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Chemistry

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Also known as: Azepane, 111-49-9, Hexahydroazepine, Perhydroazepine, Homopiperidine, Hexamethylenimine
Molecular Formula
C6H13N
Molecular Weight
99.17  g/mol
InChI Key
ZSIQJIWKELUFRJ-UHFFFAOYSA-N
FDA UNII
CZD076G73R

Hexahydroazepine
1 2D Structure

Hexahydroazepine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
azepane
2.1.2 InChI
InChI=1S/C6H13N/c1-2-4-6-7-5-3-1/h7H,1-6H2
2.1.3 InChI Key
ZSIQJIWKELUFRJ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CCCNCC1
2.2 Other Identifiers
2.2.1 UNII
CZD076G73R
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hexahydroazepine

2. Hexahydroazepine Hydrochloride

3. Perhydroazepine

2.3.2 Depositor-Supplied Synonyms

1. Azepane

2. 111-49-9

3. Hexahydroazepine

4. Perhydroazepine

5. Homopiperidine

6. Hexamethylenimine

7. Hexahydro-1h-azepine

8. 1h-azepine, Hexahydro-

9. Azacycloheptane

10. 1-azacycloheptane

11. Azepan

12. Cyclohexamethylenimine

13. Hexamethylene Imine

14. Azepine, Hexahydro-

15. Nsc 16236

16. Mfcd00006934

17. Czd076g73r

18. G 0

19. Chebi:32616

20. Nsc-16236

21. Dsstox_cid_6879

22. Dsstox_rid_78234

23. Dsstox_gsid_26879

24. Cycloheptane, 1-aza-

25. Cas-111-49-9

26. Hsdb 562

27. Einecs 203-875-9

28. Un2493

29. Brn 0001084

30. Unii-czd076g73r

31. Cp 18407

32. Ai3-26610

33. Ccris 8886

34. Azepane #

35. Hexamethyleneimine, 99%

36. Wln: T7mtj

37. Hexamethylene Imine (hmi)

38. Ec 203-875-9

39. 5-20-04-00003 (beilstein Handbook Reference)

40. Chembl1375444

41. Dtxsid1026879

42. Hexamethyleneimine [hsdb]

43. 2,3,4,5,6,7-hexahydroazepine

44. Act03374

45. Cs-b0958

46. Nsc16236

47. Str01425

48. Zinc3636476

49. Tox21_201482

50. Tox21_303304

51. Stl124104

52. Akos000119078

53. Un 2493

54. 2,3,4,5,6,7-hexahydro-1h-azepine

55. Ncgc00091040-01

56. Ncgc00091040-02

57. Ncgc00257117-01

58. Ncgc00259033-01

59. Bp-30036

60. H0092

61. D77224

62. Hexamethyleneimine [un2493] [flammable Liquid]

63. Q421530

64. J-002592

65. J-521455

66. Z57127566

67. F2190-0324

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 99.17 g/mol
Molecular Formula C6H13N
XLogP31.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass99.104799419 g/mol
Monoisotopic Mass99.104799419 g/mol
Topological Polar Surface Area12 Ų
Heavy Atom Count7
Formal Charge0
Complexity37.4
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Metabolism/Metabolites

HEXAMETHYLENEIMINE WAS FOUND TO BE A URINARY METABOLITE OF THE CARCINOGEN N-NITROSOHEXAMETHYLENEIMINE IN MALE RATS.

GRANDJEAN CJ; METABOLISM OF N-NITROSOHEXAMETHYLENEIMINE; J NATL CANCER INST 57(1) 181 (1976)


HEXAMETHYLENIMINE WAS FOUND TO BE A URINARY METABOLITE OF PIVMECILLINAM IN HUMANS.

HATTORI M ET AL; METABOLITES OF PIVMECILLINAM IN HUMAN URINE; CHEMOTHERAPY (TOKYO) 25(1) 123 (1977)


API Reference Price

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11-May-2023
11-Dec-2024
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ABOUT THIS PAGE

Looking for 111-49-9 / Hexahydroazepine API manufacturers, exporters & distributors?

Hexahydroazepine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Hexahydroazepine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Hexahydroazepine manufacturer or Hexahydroazepine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Hexahydroazepine manufacturer or Hexahydroazepine supplier.

PharmaCompass also assists you with knowing the Hexahydroazepine API Price utilized in the formulation of products. Hexahydroazepine API Price is not always fixed or binding as the Hexahydroazepine Price is obtained through a variety of data sources. The Hexahydroazepine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Hexahydroazepine

Synonyms

Azepane, 111-49-9, Perhydroazepine, Homopiperidine, Hexamethylenimine, Hexahydro-1h-azepine

Cas Number

111-49-9

Unique Ingredient Identifier (UNII)

CZD076G73R

AZEPAN Manufacturers

A AZEPAN manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of AZEPAN, including repackagers and relabelers. The FDA regulates AZEPAN manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. AZEPAN API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

AZEPAN Suppliers

A AZEPAN supplier is an individual or a company that provides AZEPAN active pharmaceutical ingredient (API) or AZEPAN finished formulations upon request. The AZEPAN suppliers may include AZEPAN API manufacturers, exporters, distributors and traders.

click here to find a list of AZEPAN suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

AZEPAN USDMF

A AZEPAN DMF (Drug Master File) is a document detailing the whole manufacturing process of AZEPAN active pharmaceutical ingredient (API) in detail. Different forms of AZEPAN DMFs exist exist since differing nations have different regulations, such as AZEPAN USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A AZEPAN DMF submitted to regulatory agencies in the US is known as a USDMF. AZEPAN USDMF includes data on AZEPAN's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The AZEPAN USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of AZEPAN suppliers with USDMF on PharmaCompass.

AZEPAN GMP

AZEPAN Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of AZEPAN GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right AZEPAN GMP manufacturer or AZEPAN GMP API supplier for your needs.

AZEPAN CoA

A AZEPAN CoA (Certificate of Analysis) is a formal document that attests to AZEPAN's compliance with AZEPAN specifications and serves as a tool for batch-level quality control.

AZEPAN CoA mostly includes findings from lab analyses of a specific batch. For each AZEPAN CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

AZEPAN may be tested according to a variety of international standards, such as European Pharmacopoeia (AZEPAN EP), AZEPAN JP (Japanese Pharmacopeia) and the US Pharmacopoeia (AZEPAN USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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