Synopsis
Synopsis
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CEP/COS
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0
EU WC
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KDMF
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NDC API
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USP
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JP
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Europe
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1. (1s)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo(2,1-f)(1,2,4)triazin-4-yl)-1-piperazinyl)-5-pyrimidinyl)ethanamine
2. 5-pyrimidinemethanamine, Alpha-(4-fluorophenyl)-alpha-methyl-2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo(2,1-f)(1,2,4)triazin-4-yl)-1-piperazinyl)-, (alphas)-
3. Ayvakit
4. Blu-285
1. Blu-285
2. 1703793-34-3
3. Ayvakit
4. Avapritinib [inn]
5. Blu285
6. (1s)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine
7. 513p80b4yj
8. C-366
9. 70c366
10. X720776
11. X-720776
12. Ayvakyt
13. Mfcd31544325
14. Ayvakit (tn)
15. Avapritinib [mi]
16. Avapritinib (usan/inn)
17. Avapritinib [usan]
18. Avapritinib (blu-285)
19. Blu-285 (avapritinib)
20. Avapritinib [who-dd]
21. Unii-513p80b4yj
22. Chembl4204794
23. Schembl16652297
24. Gtpl10368
25. Avapritinib [orange Book]
26. Blu 285
27. Bdbm469269
28. Dtxsid301027935
29. Amy16753
30. Ex-a1366
31. Us10807985, Compound 44
32. Nsc801082
33. S8553
34. Akos037648993
35. Ccg-269677
36. Cs-7577
37. Db15233
38. Nsc-801082
39. (s)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine
40. Ac-31598
41. Bb166456
42. Bs-16206
43. Hy-101561
44. D11279
45. Q29213676
46. (1s)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo(2,1-f)(1,2,4)triazin-4-yl)-1-piperazinyl)-5-pyrimidinyl)ethanamine
47. (1s)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo(2,1-f)(1,2,4)triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine
48. (s)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo(2,1-f)(1,2,4)triazin-4-yl)piperazin-yl)pyrimidin-5-yl)ethan-1-amine
49. (s)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)ethanamine
50. 5-pyrimidinemethanamine, .alpha.-(4-fluorophenyl)-.alpha.-methyl-2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo(2,1-f)(1,2,4)triazin-4-yl)-1-piperazinyl)-, (.alpha.s)-
Molecular Weight | 498.6 g/mol |
---|---|
Molecular Formula | C26H27FN10 |
XLogP3 | 1.9 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 9 |
Rotatable Bond Count | 5 |
Exact Mass | 498.24041907 g/mol |
Monoisotopic Mass | 498.24041907 g/mol |
Topological Polar Surface Area | 106 Ų |
Heavy Atom Count | 37 |
Formal Charge | 0 |
Complexity | 752 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 1 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Avapritinib is indicated for the treatment of unresectable, metastatic gastrointestinal stromal tumors with a platelet-derived growth factor receptor alpha exon 18 mutation.
Treatment of mastocytosis
Treatment of all conditions included in the category of malignant neoplasms (except haematopoietic and lymphoid tissue neoplasms)
Ayvakyt is indicated as monotherapy for the treatment of adult patients with unresectable or metastatic gastrointestinal stromal tumours (GIST) harbouring the platelet-derived growth factor receptor alpha (PDGFRA) D842V mutation.
Avapritinib is a selective kinase inhibitor that negatively modulates the action of cell transporters to resensitize them to other chemotherapies. It has a long duration of action as it is given once daily. Patients should be counselled regarding the risk of intracranial hemorrhage, CNS effects, and embryo-fetal toxicity.
L01EX18
L - Antineoplastic and immunomodulating agents
L01 - Antineoplastic agents
L01E - Protein kinase inhibitors
L01EX - Other protein kinase inhibitors
L01EX18 - Avapritinib
Absorption
A 300mg oral dose of avapritinib reaches a Cmax of 813ng/mL with a Tmax of 2.0-4.1h and an AUC of 15400h\*ng/mL.
