

    Virtual Booth

    Contact Supplier

    LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

    Virtual Booth

    Contact Supplier

    pharmacompass-2-m-2026-03-23

    Virtual Booth

    Contact Supplier

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    FINISHED DOSAGE FORMULATIONS

    DRUG PRODUCT COMPOSITIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    MARKET PLACE

    PATENTS & EXCLUSIVITIES

    REF. STANDARDS & IMPURITIES

    PharmaCompass

    Synopsis

    Related ProductsRelated Products

    Synopsis

    ACTIVE PHARMA INGREDIENTS

    6

    API Suppliers

    1

    USDMF

    1

    CEP/COS

    0

    JDMF

    0

    EU WC

    2

    KDMF

    0

    NDC API

    0

    VMF

    2

    Listed Suppliers

    0INTERMEDIATES

    REF. STANDARDS OR IMPURITIES

    1

    EDQM

    0

    USP

    0

    JP

    6

    Others

    FINISHED DOSAGE FORMULATIONS

    114

    FDF Dossiers

    18

    FDA Orange Book

    41

    Europe

    48

    Canada

    0

    Australia

    0

    South Africa

    7

    Listed Dossiers

    3PROSPECTS

    7DRUGS IN DEVELOPMENT

    FDF DossiersDRUG PRODUCT COMPOSITIONS

    73RELATED EXCIPIENT COMPANIES

    116EXCIPIENTS BY APPLICATIONS

    PATENTS & EXCLUSIVITIES

    8

    US Patents

    1

    US Exclusivities

    0

    Health Canada Patents

    GLOBAL SALES INFORMATION

    US Medicaid

    NA

    Annual Reports

    NA

    Regulatory FDF Prices

    NA

    MARKET PLACE

    6

    API

    0

    FDF

    DIGITAL CONTENT

    3

    Data Compilation #PharmaFlow

    0

    Stock Recap #PipelineProspector

    0

    Weekly News Recap #Phispers

    14

    News #PharmaBuzz

    Chemistry

    Click the arrow to open the dropdown
    read-moreClick the button for full data set
    read-moreClick the button for full data set
    Also known as: Isopropanol, 2-propanol, Propan-2-ol, 67-63-0, 2-hydroxypropane, Alkolave
    Molecular Formula
    C3H8O
    Molecular Weight
    60.10  g/mol
    InChI Key
    KFZMGEQAYNKOFK-UHFFFAOYSA-N
    FDA UNII
    ND2M416302
    Isopropyl Alcohol
    An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
    1 2D Structure

    Isopropyl Alcohol

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    propan-2-ol
    2.1.2 InChI
    InChI=1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
    2.1.3 InChI Key
    KFZMGEQAYNKOFK-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)O
    2.2 Other Identifiers
    2.2.1 UNII
    ND2M416302
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2 Propanol

