Estrogens conjugated

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

17 API Suppliers, 14 USDMF, 1 CEP/COS, 2 EU WC, 1 KDMF, 7 NDC API, 4 Listed Suppliers

DEVELOPMENTS

1 Drug(s) in Development

1 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Imports

DOSSIERs // Finished Dosage Formulations

107 Dossiers, 38 FDA Orange Book, 44 Europe, 10 Canada, 13 South Africa, 2 Listed Dossiers

DRUG PRODUCT COMPOSITION

TABLET;ORAL - EQ 20MG BASE;0.45MG, TABLET;ORAL - 0.3MG, TABLET;ORAL - 0.45MG, TABLET;ORAL - 0.625MG, TABLET;ORAL - 0.9MG, TABLET;ORAL - 1.25MG

TABLET;ORAL - EQ 20MG BASE;0.45MG
TABLET;ORAL - 0.3MG
TABLET;ORAL - 0.45MG
TABLET;ORAL - 0.625MG
TABLET;ORAL - 0.9MG
TABLET;ORAL - 1.25MG

RELATED EXCIPIENT COMPANIES

Suppliers, 30 Kerry, 15 Roquette, 13 Seppic, 11 BASF, 11 Corel Pharma Chem, 10 Microlex e.U, 9 Sigachi Industries, 8 Gangwal Chemicals, 7 Gangwal Healthcare, 6 Lonza Capsugel, 5 Actylis, 5 Ideal Cures Pvt Ltd, 4 SPI Pharma, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 4 DFE Pharma, 4 Kima Chemical, 3 The Dow Chemical Company, 3 Nanjing Well Pharmaceutical, 2 Prachin Chemical, 2 Vasa Pharmachem, 2 Ingredion Pharma Solutions, 2 Nomisma Healthcare, 2 Seqens, 1 ACG Worldwide, 1 Qualicaps, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Pharmatrans-Sanaq, 1 Vertellus, 1 Nanjing Bold Chemical, 1 Finar, 1 Jai Radhe Sales

EXCIPIENTS BY APPLICATIONS

51 Fillers, Diluents & Binders, 43 Coating Systems & Additives, 27 Controlled & Modified Release, 23 Direct Compression, 16 Granulation, 16 Thickeners and Stabilizers, 15 Solubilizers, 12 Co-Processed Excipients, 12 Film Formers & Plasticizers, 10 Disintegrants & Superdisintegrants, 10 Taste Masking, 10 Topical, 10 Lubricants & Glidants, 8 Parenteral, 6 Chewable & Orodispersible Aids, 5 Empty Capsules, 5 Emulsifying Agents, 4 Vegetarian Capsules, 4 API Stability Enhancers, 3 Surfactant & Foaming Agents, 3 Rheology Modifiers, 2 Coloring Agents

GLOBAL SALES INFORMATION

10 US Medicaid Prescriptions, 50 Finished Drug Prices

MARKET PLACE

11 APIs, 1 DOSSIERS // FDF

PATENTS

4 US Patents

4 US Patents

ANALYTICAL SOLUTION(s)

3 EDQM Standards

3 EDQM Standards

DIGITAL CONTENT

4 Data Compilations & Company Tracker #PharmaFlow, 10 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

1,066

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

2,238.00

Annual Reports

FDF Market Place

EXCIPIENTS

174

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: Sodium estrone sulfate, Estrone sodium sulfate, 438-67-5, Estrone sodium sulphate, Estrone 3-sulfate sodium salt, Conestoral

Molecular Formula

C₁₈H₂₁NaO₅S

Molecular Weight

372.4 g/mol

InChI Key

VUCAHVBMSFIGAI-ZFINNJDLSA-M

FDA UNII

6K6FDA543A

1 2D Structure

Estrogens conjugated

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] sulfate

2.1.2 InChI

InChI=1S/C18H22O5S.Na/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);/q;+1/p-1/t14-,15-,16+,18+;/m1./s1

2.1.3 InChI Key

VUCAHVBMSFIGAI-ZFINNJDLSA-M

2.1.4 Canonical SMILES

CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)[O-].[Na+]

2.1.5 Isomeric SMILES

C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)[O-].[Na+]

