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Chemistry

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Also known as: Acetylsalicylic acid, 50-78-2, 2-acetoxybenzoic acid, 2-(acetyloxy)benzoic acid, O-acetylsalicylic acid, Acetylsalicylate
Molecular Formula
C9H8O4
Molecular Weight
180.16  g/mol
InChI Key
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
FDA UNII
R16CO5Y76E

Aspirin
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Aspirin is a Nonsteroidal Anti-inflammatory Drug and Platelet Aggregation Inhibitor. The mechanism of action of aspirin is as a Cyclooxygenase Inhibitor. The physiologic effect of aspirin is by means of Decreased Prostaglandin Production and Decreased Platelet Aggregation.
1 2D Structure

Aspirin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-acetyloxybenzoic acid
2.1.2 InChI
InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
2.1.3 InChI Key
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(=O)OC1=CC=CC=C1C(=O)O
2.2 Other Identifiers
2.2.1 UNII
R16CO5Y76E
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(acetyloxy)benzoic Acid

2. Acetylsalicylic Acid

3. Acetysal

4. Acid, Acetylsalicylic

5. Acylpyrin

6. Aloxiprimum

7. Colfarit

8. Dispril

9. Easprin

10. Ecotrin

11. Endosprin

12. Magnecyl

13. Micristin

14. Polopirin

15. Polopiryna

16. Solprin

17. Solupsan

18. Zorprin

2.3.2 Depositor-Supplied Synonyms

1. Acetylsalicylic Acid

2. 50-78-2

3. 2-acetoxybenzoic Acid

4. 2-(acetyloxy)benzoic Acid

5. O-acetylsalicylic Acid

6. Acetylsalicylate

7. O-acetoxybenzoic Acid

8. Acylpyrin

9. Easprin

10. Ecotrin

11. Salicylic Acid Acetate

12. Acenterine

13. Acetophen

14. Polopiryna

15. Acetosal

16. Colfarit

17. O-carboxyphenyl Acetate

18. Acidum Acetylsalicylicum

19. Enterosarein

20. Aceticyl

21. Acetonyl

22. Acetosalin

23. Acetylin

24. Aspergum

25. Aspirdrops

26. Benaspir

27. Measurin

28. Micristin

29. Pharmacin

30. Premaspin

31. Salcetogen

32. Temperal

33. Ecolen

34. Empirin

35. Endydol

36. Rhodine

37. Saletin

38. Rheumintabletten

39. Solprin Acid

40. 2-acetyloxybenzoic Acid

41. Benzoic Acid, 2-(acetyloxy)-

42. Acetisal

43. Acetylsal

44. Aspirine

45. Bialpirina

46. Bialpirinia

47. Claradin

48. Clariprin

49. Entericin

50. Enterophen

51. Enterosarine

52. Globentyl

53. Neuronika

54. Salacetin

55. Solpyron

56. Acesal

57. Acisal

58. Asagran

59. Asteric

60. Cemirit

61. Decaten

62. Duramax

63. Extren

64. Globoid

65. Helicon

66. Idragin

67. Levius

68. Pirseal

69. Rhonal

70. Solfrin

71. Adiro

72. Aspec

73. Aspro

74. Novid

75. Yasta

76. Acetosalic Acid

77. Triple-sal

78. Spira-dine

79. Zorprin

80. Bi-prin

81. Acetilum Acidulatum

82. Acimetten

83. Delgesic

84. Entrophen

85. Persistin

86. 2-carboxyphenyl Acetate

87. Acetilsalicilico

88. Dolean Ph 8

89. A.s.a. Empirin

90. Xaxa

91. Acido Acetilsalicilico

92. Contrheuma Retard

93. Acide Acetylsalicylique

94. Asa

95. Endosprin

96. Kapsazal

97. Bayer

98. Acetylsalicylsaure

99. Aspirin (acetylsalicylic Acid)

100. Solprin

101. Triaminicin

102. Asatard

103. Durlaza

104. Tasprin

105. Nu-seals Aspirin

106. Salicylic Acid, Acetate

107. Acido O-acetil-benzoico

108. Kyselina Acetylsalicylova

109. 2-acetoxybenzenecarboxylic Acid

110. St. Joseph Aspirin For Adults

111. A.s.a.

112. St. Joseph

113. Kyselina 2-acetoxybenzoova

114. Sp 189

115. Acetard

116. Ac 5230

117. Acetyl Salicylate

118. Acetylsalicylsaeure

119. Azetylsalizylsaeure

120. S-211

121. Ecm

122. Chebi:15365

123. 2-(acetyloxy)benzoate

124. Acetylsalicylicum Acidum

125. Nsc-27223

126. O-(acetyloxy)benzoic Acid

127. Nsc-406186

128. Acide 2-(acetyloxy)benzoique

129. Acetylsalicylic Acid (who-ip)

130. R16co5y76e

131. Aspirin Form Ii

132. Component Of Midol

133. Nsc27223

134. Component Of Synirin

135. 8-hour Bayer

136. Component Of Zactirin

137. Bay1019036

138. Component Of Coricidin

139. Component Of Persistin

140. Component Of Robaxisal

141. O-acetoxybenzoate

142. Ncgc00015067-04

143. Acetysal

144. Istopirin

145. Magnecyl

146. Medisyl

147. Polopirin

148. Ronal

149. Bayer Buffered

150. Dsstox_cid_108

151. Aspro Clear

152. Component Of Ascodeen-30

153. Bayer Plus

154. Wln: Qvr Bov1

155. Rheumin Tabletten

156. Acetylsalicylicacid