    2. 2-propanol

    3. Alcohol, Isopropyl

    4. Alcohol, Rubbing

    5. Isopropanol

    6. Rubbing Alcohol

    2.3.2 Depositor-Supplied Synonyms

    1. Isopropanol

    2. 2-propanol

    3. Propan-2-ol

    4. 67-63-0

    5. 2-hydroxypropane

    6. Alkolave

    7. Avantine

    8. Hartosol

    9. Dimethylcarbinol

    10. Sec-propyl Alcohol

    11. I-propanol

    12. Petrohol

    13. Takineocol

    14. Alcojel

    15. Avantin

    16. 1-methylethanol

    17. 2-propyl Alcohol

    18. Alcolo

    19. Isohol

    20. Lavacol

    21. Lutosol

    22. Propol

    23. Alcosolve 2

    24. 1-methylethyl Alcohol

    25. Imsol A

    26. Arquad Dmcb

    27. Alcosolve

    28. Spectrar

    29. I-propylalkohol

    30. N-propan-2-ol

    31. Combi-schutz

    32. I-propyl Alcohol

    33. Isopropyl Alcohol, Rubbing

    34. Iso-propanol

    35. Iso-propylalkohol

    36. Alcool Isopropilico

    37. Visco 1152

    38. Alcool Isopropylique

    39. Sterisol Hand Disinfectant

    40. I-propanol [german]

    41. Sec-propanol

    42. Fema No. 2929

    43. I-propylalkohol [german]

    44. Iso-propyl Alcohol

    45. Iso-propylalkohol [german]

    46. Alcool Isopropilico [italian]

    47. Alcool Isopropylique [french]

    48. Iso-propylalcohol

    49. Alcohol,isopropyl

    50. Propanol-2

    51. Isopropyl Alcohol [usp]

    52. Mfcd00011674

    53. Nsc-135801

    54. Chebi:17824

    55. Nd2m416302

    56. 2-propanol, Anhydrous

    57. Ncgc00090917-01

    58. Rubbing Alcohol

    59. Dsstox_cid_762

    60. Isopropyl Alcohol (usp)

    61. Iproh

    62. Dsstox_rid_75777

    63. Dsstox_gsid_20762

    64. 2-propanol, Usp, 99.0%

    65. Caswell No. 507

    66. Isopropylalcohol

    67. Isopropyl Alcohol(2-d)

    68. Fema Number 2929

    69. 2-propanol, Acs Reagent, >=99.5%

    70. Cas-67-63-0

    71. Alcohol, Isopropyl

    72. Ccris 2308

    73. Hsdb 116

    74. Einecs 200-661-7

    75. Un1219

    76. Isopropyl Alcohol(1,1,1,3,3,3-d6)

    77. Nsc 135801

    78. Brn 0635639

    79. Isopropyl Alcohol(1,1,1,2,3,3,3-d7)

    80. Isoproylalcohol

    81. Virahol

    82. I-propylalcohol

    83. Lavaco

    84. Isopropylalkohol

    85. 2propanol

    86. 2-propylalcohol

    87. Isopropy Alcohol

    88. Isoproyl Alcohol

    89. Ai3-01636

    90. 2-propanolum

    91. Isopropyl-alcohol

    92. Propane-2ol

    93. Propan-2ol

    94. Unii-nd2m416302

    95. 2-propano

    96. Isopropryl Alcohol

    97. Propane-2-ol

    98. 2 -propanol

    99. 2- Propanol

    100. Propan 2-ol

    101. Iso-proh

    102. Isopropyl Alcohol

    103. I-proh

    104. (propan-2-ol)

    105. Isopro (tn)

    106. Recovered Isopropanol

    107. Tissue Dry Dehydrant

    108. Zuragard

    109. Isopropyl Alcohol C+

    110. Hibistat (salt/mix)

    111. I-pr-oh

    112. Propane, 2-hydroxy-

    113. 2-propanol, Ph Eur

    114. Iso-c3h7oh

    115. Isopropanol (jp17)

    116. Isopropanol (recovered)

    117. Isopropanol Acs Reagent

    118. 2-propanol, Gc Grade

    119. 2-propanol, For Hplc

    120. Isopropanol [jan]

    121. Isopropyl Alcohol - Gmp

    122. 2-propanol, Acs Reagent

    123. 2-propanol, Hplc Grade

    124. Chembl582

    125. Isopropyl Alcohol Hplc/uv

    126. 2-propanol, 99.5%

    127. Ec 200-661-7

    128. Ips 1

    129. Isopropanol, 70% In Water

    130. Isopropanol, 70% In H2o

    131. Isopropanol [who-dd]

    132. 4-01-00-01461 (beilstein Handbook Reference)

    133. Isopropyl Alcohol (manufacture Strong-acid Process)

    134. 2-propanol [usp-rs]

    135. 2-propanol [who-ip]

