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Chemistry

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Also known as: At-007, 2170729-29-8, Govorestat, At007, Govorestat [usan], 6jlq8k35kk
Molecular Formula
C17H10F3N3O3S2
Molecular Weight
425.4  g/mol
InChI Key
ORQGHAJIWGGFJK-UHFFFAOYSA-N
FDA UNII
6JLQ8K35KK

Govorestat
Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
1 2D Structure

Govorestat

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4-oxo-3-[[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl]thieno[3,4-d]pyridazin-1-yl]acetic acid
2.1.2 InChI
InChI=1S/C17H10F3N3O3S2/c18-17(19,20)8-1-2-13-12(3-8)21-14(28-13)5-23-16(26)10-7-27-6-9(10)11(22-23)4-15(24)25/h1-3,6-7H,4-5H2,(H,24,25)
2.1.3 InChI Key
ORQGHAJIWGGFJK-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC2=C(C=C1C(F)(F)F)N=C(S2)CN3C(=O)C4=CSC=C4C(=N3)CC(=O)O
2.2 Other Identifiers
2.2.1 UNII
6JLQ8K35KK
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. At-007

2. 2170729-29-8

3. Govorestat

4. At007

5. Govorestat [usan]

6. 6jlq8k35kk

7. 2-[4-oxo-3-[[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl]thieno[3,4-d]pyridazin-1-yl]acetic Acid

8. Gavorestat

9. Govorestat [inn]

10. Unii-6jlq8k35kk

11. Chembl4650327

12. Schembl19747408

13. Ex-a3180

14. Mfcd32263046

15. Who 11608

16. Zb1621

17. Akos037649079

18. Ac-36354

19. Bs-16512

20. Hy-129586

21. Cs-0106794

22. D81255

23. (4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3,4- Dihydrothieno[3,4-d]pyridazin-1-yl)acetic Acid

24. Thieno[3,4-d]pyridazine-1-acetic Acid, 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-

2.4 Create Date
2018-01-29
3 Chemical and Physical Properties
Molecular Weight 425.4 g/mol
Molecular Formula C17H10F3N3O3S2
XLogP33.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count4
Exact Mass425.01156802 g/mol
Monoisotopic Mass425.01156802 g/mol
Topological Polar Surface Area139 Ų
Heavy Atom Count28
Formal Charge0
Complexity690
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 2170729-29-8 / Govorestat API manufacturers, exporters & distributors?

Govorestat manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Govorestat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Govorestat manufacturer or Govorestat supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Govorestat manufacturer or Govorestat supplier.

PharmaCompass also assists you with knowing the Govorestat API Price utilized in the formulation of products. Govorestat API Price is not always fixed or binding as the Govorestat Price is obtained through a variety of data sources. The Govorestat Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Govorestat

Synonyms

At-007, 2170729-29-8, At007, Govorestat [usan], 6jlq8k35kk, 2-[4-oxo-3-[[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl]thieno[3,4-d]pyridazin-1-yl]acetic acid

Cas Number

2170729-29-8

Unique Ingredient Identifier (UNII)

6JLQ8K35KK

About Govorestat

Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).

Gavorestat Manufacturers

A Gavorestat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Gavorestat, including repackagers and relabelers. The FDA regulates Gavorestat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Gavorestat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Gavorestat Suppliers

A Gavorestat supplier is an individual or a company that provides Gavorestat active pharmaceutical ingredient (API) or Gavorestat finished formulations upon request. The Gavorestat suppliers may include Gavorestat API manufacturers, exporters, distributors and traders.

Gavorestat GMP

Gavorestat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Gavorestat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Gavorestat GMP manufacturer or Gavorestat GMP API supplier for your needs.

Gavorestat CoA

A Gavorestat CoA (Certificate of Analysis) is a formal document that attests to Gavorestat's compliance with Gavorestat specifications and serves as a tool for batch-level quality control.

Gavorestat CoA mostly includes findings from lab analyses of a specific batch. For each Gavorestat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Gavorestat may be tested according to a variety of international standards, such as European Pharmacopoeia (Gavorestat EP), Gavorestat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Gavorestat USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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