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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: Qinghaosu, 63968-64-9, Huanghuahaosu, Artemisinine, Artemisine, (+)-artemisinin
Molecular Formula
C15H22O5
Molecular Weight
282.33  g/mol
InChI Key
BLUAFEHZUWYNDE-NNWCWBAJSA-N
FDA UNII
9RMU91N5K2

Artemisinin
(+)-artemisinin is a natural product found in Microliabum polymnioides, Artemisia tenuisecta, and other organisms with data available.
1 2D Structure

Artemisinin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one
2.1.2 InChI
InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
2.1.3 InChI Key
BLUAFEHZUWYNDE-NNWCWBAJSA-N
2.1.4 Canonical SMILES
CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C
2.1.5 Isomeric SMILES
C[C@@H]1CC[C@H]2[C@H](C(=O)O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)C
2.2 Other Identifiers
2.2.1 UNII
9RMU91N5K2
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (3r,5as,6r,8as,9r,12s,12ar)-3,6,9-trimethyloctahydro-3,12-epoxypyrano(4,3-j)-1,2-benzodioxepin-10(3h)-one

2. Arteannuin

3. Artemisinine

4. Artemisininum

5. Huanghuahaosu

6. Qing Hao Su

7. Qinghaosu

8. Quing Hau Sau

9. Quinghaosu

2.3.2 Depositor-Supplied Synonyms

1. Qinghaosu

2. 63968-64-9

3. Huanghuahaosu

4. Artemisinine

5. Artemisine

6. (+)-artemisinin

7. Artemisinina

8. Artemisininum

9. Artemisinin [inn]

10. Qing Hau Sau

11. Nsc 369397

12. Chebi:223316

13. Octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin-10(3h)-one

14. 9rmu91n5k2

15. Qinghosu

16. Quing Hau Sau

17. Astemisinin

18. (1r,4s,5r,8s,9r,12s,13r)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one

19. (3r,5as,6r,8as,9r,12s,12ar)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3h)-one

20. (3r,5as,6r,8as,9r,12s,12ar)-octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin-10(3h)-one

21. Qing Hau Su

22. Qinghaosu [chinese]

23. Artemisinine [french]

24. Artemisininum [latin]

25. Artemisinina [spanish]

26. (+)-arteannuin

27. Qing Hau Sau [chinese]

28. Mfcd00081057

29. Artemisia Annua L., Extract

30. (1r,4s,5r,8s,9r,12s,13r)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-one

31. (3r,5as,6r,8as,9r,12s,12ar)-3,6,9-trimethyloctahydro-3,12-epoxypyrano(4,3-j)(1,2)benzodioxepin-10(3h)-one

32. (3r,5as,6r,8as,9r,12s,12ar)-octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j]-1,2-benzodioxepin-10(3h)-one

33. 1,5,9-trimethyl-(1r,4s,5r,9r,12s,13r)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one