    136. Isopropanol, Isopropyl Alcohol

    137. Isopropyl Alcohol [ii]

    138. Isopropyl Alcohol [mi]

    139. Isopropanol, 99.5% Anhydrous

    140. Wln: Qy1&1

    141. 2-propanol, Analytical Standard

    142. Isopropanol Or Isopropyl Alcohol

    143. Isopropyl Alcohol [fcc]

    144. 2-propanol, Lr, >=99%

    145. Dtxsid7020762

    146. Isopropyl Alcohol [fhfi]

    147. Isopropyl Alcohol [hsdb]

    148. Isopropyl Alcohol [iarc]

    149. Isopropyl Alcohol [inci]

    150. Bdbm36154

    151. Alcohol,isopropyl [vandf]

    152. Isopropyl Alcohol (manufacturing-strong Acid Process Only)

    153. Isopropyl Alcohol [vandf]

    154. 2-propanol, Anhydrous, 99.5%

    155. Isopropyl Alcohol [mart.]

    156. Zinc901159

    157. 2-propanol, Ar, >=99.5%

    158. Amy11029

    159. Str00089

    160. 2-propanol, 99.9%, Pra Grade

    161. 2-propanol, For Hplc, 99.5%

    162. 2-propanol, For Hplc, 99.9%

    163. 2-propanol, Technical Grade, 95%

    164. Isopropyl Alcohol Reagent Grade Acs

    165. Tox21_111039

    166. Tox21_202475

    167. 2-propanol, 99.5%, Hplc Grade

    168. 2-propanol, Spectrophotometric Grade

    169. 2-propanolum [who-ip Latin]

    170. Nsc135801

    171. 2-propanol, Histological Grade, 99%

    172. Akos000121012

    173. 2-propanol, For Hplc, >=99.8%

    174. Db02325

    175. Isopropyl Alcohol (isopropanol)

    176. Isopropyl Alcohol [orange Book]

    177. Un 1219

    178. Isopropyl Alcohol [ep Monograph]

    179. 2-propanol 1000 Microg/ml In Methanol

    180. Acetone Impurity B [ep Impurity]

    181. Isopropyl Alcohol [usp Monograph]

    182. Ncgc00260024-01

    183. 2-propanol, 99.95% (lc-ms Grade)

    184. 2-propanol, Uv Hplc Gradient, 99.8%

    185. Isopropyl Alcohol (only Persons Who Manufacture By The Strong Acid Process Are Subject, Supplier Notification Not Required)

    186. Isopropyl Alcohol, Natural, >=98%, Fg

    187. Phenolphthalein Solution, Alcoholic 0.5%

    188. 2-propanol 100 Microg/ml In Acetonitrile

    189. Duraprep Component Isopropyl Alcohol

    190. Isopropyl Alcohol, >=99.7%, Fcc, Fg

    191. Soluprep Component Isopropyl Alcohol

    192. 2-propanol, Saj First Grade, >=99.0%

    193. 2-propanol, Jis Special Grade, >=99.5%

    194. 2-propanol, Laboratory Reagent, >=99.5%

    195. 2-propanol, Meets Usp Testing Specifications

    196. Chloraprep Component Isopropyl Alcohol

    197. Ft-0613371

    198. Ft-0670483

    199. I0163

    200. I0164

    201. I0277

    202. Isopropanol, 99.5% Anhydrous, 50 Ppm Water

    203. Isopropyl Alcohol Component Of Duraprep

    204. Isopropyl Alcohol Component Of Soluprep

    205. C01845

    206. D00137

    207. Q16392

    208. Isopropyl Alcohol Component Of Chloraprep

    209. Sr-01000944474

    210. J-510285

    211. Sr-01000944474-1

    212. 2-propanol, Acs Spectrophotometric Grade, >=99.5%

    213. 2-propanol, P.a., Acs Reagent, Reag. Iso, 99.8%

    214. 2-propanol, Reag. Iso, Uv Hplc Spectroscopic, 99.7%

    215. 2-propanol, Bioreagent, For Molecular Biology, >=99.5%

    216. 2-propanol, Electronic Grade, 99.999% Trace Metals Basis

    217. 2-propanol, Puriss. P.a., Acs Reagent, >=99.8% (gc)

    218. 2-propanol, Vetec(tm) Reagent Grade, Anhydrous, >=99.5%

    219. 2-propanol, Bioultra, For Molecular Biology, >=99.5% (gc)

    220. Isopropanol Or Isopropyl Alcohol [un1219] [flammable Liquid]

    221. Isopropyl Alcohol, Europepharmacopoeia (ep) Reference Standard

    222. Isopropyl Alcohol, Meets Ep, Bp, Usp Testing Specifications

    223. 2-propanol, >=99.7%, Suitable For Absorption Spectrum Analysis

    224. 2-propanol, Semiconductor Grade Puranal(tm) (honeywell 17829)