2.2 Other Identifiers

2.2.1 UNII

6K6FDA543A

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Estrone Sulfate

2. Estrone Sulfate, 14c-labeled

3. Estrone Sulfate, 16-(14)c-labeled

4. Estrone Sulfate, Ammonium Salt

5. Estrone Sulfate, Potassium Salt

6. Estrone Sulfate, Sodium Salt

7. Estrone-3-sulfate

8. Evex

9. Oestrone Sulphate

10. Potassium Estrone Sulfate

11. Sodium Estrone Sulfate

2.3.2 Depositor-Supplied Synonyms

1. Sodium Estrone Sulfate

2. Estrone Sodium Sulfate

3. 438-67-5

4. Estrone Sodium Sulphate

5. Estrone 3-sulfate Sodium Salt

6. Conestoral

7. Hyhorin

8. Morestin

9. Estrone Sulfate Sodium

10. Par Estro

11. Estrone Sulfate Sodium Salt

12. Estrone-3-sulfate Sodium Salt

13. Sodium Estrone Sulphate

14. Sodium Estrone 3-sulfate

15. Oestrone-3-sulphate Sodium Salt

16. Estrogenic Substances (conjugated)

17. Estra-1,3,5(10)-trien-17-one, 3-(sulfooxy)-, Sodium Salt

18. 6k6fda543a

19. Chebi:8389

20. 17-oxoestra-1,3,5(10)-trien-3-yl Sodium Sulfate

21. Nsc-18313

22. Estrone Sulfate (sodium)

23. Sodium;[(8r,9s,13s,14s)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-3-yl] Sulfate

24. Sodium Estrone-3-sulfate

25. 1,3,5(10)-estratrien-3-ol-17-one Sulphate, Sodium Salt

26. Smr000058772

27. Einecs 207-120-4

28. Nsc 18313

29. Unii-6k6fda543a

30. Conjugated Estrogens: Sodium Estrone Sulfate

31. Estrone3-sulfatesodiumsalt

32. Sodium (8r,9s,13s,14s)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopenta(a)phenanthren-3-yl Sulfate

33. Sodium (8r,9s,13s,14s)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopenta[a]phenanthren-3-yl Sulfate

34. Sodium 17-oxoestra-1(10),2,4-trien-3-yl Sulfate

35. Estrone, Hydrogen Sulfate, Sodium Salt

36. Schembl4616

37. Mls000069757

38. Mls001424259

39. Chembl2106240

40. Dtxsid00860005

41. Dtxsid70881181

42. Hms2052j05

43. Hms2232j23

44. Discontinued. See E889070

45. Akos015967195

46. Estrone Sodium Sulfate [vandf]

47. Ccg-101163

48. Hy-113293b

49. Nc00413

50. Estrone Sodium Sulfate [who-dd]

51. Cs-0108249

52. D00312

53. Q4118295

54. Sodium 17-oxoestra-1,3,5(10)-trien-3-yl Sulfate

55. Estrone 3-sulfate Sodium Salt, Stabilized With Tris

56. Estra-1,3,5(10)-trien-17-one 3-(sulfooxy) Sodium Salt

57. Sodium [(8r,9s,13s,14s)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-3-yl] Sulfate

2.4 Create Date

2008-02-05

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₂₁NaO₅S
Molecular Weight	372.4 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	372.10073922 g/mol
Monoisotopic Mass	372.10073922 g/mol
Topological Polar Surface Area	91.9 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	630
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Premarin
PubMed Health	Conjugated Estrogens (By mouth)
Drug Classes	Endocrine-Metabolic Agent, Musculoskeletal Agent
Drug Label	Premarin Intravenous (conjugated estrogens, USP) for injection contains a mixture of conjugated estrogens obtained exclusively from natural sources, occurring as the sodium salts of water-soluble estrogen sulfates blended to represent the average com...
Active Ingredient	Estrogens, conjugated
Dosage Form	Tablet; Cream; Injectable
Route	oral; Injection; Oral; Topical, vaginal
Strength	25mg/vial; 0.45mg; 1.25mg; 0.625mg/gm; 0.625mg; 0.9mg; 0.3mg
Market Status	Prescription
Company	Wyeth Pharms

2 of 2
Drug Name	Premarin
PubMed Health	Conjugated Estrogens (By mouth)
Drug Classes	Endocrine-Metabolic Agent, Musculoskeletal Agent
Drug Label	Premarin Intravenous (conjugated estrogens, USP) for injection contains a mixture of conjugated estrogens obtained exclusively from natural sources, occurring as the sodium salts of water-soluble estrogen sulfates blended to represent the average com...
Active Ingredient	Estrogens, conjugated
Dosage Form	Tablet; Cream; Injectable
Route	oral; Injection; Oral; Topical, vaginal
Strength	25mg/vial; 0.45mg; 1.25mg; 0.625mg/gm; 0.625mg; 0.9mg; 0.3mg
Market Status	Prescription
Company	Wyeth Pharms

Find Conjugated Estrogens manufacturers, exporters & distributors on PharmaCompass

Estrogens Conjugated

Estrogens conjugated

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

17 API Suppliers

14 USDMF

1 CEP/COS

2 EU WC

1 KDMF

7 NDC API

4 Listed Suppliers

DEVELOPMENTS

1 Drug(s) in Development

PRICE INFORMATION

API Reference Price

API Exports

API Imports

FDF Imports

DOSSIERs // Finished Dosage Formulations

107 Dossiers

38 FDA Orange Book

44 Europe

10 Canada

13 South Africa

2 Listed Dossiers

DRUG PRODUCT COMPOSITION

TABLET;ORAL - EQ 20MG BASE;0.45MG

TABLET;ORAL - 0.3MG

TABLET;ORAL - 0.45MG

TABLET;ORAL - 0.625MG

TABLET;ORAL - 0.9MG

TABLET;ORAL - 1.25MG

RELATED EXCIPIENT COMPANIES

Suppliers

30 Kerry

15 Roquette

13 Seppic

11 BASF

11 Corel Pharma Chem

10 Microlex e.U

9 Sigachi Industries

8 Gangwal Chemicals

7 Gangwal Healthcare

6 Lonza Capsugel

5 Actylis

5 Ideal Cures Pvt Ltd

4 SPI Pharma

4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

4 DFE Pharma

4 Kima Chemical

3 The Dow Chemical Company

3 Nanjing Well Pharmaceutical

2 Prachin Chemical

2 Vasa Pharmachem

2 Ingredion Pharma Solutions

2 Nomisma Healthcare

2 Seqens

1 ACG Worldwide

1 Qualicaps

1 Qianhao Chemical (Hebei) Co., Ltd

1 Pharmatrans-Sanaq

1 Vertellus

1 Nanjing Bold Chemical

1 Finar

1 Jai Radhe Sales

EXCIPIENTS BY APPLICATIONS

51 Fillers, Diluents & Binders

43 Coating Systems & Additives

27 Controlled & Modified Release

23 Direct Compression

16 Granulation

16 Thickeners and Stabilizers

15 Solubilizers

12 Co-Processed Excipients

12 Film Formers & Plasticizers

10 Disintegrants & Superdisintegrants

10 Taste Masking