Route of Elimination
Avapritinib is 70% eliminated in the feces with 11% as the unchanged drug and 18% eliminated in the urine with 0.23% as the unchanged drug.
Volume of Distribution
The mean apparent volume of distribution is 1200L.
Clearance
The mean apparent oral clearance of avapritinib is 19.5L/h.
Avapritinib is metabolized mainly by CYP3A4 and CYP2C9 in vitro. A 310mg oral dose is recovered as 49% unchanged drug, 35% hydroxy glucuronide metabolite, and 14% oxidatively deaminated metabolite.
The half life of avapritinib is 32-57h.
Avapritinib has a negative modulating effect on the transporters ABCB1 and ABCG2, which mediate the multidrug resistance phenotype of some cancers. This modulation may be due to interactions of avapritinib with the drug binding pocket of these transporters. Negative modulation of these transporters, resensitizes cancerous cells to treatment with chemotherapeutic agents like [paclitaxel].
Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.
TAPI, a leading global supplier of APIs, provides over 350 products and customized CDMO solutions for every stage of development.
Details:
Ayvakyt (avapritinib) is a kinase inhibitor, works by potently and selectively target KIT D816V. It is approved by european commission for the treatment of indolent systemic mastocytosis (ISM).
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakyt
Study Phase: Approved FDFProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 13, 2023
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
EC Approves Treatment for Rare Haematological Disorder
Details : Ayvakyt (avapritinib) is a kinase inhibitor, works by potently and selectively target KIT D816V. It is approved by european commission for the treatment of indolent systemic mastocytosis (ISM).
Product Name : Ayvakyt
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 13, 2023
Details:
AYVAKYT® (avapritinib) is a kinase inhibitor approved by the European Commission for the treatment of adult patients with aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematological neoplasm (SM-AHN) or mast cell leukemia (MCL).
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Approved FDFProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable October 11, 2023
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Blueprint Medicines' AYVAKYT® (avapritinib) Receives Positive CHMP Opinion as the First and Only ...
Details : AYVAKYT® (avapritinib) is a kinase inhibitor approved by the European Commission for the treatment of adult patients with aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematological neoplasm (SM-AHN) or mast cell leuke...
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 11, 2023
Details:
Ayvakit (avapritinib) is a FDA approved kinase inhibitor for treatment adults with Indolent Systemic Mastocytosis, ASM, SM-AHN and MCL, also for adults with GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Approved FDFProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable May 22, 2023
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Approves AYVAKIT® (avapritinib) as the First and Only Treatment for Indolent Systemic Mastocy...
Details : Ayvakit (avapritinib) is a FDA approved kinase inhibitor for treatment adults with Indolent Systemic Mastocytosis, ASM, SM-AHN and MCL, also for adults with GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 22, 2023
Details:
Ayvakit (avapritinib) is a kinase inhibitor approved by the FDA for the treatment of adults with Advanced SM, ASM, SM-AHN and MCL, and adults with unresectable or metastatic GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Phase IIIProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable March 02, 2023
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Blueprint Medicines to Present Positive Data from PIONEER Trial of AYVAKIT® (avapritinib) in Indo...
Details : Ayvakit (avapritinib) is a kinase inhibitor approved by the FDA for the treatment of adults with Advanced SM, ASM, SM-AHN and MCL, and adults with unresectable or metastatic GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 02, 2023
Details:
Ayvakit (avapritinib) is a kinase inhibitor approved by the FDA for the treatment of adults with Advanced SM, ASM, SM-AHN and MCL, and adults with unresectable or metastatic GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Approved FDFProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable February 14, 2023
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
CStone Announces Precision Medicine Avapritinib (ayvakit®) Recommended in China’s First “chin...