    225. 2-propanol, United States Pharmacopeia (usp) Reference Standard

    226. 2-propanol, >=99.7%, For Residue Analysis, Suitable For 1000 Per Jis

    227. 2-propanol, Hplc Plus, For Hplc, Gc, And Residue Analysis, 99.9%

    228. 2-propanol, Pharmaceutical Secondary Standard; Certified Reference Material

    229. 2-propanol, Semiconductor Grade Mos Puranal(tm) (honeywell 17930)

    230. 2-propanol, Semiconductor Grade Slsi Puranal(tm) (honeywell 17030)

    231. 2-propanol, Semiconductor Grade Ulsi Puranal(tm) (honeywell 17022)

    232. 2-propanol, Semiconductor Grade Vlsi Puranal(tm) (honeywell 17604)

    233. 2-propanol, Hplc Plus, For Hplc, Gc, And Residue Analysis, 99.9%, Poly Coated Bottles

    234. 2-propanol, Puriss. P.a., Acs Reagent, Reag. Iso, Reag. Ph. Eur., >=99.8% (gc)

    235. 2-propanol, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Usp, >=99.5% (gc)

    236. 8003-15-4

    2.4 Create Date
    2004-09-16
    3 Chemical and Physical Properties
    Molecular Weight 60.10 g/mol
    Molecular Formula C3H8O
    XLogP30.3
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count0
    Exact Mass60.057514874 g/mol
    Monoisotopic Mass60.057514874 g/mol
    Topological Polar Surface Area20.2 Ų
    Heavy Atom Count4
    Formal Charge0
    Complexity10.8
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Therapeutic Uses

    Anti-Infective Agents, Local; Solvents

    National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)

    MEDICATION (VET): Antiseptic, rubefacient

    O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 901

    ALCOHOLS ARE APPLIED TO REDUCE LOCAL BACTERIAL FLORA PRIOR TO PENETRATION WITH NEEDLES OR OTHER SHARP INSTRUMENTS AND AS A PREOPERATIVE WASH. ... ISOPROPYL ALCOHOL HAS SLIGHTLY GREATER BACTERIAL ACTIVITY THAN ETHYL ALCOHOL DUE TO ITS GREATER DEPRESSION OF SURFACE TENSION. IT RAPIDLY KILLS VEGETATIVE FORMS OF MOST BACTERIA WHEN USED FULL STRENGTH OR AS 70% AQ SOLN.

    American Medical Association, Department of Drugs. Drug Evaluations. 6th ed. Chicago, Ill: American Medical Association, 1986., p. 1523

    EXPTL USE: HEPATITIS B VIRUS IN DRIED HUMAN PLASMA WAS EXPOSED FOR 10 MIN AT 20 C TO 70% ISOPROPANOL, A CHEMICAL DISINFECTANT HAVING INTERMEDIATE ACTIVITY LEVEL. ONE CHIMPANZEE RECEIVED TREATED MATERIAL IV, & DID NOT SHOW SIGNS OF INFECTION AFTER POST-INOCULATION PERIOD OF 9 MONTHS.

    PMID:6630443 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270849 BOND WW ET AL; J CLIN MICROBIOL 18 (3): 535 (1983)

    Antiseptic

    O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 901

    4.2 Minimum/Potential Fatal Human Dose

    ACCORDING TO CLINICAL EXPERIENCE ISOPROPYL ALCOHOL IS MORE TOXIC THAN ETHYL ALCOHOL AND LESS TOXIC THAN METHYL ALCOHOL. ... ITS ACUTE POTENCY AS CENTRAL NERVOUS DEPRESSANT IS ABOUT TWICE THAT OF ETHANOL. PROBABLE LETHAL ORAL DOSE FOR ADULT IS 8 OZ (240 ML), BUT AS LITTLE AS 20 ML IN WATER CAN PRODUCE SYMPTOMS.

    Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. III-271

    A single lethal dose for a human is about 250 mL, although as little as 100 mL can be fatal.

    Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 2149

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Solvents

    Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant and Hackh's Chemical Dictionary, 5th ed) (See all compounds classified as Solvents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Cell-mediated Immunity [PE]; Increased Histamine Release [PE]; Standardized Chemical Allergen [EPC]; Allergens [CS]
    5.3 ATC Code

    D - Dermatologicals

    D08 - Antiseptics and disinfectants

    D08A - Antiseptics and disinfectants

    D08AX - Other antiseptics and disinfectants

    D08AX05 - Isopropanol

    5.4 Absorption, Distribution and Excretion

    DISTRIBUTION OF ISOPROPYL ALC ... IN TISSUES OF DOGS 4 HR AFTER ORAL ADMIN OF 90 ML OF ISOPROPYL ALCOHOL WAS DETERMINED ... USING DOGS THAT HAD BEEN GIVEN PROGRESSIVELY INCR AMT OF THE ALCOHOL FOR THE PREVIOUS 59 DAYS. ... CONCENTRATIONS OF ISOPROPYL ALCOHOL FOUND IN THE TISSUES AND BODY FLUIDS DECREASED IN THE FOLLOWING ORDER: BRAIN, URINE, HEART, KIDNEY, AND BLOOD.

    Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4566

    Intestinal uptake of isopropanol is rapid; 80% of an oral dose is absorbed within 30 min. Complete absorption occurs within 2 hr ... . Skin absorption is probably relatively small but contributes to toxicity with prolonged contact. ... Isopropanol distribution in body water with an apparent vol of distribution of 0.6-0.7 L/kg. Two hr are required for complete tissue distribution. ... The kidney excretes 20-50% of an absorbed dose unchanged. Alcohol dehydrogenase oxidizes most isopropanol to acetone, which the lung or kidney slowly eliminates. ... Clinically insignificant excretion occurs into the stomach and saliva.

    Ellenhorn, M.J. and D.G. Barceloux. Medical Toxicology - Diagnosis and Treatment of Human Poisoning. New York, NY: Elsevier Science Publishing Co., Inc. 1988., p. 798

    ABOUT 47% OF ORAL DOSE OF 720 MG ... WAS EXHALED UNCHANGED OVER 3 HR; LESS THAN 3% ... ELIMINATED IN BREATH AS ACETONE ...

    IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V15 235 (1977)

    DISAPPEARANCE RATE OF ISOPROPYL ALC IN BLOOD IS HALF THAT OF ETHANOL BUT 5 TIMES THAT OF METHANOL.

    IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V15 234 (1977)

    For more Absorption, Distribution and Excretion (Complete) data for ISOPROPANOL (12 total), please visit the HSDB record page.

    5.5 Metabolism/Metabolites

    ISOPROPANOL IS OXIDIZED, MORE SLOWLY THAN ETHANOL OR N-PROPANOL, TO ACETONE, & SOME 10% OF DOSE IS EXCRETED BY RABBITS AS GLUCURONIDE CONJUGATE OF ISOPROPANOL.

    Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 214

    METABOLISM OF ETHANOL, PROPANOL, ISOPROPANOL, BUTANOL, ISOBUTANOL, SEC-BUTANOL, & TERT-BUTANOL WAS STUDIED AFTER ORAL ADMIN IN RABBITS. BLOOD PH WAS ON THE ACID SIDE WITH PROPANOL, BUTANOL, & ISOBUTANOL, AND ON THE ALKALINE SIDE WITH ISOPROPANOL & SEC-BUTANOL, BUT NO CHANGE WAS OBSERVED WITH ETHANOL & TERT-BUTANOL. BUTANOL & ISOBUTANOL HAD THE LOWEST RATE OF URINARY EXCRETION. ACETALDEHYDE AND ACETIC ACID WERE DETECTED AS THE URINARY METABOLITES OF ETHANOL AND PROPANOL, WHEREAS ISOBUTYRALDEHYDE & ISOVALERIC ACID WERE THE METABOLITES OF ISOBUTANOL.

    SAITO M; NICHIDAI IGAKU ZASSHI 34 (8-9): 569-85 (1975)

    Alcohol dehydrogenase oxidizes most isopropanol to acetone, which the lung or kidney slowly eliminates. Acetone probably is further metabolized to acetate, formate, and finally carbon dioxide.

