Synopsis
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NDC API
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VMF
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EDQM
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USP
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JP
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Europe
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1. Cra 024781
2. Cra-024781
3. Cra024781
4. Pci 24781
5. Pci-24781
6. Pci24781
1. 783355-60-2
2. Pci-24781
3. Pci 24781
4. Cra-024781
5. Cra 024781
6. Cra-02478
7. Pci24781
8. Cra 24781
9. Abexinostat [usan]
10. 3-((dimethylamino)methyl)-n-(2-(4-(hydroxycarbamoyl)phenoxy)ethyl)benzofuran-2-carboxamide
11. Abexinostat (pci-24781)
12. Pci-24781 (abexinostat)
13. