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Chemistry

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Also known as: Ws-12, Ws 12, (1r,2s,5r)-n-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide, Fema no. 4681, N-(4-methoxyphenyl)-p-menthanecarboxamide, Cyclohexanecarboxamide, n-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-, (1r,2s,5r)-
Molecular Formula
C18H27NO2
Molecular Weight
289.4  g/mol
InChI Key
HNSGVPAAXJJOPQ-XOKHGSTOSA-N
FDA UNII
1L7BVT4Z4Z

Acoltremon
Acoltremon is under investigation in clinical trial NCT05493111 (A Long-term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512).
1 2D Structure

Acoltremon

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide
2.1.2 InChI
InChI=1S/C18H27NO2/c1-12(2)16-10-5-13(3)11-17(16)18(20)19-14-6-8-15(21-4)9-7-14/h6-9,12-13,16-17H,5,10-11H2,1-4H3,(H,19,20)/t13-,16+,17-/m1/s1
2.1.3 InChI Key
HNSGVPAAXJJOPQ-XOKHGSTOSA-N
2.2 Other Identifiers
2.2.1 UNII
1L7BVT4Z4Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. N-(4-methoxyphenyl)-4-menthone-3-carboxamide

2. N-(4-methoxyphenyl)-p-menthone-3-carboxamide

3. Ws 12 Compound

4. Ws-12

5. Ws-12 Compound

6. Ws12 Compound

2.3.2 Depositor-Supplied Synonyms

1. Ws-12

2. Ws 12

3. (1r,2s,5r)-n-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide

4. Fema No. 4681

5. N-(4-methoxyphenyl)-p-menthanecarboxamide

6. Cyclohexanecarboxamide, N-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-, (1r,2s,5r)-

7. (1r,2s,5r)-n-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide

8. N-(4-methoxyphenyl)-p-menthane-carboxamide

9. (1r,2s,5r)-methoxyphenyl)-5-methyl-2-propan-n-(4-2-ylcyclohexane-1-carboxamide

10. N-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide, (1r,2s,5r)-

11. 68489-09-8

12. Acoltremon

13. Cyclohexanecarboxamide,n-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-, (1r,2s,5r)-

14. 1l7bvt4z4z

15. (1r,2s,5r)-n-(4-methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide

16. (1r,2s,5r)-2-isopropyl-n-(4-methoxyphenyl)-5-methylcyclohexane-1-carboxamide

17. Chembl2441929

18. Avx-012

19. [1r,2s,5r]-n-(4-methoxyphenyl)-p-menthanecarboxamide

20. Ws12

21. Hnsgvpaaxjjopq-xokhgstosa-n

22. Acoltremon [inn]

23. Unii-1l7bvt4z4z

24. Gtpl4343

25. Schembl2575067

26. Dtxsid10460636

27. Glxc-22261

28. Tca48909

29. Bdbm50442649

30. Akos024457397

31. Ws 12 Is Known As A Trpm8 Agonist.

32. Da-59157

33. Kxs

34. Hy-108449

35. Cs-0028711

36. E77039

37. Q27089230

38. N-(4-methoxyphenyl)-5-methyl-2- (1-methylethyl)cyclohexanecarboxamide, (1r,2s,5r)-

39. 847565-93-9

40. Cyclohexanecarboxamide, N-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-, [1r-(1alpha,2beta,5alpha)]-

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 289.4 g/mol
Molecular Formula C18H27NO2
XLogP34.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area38.3
Heavy Atom Count21
Formal Charge0
Complexity334
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 68489-09-8 / Acoltremon API manufacturers, exporters & distributors?

Acoltremon manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Acoltremon API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Acoltremon manufacturer or Acoltremon supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Acoltremon manufacturer or Acoltremon supplier.

PharmaCompass also assists you with knowing the Acoltremon API Price utilized in the formulation of products. Acoltremon API Price is not always fixed or binding as the Acoltremon Price is obtained through a variety of data sources. The Acoltremon Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Acoltremon

Synonyms

Ws-12, Ws 12, (1r,2s,5r)-n-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide, Fema no. 4681, N-(4-methoxyphenyl)-p-menthanecarboxamide, Cyclohexanecarboxamide, n-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-, (1r,2s,5r)-

Cas Number

68489-09-8

Unique Ingredient Identifier (UNII)

1L7BVT4Z4Z

About Acoltremon

Acoltremon is under investigation in clinical trial NCT05493111 (A Long-term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512).

Acoltremon Manufacturers

A Acoltremon manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Acoltremon, including repackagers and relabelers. The FDA regulates Acoltremon manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Acoltremon API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Acoltremon Suppliers

A Acoltremon supplier is an individual or a company that provides Acoltremon active pharmaceutical ingredient (API) or Acoltremon finished formulations upon request. The Acoltremon suppliers may include Acoltremon API manufacturers, exporters, distributors and traders.

Acoltremon GMP

Acoltremon Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Acoltremon GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Acoltremon GMP manufacturer or Acoltremon GMP API supplier for your needs.

Acoltremon CoA

A Acoltremon CoA (Certificate of Analysis) is a formal document that attests to Acoltremon's compliance with Acoltremon specifications and serves as a tool for batch-level quality control.

Acoltremon CoA mostly includes findings from lab analyses of a specific batch. For each Acoltremon CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Acoltremon may be tested according to a variety of international standards, such as European Pharmacopoeia (Acoltremon EP), Acoltremon JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Acoltremon USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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