    Ellenhorn, M.J. and D.G. Barceloux. Medical Toxicology - Diagnosis and Treatment of Human Poisoning. New York, NY: Elsevier Science Publishing Co., Inc. 1988., p. 798

    Liver alcohol dehydrogonase (ADH) is the major enzyme involved in the oxidation of 2-propanol. ADH oxidizes most 2-propanol to acetone. Acetone then is eliminated from the kidney & expired air. It is estimated that 70-90% of ingested 2-propanol is metabolized to acetone. Acetone is probably further metabolized to acetate, formate & finally carbon dioxide. Conversion of acetone to acetic acid & formic acid may cause acidosis. Metabolism of 2-propanol leads to a shift in NAD/NADH ratio which may cause hypoglycemia.

    Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. Second Edition. Volume 3 Alcohols and Esters. New York, NY: Elsevier, 1992., p. 33

    The metabolism of isopropanol is via oxidation by aldehyde dehydrogenase (ADH) to acetone. In common with other alpha-substituted (secondary) alcohols, isopropanol is a relatively poor substrate for ADH. The primary metabolite, acetone, is eliminated in the expired air and in the urine and also undergoes further oxidation to acetate, formate and ultimately CO2.

    IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V71 1030 (1999)

    2-propanol has known human metabolites that include (2S,3S,4S,5R)-3,4,5-Trihydroxy-6-propan-2-yloxyoxane-2-carboxylic acid.

    S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560

    5.6 Biological Half-Life

    Whole body: 6 hours; whole body for acetone, a metabolite: 22 hours; [TDR, p. 781]

    TDR - Ryan RP, Terry CE, Leffingwell SS (eds). Toxicology Desk Reference: The Toxic Exposure and Medical Monitoring Index, 5th Ed. Washington DC: Taylor & Francis, 1999., p. 781

    ... 1 G/KG WAS INJECTED IV OR INTRAPERITONEALLY IN DOGS AND RATS & PLASMA LEVELS OF ISOPROPYL ALCOHOL & ITS METABOLITE, ACETONE, WERE DETERMINED ... AT INTERVALS. THE MAXIMUM CONCN OF ACETONE WAS 12.4 MMOLES 9 HR AFTER INJECTION ... IN DOGS & 12.0 MMOLES 5 HR AFTER INJECTION IN RATS. ... THE HALF TIME FOR THE ELIMINATION OF ISOPROPYL ALCOHOL BY THE DOG & RAT IS 4 & 2 HR, RESPECTIVELY, & OF ACETONE 11 AND 5/HR.

    Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4567

    In two intoxicated chronic alcoholics, isopropanol elimination exhibited first order kinetics with a half-life of 2.5-3.2 hr. The elimination half-life of ... acetone was more prolonged.

    Ellenhorn, M.J. and D.G. Barceloux. Medical Toxicology - Diagnosis and Treatment of Human Poisoning. New York, NY: Elsevier Science Publishing Co., Inc. 1988., p. 799

    /In/ inhalation of 70% isopropyl alcohol by a neonate ... the isopropyl alcohol elimination half-life was 9.6 hr.

    Ellenhorn, M.J., S. Schonwald, G. Ordog, J. Wasserberger. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams and Wilkins, 1997., p. 1148

    In adults, the elimination half life ranges from 2.9 to 16.2 hours and this is shorter in alcoholics. Values observed in children poisoned with isopropanol fall within this range.

    IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V71 1030 (1999)

    DRUG PRODUCT COMPOSITIONS

    Do you need Business Intel? Ask us

    DOSAGE - SOLUTION;TOPICAL - 2%;70%

    USFDA APPLICATION NUMBER - 208288

    read-more

    DOSAGE - SPONGE;TOPICAL - 2%;70% (1.5ML)

    USFDA APPLICATION NUMBER - 20832

    read-more

    DOSAGE - SPONGE;TOPICAL - 2%;70% (10.5ML)

    USFDA APPLICATION NUMBER - 20832

    read-more

    DOSAGE - SPONGE;TOPICAL - 2%;70% (1ML)

    USFDA APPLICATION NUMBER - 20832

    read-more

    DOSAGE - SPONGE;TOPICAL - 2%;70% (26ML)