Details : Ayvakit (avapritinib) is a kinase inhibitor approved by the FDA for the treatment of adults with Advanced SM, ASM, SM-AHN and MCL, and adults with unresectable or metastatic GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 14, 2023
Details:
Ayvakit (avapritinib) is a kinase inhibitor approved by the FDA for the treatment of adults with Advanced SM, ASM, SM-AHN and MCL, and adults with unresectable or metastatic GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Phase IIIProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable January 23, 2023
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Blueprint Medicines Announces FDA Acceptance of Supplemental New Drug Application for Ayvakit® (a...
Details : Ayvakit (avapritinib) is a kinase inhibitor approved by the FDA for the treatment of adults with Advanced SM, ASM, SM-AHN and MCL, and adults with unresectable or metastatic GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 23, 2023
Details:
AYVAKIT (avapritinib) is a kinase inhibitor approved by the FDA for the treatment of adults with Advanced SM, including aggressive SM (ASM), SM with an associated hematological neoplasm (SM-AHN) and mast cell leukemia (MCL).
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Phase IIIProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 22, 2022
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Blueprint Medicines Submits Supplemental New Drug Application to FDA for AYVAKIT® (avapritinib) f...
Details : AYVAKIT (avapritinib) is a kinase inhibitor approved by the FDA for the treatment of adults with Advanced SM, including aggressive SM (ASM), SM with an associated hematological neoplasm (SM-AHN) and mast cell leukemia (MCL).
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 22, 2022
Details:
Ayvakit (avapritinib) is a FDA approved kinase inhibitor for treatment adults with Advanced SM, ASM, SM-AHN and MCL, also for adults with GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Phase IIProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 12, 2022
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Ayvakit (avapritinib) is a FDA approved kinase inhibitor for treatment adults with Advanced SM, ASM, SM-AHN and MCL, also for adults with GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 12, 2022
Details:
Primary endpoint of PIONEER trial of AYVAKIT (Avapritinib) in non-advanced SM to be updated to mean change in total symptom score, previously a key secondary endpoint, based on U.S. FDA recommendation.
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Approved FDFProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable September 06, 2022
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Blueprint Medicines Slips as It Changes Endpoint for Trial in Aim to Greatly Broaden Ayvakit Label
Details : Primary endpoint of PIONEER trial of AYVAKIT (Avapritinib) in non-advanced SM to be updated to mean change in total symptom score, previously a key secondary endpoint, based on U.S. FDA recommendation.
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 06, 2022
Details:
The trial, which was designed to assess AYVAKIT (avapritinib) plus best available care versus placebo plus best available care (control arm), achieved its primary endpoint with a highly significant difference in the mean change in total symptom score at 24 weeks (p=0.003).
Lead Product(s): Avapritinib
Therapeutic Area: Hematology Brand Name: Ayvakit
Study Phase: Approved FDFProduct Type: Other Small Molecule
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable August 17, 2022
Lead Product(s) : Avapritinib
Therapeutic Area : Hematology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Blueprint Medicines Announces Positive Top-line Results from PIONEER Trial of AYVAKIT® (avapritin...
Details : The trial, which was designed to assess AYVAKIT (avapritinib) plus best available care versus placebo plus best available care (control arm), achieved its primary endpoint with a highly significant difference in the mean change in total symptom score at ...
Product Name : Ayvakit
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 17, 2022
Ethyl 2-chloropyrimidine-5-carboxylate
CAS Number : 89793-12-4
End Use API : Avapritinib
About The Company : LinkChem is a leading China headquartered CMO | CRO provider within the pharmaceutical industry. Our core focus includes: custom synthesis, process development,...