34. Smr000578089

35. Sr-01000802560

36. Gnf-pf-5341

37. Artemsinin

38. Brn 4194670

39. Unii-9rmu91n5k2

40. Artemesinin

41. Artesin

42. Nsc-369397

43. Qinghaosu,artemisinine

44. Spectrum_001351

45. Artemisinin [mi]

46. Prestwick0_000498

47. Prestwick1_000498

48. Prestwick2_000498

49. Prestwick3_000498

50. Spectrum2_001512

51. Spectrum3_001549

52. Spectrum4_000721

53. Spectrum5_001098

54. Artemisinin [inci]

55. Ec 700-290-5

56. Artemisinin [mart.]

57. Schembl60304

58. Artemisinin [usp-rs]

59. Artemisinin [who-dd]

60. Artemisinin [who-ip]

61. Bspbio_000395

62. Bspbio_002998

63. Kbiogr_000982

64. Kbioss_001831

65. Mls001097650

66. Mls001304036

67. Mls002153846

68. Divk1c_000656

69. Spbio_001583

70. Spbio_002316

71. Bpbio1_000435

72. Chembl269671

73. Gtpl9954

74. Dtxsid2040652

75. Kbio1_000656

76. Kbio2_001831

77. Kbio2_004399

78. Kbio2_006967

79. Kbio3_002498

80. Ninds_000656

81. Hms2090i17

82. Hms2096d17

83. Hms2267n09

84. Hms3269l13

85. Hms3413p13

86. Hms3677p13

87. Hms3713d17

88. Pharmakon1600-01503042

89. 3,12-epoxy-12h-pyrano[4,3-j]-1,2-benzodioxepin-10(3h)-one, Octahydro-3,6,9-trimethyl-, (3r,5as,6r,8as,9r,12s,12ar)-

90. Bcp02096

91. Hy-b0094

92. Zinc8143788

93. Artemisininum [who-ip Latin]

94. Bdbm50088447

95. Nsc758216

96. Akos024457231

97. Ccg-220498

98. Cs-1794

99. Db13132

100. Lmpr0103190003

101. Nsc-758216

102. Idi1_000656

103. (3r,5as,6r,8as,9r,12s,12ar)-3,6,9-trimethyloctahydro-12h-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3h)-one

104. 3,12-epoxy-12h-pyranol(4,3-j)-1,2-benzodioxepin-10(3h)-one, Octahydro-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12ar*)-(+)-

105. As-12692

106. S1282

107. 968a649

108. Q426921

109. Sr-01000802560-2

110. Sr-01000802560-3

111. Sr-01000802560-4

112. Brd-k13112821-001-08-3

113. Brd-k13112821-001-17-4

114. 2ab44f63-5d0f-424a-aa3f-24062f9c1ced

115. (3r,5as,6r,8as,9r,12s,12ar)-3,6,9-trimethyloctahydro-3,12-epoxypyrano(4,3-j )-1,2-benzodioxepin-10(3h)-one

116. (3r,5as,6r,8as,9r,12s,12ar)-3,6,9-trimethyloctahydro-3h-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(12h)-one

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 282.33 g/mol
Molecular Formula C15H22O5
XLogP32.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass282.14672380 g/mol
Monoisotopic Mass282.14672380 g/mol
Topological Polar Surface Area54 Ų
Heavy Atom Count20
Formal Charge0
Complexity452
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)


4.2 ATC Code

P - Antiparasitic products, insecticides and repellents

P01 - Antiprotozoals

P01B - Antimalarials

P01BE - Artemisinin and derivatives, plain

P01BE01 - Artemisinin


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ABOUT THIS PAGE

Looking for 63968-64-9 / Artemisinin API manufacturers, exporters & distributors?

Artemisinin manufacturers, exporters & distributors 1

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API | Excipient name

Artemisinin

Synonyms

Qinghaosu, 63968-64-9, Huanghuahaosu, Artemisinine, Artemisine, (+)-artemisinin

Cas Number

63968-64-9

Unique Ingredient Identifier (UNII)

9RMU91N5K2

About Artemisinin

(+)-artemisinin is a natural product found in Microliabum polymnioides, Artemisia tenuisecta, and other organisms with data available.

ATM; Manufacturers

A ATM; manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of ATM;, including repackagers and relabelers. The FDA regulates ATM; manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. ATM; API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of ATM; manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

ATM; Suppliers

A ATM; supplier is an individual or a company that provides ATM; active pharmaceutical ingredient (API) or ATM; finished formulations upon request. The ATM; suppliers may include ATM; API manufacturers, exporters, distributors and traders.

click here to find a list of ATM; suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

ATM; GMP

ATM; Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of ATM; GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right ATM; GMP manufacturer or ATM; GMP API supplier for your needs.

ATM; CoA

A ATM; CoA (Certificate of Analysis) is a formal document that attests to ATM;'s compliance with ATM; specifications and serves as a tool for batch-level quality control.

ATM; CoA mostly includes findings from lab analyses of a specific batch. For each ATM; CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

ATM; may be tested according to a variety of international standards, such as European Pharmacopoeia (ATM; EP), ATM; JP (Japanese Pharmacopeia) and the US Pharmacopoeia (ATM; USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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