    USFDA APPLICATION NUMBER - 20832

    read-more

    DOSAGE - SPONGE;TOPICAL - 2%;70% (3ML)

    USFDA APPLICATION NUMBER - 20832

    read-more

    DOSAGE - SWAB;TOPICAL - 3.15%;70% (1.6ML)

    USFDA APPLICATION NUMBER - 21524

    read-more

    DOSAGE - SWAB;TOPICAL - 3.15%;70% (1ML)

    USFDA APPLICATION NUMBER - 21524

    read-more

    DOSAGE - SWAB;TOPICAL - 3.15%;70% (5.1ML)

    USFDA APPLICATION NUMBER - 21524

    read-more

    DOSAGE - SWAB;TOPICAL - 2%;70% (0.67ML)

    USFDA APPLICATION NUMBER - 21555

    read-more

    DOSAGE - SWAB;TOPICAL - 2%;70% (1.75ML)

    USFDA APPLICATION NUMBER - 21555

    read-more

    DOSAGE - SWAB;TOPICAL - 2%;70% (5.25ML)

    USFDA APPLICATION NUMBER - 21555

    read-more

    DOSAGE - SPONGE;TOPICAL - EQ 0.7% IODINE;74% ...DOSAGE - SPONGE;TOPICAL - EQ 0.7% IODINE;74% (26ML)

    USFDA APPLICATION NUMBER - 21586

    read-more

    DOSAGE - SPONGE;TOPICAL - EQ 0.7% IODINE;74% ...DOSAGE - SPONGE;TOPICAL - EQ 0.7% IODINE;74% (6ML)

    USFDA APPLICATION NUMBER - 21586

    read-more

    Related Excipient Companies

    Upload your portfolio for free, ask us

    Excipients by Applications

    Click here to find the perfect excipient manufacturers by their capabilities

    Topical

    read-more
    read-more

    Parenteral

    read-more
    read-more

    Film Formers & Plasticizers

    read-more
    read-more

    Thickeners and Stabilizers

    read-more
    read-more

    Solubilizers

    read-more
    read-more

    Coating Systems & Additives

    read-more
    read-more

    Fillers, Diluents & Binders

    read-more
    read-more

    Controlled & Modified Release

    read-more
    read-more

    Taste Masking

    read-more
    read-more

    Surfactant & Foaming Agents

    read-more
    read-more

    Chewable & Orodispersible Aids

    read-more
    read-more

    Emulsifying Agents

    read-more
    read-more

    API Stability Enhancers

    read-more
    read-more

    Co-Processed Excipients

    read-more
    read-more

    Granulation

    read-more
    read-more

    Soft Gelatin

    read-more
    read-more

    Direct Compression

    read-more
    read-more

    Lubricants & Glidants

    read-more
    read-more

    Digital Content read-more

    Create Content with PharmaCompass, ask us

    DATA COMPILATION #PharmaFlow

    read-more
    read-more

    NEWS #PharmaBuzz

    read-more
    read-more

    Market Place

    Do you need sourcing support? Ask us

    Patents & EXCLUSIVITIES

    Check the patents & exclusivity for this product

    REF. STANDARDS & IMPURITIES

    Upload your portfolio for free, ask us

    ABOUT THIS PAGE

    Looking for 67-63-0 / Isopropyl Alcohol API manufacturers, exporters & distributors?

    Isopropyl Alcohol manufacturers, exporters & distributors 1

    99

    PharmaCompass offers a list of Isopropyl Alcohol API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Isopropyl Alcohol manufacturer or Isopropyl Alcohol supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Isopropyl Alcohol manufacturer or Isopropyl Alcohol supplier.