Regulatory Info : RX
Registration Country : USA
Brand Name : AYVAKIT
Dosage Form : TABLET;ORAL
Dosage Strength : 100MG
Packaging :
Approval Date : 2020-01-09
Application Number : 212608
Regulatory Info : RX
Registration Country : USA
Regulatory Info : RX
Registration Country : USA
Brand Name : AYVAKIT
Dosage Form : TABLET;ORAL
Dosage Strength : 200MG
Packaging :
Approval Date : 2020-01-09
Application Number : 212608
Regulatory Info : RX
Registration Country : USA
Regulatory Info : RX
Registration Country : USA
Brand Name : AYVAKIT
Dosage Form : TABLET;ORAL
Dosage Strength : 300MG
Packaging :
Approval Date : 2020-01-09
Application Number : 212608
Regulatory Info : RX
Registration Country : USA
Regulatory Info : RX
Registration Country : USA
Brand Name : AYVAKIT
Dosage Form : TABLET;ORAL
Dosage Strength : 25MG
Packaging :
Approval Date : 2021-06-16
Application Number : 212608
Regulatory Info : RX
Registration Country : USA
Regulatory Info : RX
Registration Country : USA
Brand Name : AYVAKIT
Dosage Form : TABLET;ORAL
Dosage Strength : 50MG
Packaging :
Approval Date : 2021-06-16
Application Number : 212608
Regulatory Info : RX
Registration Country : USA
Regulatory Info : Prescription
Registration Country : Canada
Brand Name : AYVAKYT
Dosage Form : TABLET
Dosage Strength : 25MG
Packaging :
Approval Date :
Application Number : 2551764
Regulatory Info : Prescription
Registration Country : Canada
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Regulatory Info : Prescription
Registration Country : Canada
Brand Name : AYVAKYT
Dosage Form : TABLET
Dosage Strength : 50MG
Packaging :
Approval Date :
Application Number : 2551772
Regulatory Info : Prescription
Registration Country : Canada
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Regulatory Info : Prescription
Registration Country : Canada
Brand Name : AYVAKYT
Dosage Form : TABLET
Dosage Strength : 100MG
Packaging :
Approval Date :
Application Number : 2551780
Regulatory Info : Prescription
Registration Country : Canada
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Regulatory Info : Prescription
Registration Country : Canada
Brand Name : AYVAKYT
Dosage Form : TABLET
Dosage Strength : 200MG
Packaging :
Approval Date :
Application Number : 2551799
Regulatory Info : Prescription
Registration Country : Canada
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
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PharmaCompass offers a list of Avapritinib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Avapritinib manufacturer or Avapritinib supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Avapritinib manufacturer or Avapritinib supplier.
PharmaCompass also assists you with knowing the Avapritinib API Price utilized in the formulation of products. Avapritinib API Price is not always fixed or binding as the Avapritinib Price is obtained through a variety of data sources. The Avapritinib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A BLU-285 (Avapritinib) manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of BLU-285 (Avapritinib), including repackagers and relabelers. The FDA regulates BLU-285 (Avapritinib) manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. BLU-285 (Avapritinib) API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of BLU-285 (Avapritinib) manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A BLU-285 (Avapritinib) supplier is an individual or a company that provides BLU-285 (Avapritinib) active pharmaceutical ingredient (API) or BLU-285 (Avapritinib) finished formulations upon request. The BLU-285 (Avapritinib) suppliers may include BLU-285 (Avapritinib) API manufacturers, exporters, distributors and traders.
click here to find a list of BLU-285 (Avapritinib) suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
BLU-285 (Avapritinib) Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of BLU-285 (Avapritinib) GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right BLU-285 (Avapritinib) GMP manufacturer or BLU-285 (Avapritinib) GMP API supplier for your needs.
A BLU-285 (Avapritinib) CoA (Certificate of Analysis) is a formal document that attests to BLU-285 (Avapritinib)'s compliance with BLU-285 (Avapritinib) specifications and serves as a tool for batch-level quality control.
BLU-285 (Avapritinib) CoA mostly includes findings from lab analyses of a specific batch. For each BLU-285 (Avapritinib) CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
BLU-285 (Avapritinib) may be tested according to a variety of international standards, such as European Pharmacopoeia (BLU-285 (Avapritinib) EP), BLU-285 (Avapritinib) JP (Japanese Pharmacopeia) and the US Pharmacopoeia (BLU-285 (Avapritinib) USP).