157. Dsstox_rid_75372

158. Dsstox_gsid_20108

159. Aspirina 03

160. Acetylsalycilic Acid

161. Acetyl Salicylic Acid

162. Component Of Darvon With A.s.a

163. Bayer Aspirin 8 Hour

164. Asaphen

165. Aspalon

166. Asprin

167. Bayer Children's Aspirin

168. Nu-seals

169. Component Of St. Joseph Cold Tablets

170. Aspir-mox

171. Durlaza Er

172. Acetylsalicylsaure [german]

173. Cas-50-78-2

174. Acetoxybenzoic Acid

175. Acetysalicylic Acid

176. 11126-35-5

177. Ain

178. Smr000059138

179. Ascoden-30

180. Benzoicacid, 2-(acetyloxy)-

181. Acetylsalicyclic Acid

182. Ccris 3243

183. Hsdb 652

184. Acide Acetylsalicylique [french]

185. Acido Acetilsalicilico [italian]

186. Kyselina Acetylsalicylova [czech]

187. Acido O-acetil-benzoico [italian]

188. Sr-01000075668

189. Kyselina 2-acetoxybenzoova [czech]

190. Bayer Extra Strength Aspirin For Migraine Pain

191. Einecs 200-064-1

192. Nsc 27223

193. Aspirin [usp:ban:jan]

194. Bayer Enteric 325 Mg Regular Strength

195. Brn 0779271

196. Bay E4465

197. Unii-r16co5y76e

198. Aspropharm

199. Bayer Enteric 81 Mg Adult Low Strength

200. Cardioaspirin

201. Cardioaspirina

202. Acetyonyl

203. Asacard

204. Ascolong

205. Bayer Enteric 500 Mg Arthritis Strength

206. Colsprin

207. Miniasal

208. Salospir

209. Acesan

210. Toldex

211. Ai3-02956

212. 1oxr

213. 2-acetoxybenzoate

214. Aspirin,(s)

215. Aspalon (jan)

216. Durlaza (tn)

217. Easprin (tn)

218. Mfcd00002430

219. Acetyl-salicylic Acid

220. Aspirin Usp-26

221. Acetyl Salicyclic Acid

222. O-(acetyloxy)benzoate

223. Percodan (salt/mix)

224. Ascriptin (salt/mix)

225. Micrainin (salt/mix)

226. 2-acetoxy Benzoic Acid

227. Spectrum_001245

228. 2-acetylsalicyclic Acid

229. Aspirin [vandf]

230. Aspirin [hsdb]

231. Salicylic Acid, Acetyl-

232. Aspirin [jan]

233. Aspirin [mi]

234. Chembl25

235. Aspirin [mart.]

236. Spectrum2_001899

237. Spectrum3_001295

238. Spectrum4_000099

239. Spectrum5_000740

240. Aspirin (jp17/usp)

241. Lopac-a-5376

242. Salycylacetylsalicylic Acid

243. Aspirin [usp-rs]

244. Benzoic Acid, 2-acetoxy-

245. Epitope Id:114151

246. Percodan Demi (salt/mix)

247. Soma Compound (salt/mix)

248. Zinc53

249. Ec 200-064-1

250. Acetylsalicylic Acid, 99%

251. Aspirin Usp (3080)

252. Cid_2244

253. Pravigard Pac (salt/mix)

254. Schembl1353

255. 2-(acetyloxy)-benzoic Acid

256. Aspirin Usp (2080b)

257. Bay-e-4465

258. Acetylsalicylic Acid-[13c]

259. Lopac0_000038

260. Kbiogr_000398

261. Kbiogr_002271

262. Kbioss_001725

263. Kbioss_002272

264. 4-10-00-00138 (beilstein Handbook Reference)

265. Mls001055329

266. Mls001066332

267. Mls001336045

268. Mls001336046

269. Aspirin [orange Book]

270. Bidd:gt0118

271. Divk1c_000555

272. Spectrum1500130

273. Spbio_001838

274. Acetylsalicylic Acid, >=99%

275. Axotal Component Aspirin

276. Azdone Component Aspirin

277. Codoxy Component Aspirin

278. Gtpl4139

279. (non-d)acetylsalicylic Acid-d3

280. Aspirin [usp Monograph]

281. O-acetylsalicylic Acid; Aspirin

282. Dtxsid5020108

283. Acetylsalicylic Acid-carboxy-14c

284. Aggrenox Component Aspirin

285. Bdbm22360

286. Duocover Component Aspirin

287. Excedrin Component Aspirin

288. Fiorinal Component Aspirin

289. Hms501l17

290. Kbio1_000555

291. Kbio2_001725

292. Kbio2_002271

293. Kbio2_004293

294. Kbio2_004839

295. Kbio2_006861

296. Kbio2_007407

297. Kbio3_002149

298. Kbio3_002751

299. Norgesic Component Aspirin

300. Percodan Component Aspirin

301. Q-gesic Component Aspirin

302. Roxiprin Component Aspirin

303. Vicoprin Component Aspirin

304. Yosprala Component Aspirin

305. Empirin With Codeine (salt/mix)

306. Acetylsalicylic Acid, >=99.0%

307. Cmap_000006

308. Component Of Zactirin (salt/mix)

309. Duoplavin Component Aspirin

310. Equagesic Component Aspirin

311. Invagesic Component Aspirin

312. Lanorinal Component Aspirin

313. Micrainin Component Aspirin

314. Ninds_000555

315. Robaxisal Component Aspirin

316. Aspirin Component Of Axotal

317. Aspirin Component Of Azdone

318. Aspirin Component Of Codoxy

319. Hms1920e13

320. Hms2090g03

321. Hms2091k13

322. Hms2233l18

323. Hms3260g17

324. Hms3372n15

325. Hms3656n14

326. Hms3715p19

327. Hms3866l03

328. Hms3885g03

329. Pharmakon1600-01500130

330. Acet