    PharmaCompass also assists you with knowing the Isopropyl Alcohol API Price utilized in the formulation of products. Isopropyl Alcohol API Price is not always fixed or binding as the Isopropyl Alcohol Price is obtained through a variety of data sources. The Isopropyl Alcohol Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Isopropyl Alcohol

    Synonyms

    Isopropanol, 2-propanol, Propan-2-ol, 67-63-0, 2-hydroxypropane, Alkolave

    Cas Number

    67-63-0

    Unique Ingredient Identifier (UNII)

    ND2M416302

    About Isopropyl Alcohol

    An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Isopropyl Alcohol Manufacturers

    A Isopropyl Alcohol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Isopropyl Alcohol, including repackagers and relabelers. The FDA regulates Isopropyl Alcohol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Isopropyl Alcohol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Isopropyl Alcohol manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Isopropyl Alcohol Suppliers

    A Isopropyl Alcohol supplier is an individual or a company that provides Isopropyl Alcohol active pharmaceutical ingredient (API) or Isopropyl Alcohol finished formulations upon request. The Isopropyl Alcohol suppliers may include Isopropyl Alcohol API manufacturers, exporters, distributors and traders.

    click here to find a list of Isopropyl Alcohol suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Isopropyl Alcohol USDMF

    A Isopropyl Alcohol DMF (Drug Master File) is a document detailing the whole manufacturing process of Isopropyl Alcohol active pharmaceutical ingredient (API) in detail. Different forms of Isopropyl Alcohol DMFs exist exist since differing nations have different regulations, such as Isopropyl Alcohol USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Isopropyl Alcohol DMF submitted to regulatory agencies in the US is known as a USDMF. Isopropyl Alcohol USDMF includes data on Isopropyl Alcohol's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Isopropyl Alcohol USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Isopropyl Alcohol suppliers with USDMF on PharmaCompass.

    Isopropyl Alcohol KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Isopropyl Alcohol Drug Master File in Korea (Isopropyl Alcohol KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Isopropyl Alcohol. The MFDS reviews the Isopropyl Alcohol KDMF as part of the drug registration process and uses the information provided in the Isopropyl Alcohol KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Isopropyl Alcohol KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Isopropyl Alcohol API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Isopropyl Alcohol suppliers with KDMF on PharmaCompass.

    Isopropyl Alcohol CEP

    A Isopropyl Alcohol CEP of the European Pharmacopoeia monograph is often referred to as a Isopropyl Alcohol Certificate of Suitability (COS). The purpose of a Isopropyl Alcohol CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Isopropyl Alcohol EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Isopropyl Alcohol to their clients by showing that a Isopropyl Alcohol CEP has been issued for it. The manufacturer submits a Isopropyl Alcohol CEP (COS) as part of the market authorization procedure, and it takes on the role of a Isopropyl Alcohol CEP holder for the record. Additionally, the data presented in the Isopropyl Alcohol CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Isopropyl Alcohol DMF.

    A Isopropyl Alcohol CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Isopropyl Alcohol CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Isopropyl Alcohol suppliers with CEP (COS) on PharmaCompass.

    Isopropyl Alcohol GMP

    Isopropyl Alcohol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Isopropyl Alcohol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Isopropyl Alcohol GMP manufacturer or Isopropyl Alcohol GMP API supplier for your needs.

    Isopropyl Alcohol CoA

    A Isopropyl Alcohol CoA (Certificate of Analysis) is a formal document that attests to Isopropyl Alcohol's compliance with Isopropyl Alcohol specifications and serves as a tool for batch-level quality control.

    Isopropyl Alcohol CoA mostly includes findings from lab analyses of a specific batch. For each Isopropyl Alcohol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Isopropyl Alcohol may be tested according to a variety of international standards, such as European Pharmacopoeia (Isopropyl Alcohol EP), Isopropyl Alcohol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Isopropyl Alcohol USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
    Ask Us for Pharmaceutical Supplier and Partner
    Ask Us, Find A Supplier / Partner
    No Commissions, No Strings Attached, Get Connected for FREE

    What are you looking for?

    How can we help you?

    The request can't be empty

    Please read our Privacy Policy carefully

    You must agree to the privacy policy

    The name can't be empty
    The company can't be empty.
    The email can't be empty Please enter a valid email.
    The mobile can't be empty
    • Privacy policy
    • Terms and conditions
    • Disclaimers
    • LinkedIn
    • Product listings are provided for informational purposes only. We do not supply or sell any products. Any products that may be covered by patent(s) are supplied solely for uses permitted under Section 107A of the Indian Patents Act and not for commercial sale.

    Market Place

    Market Place

    PharmaCompass

    Home

    Market Place

    Menu

    Post Enquiry

    Post Enquiry

    Market Place

    Market Place

    Search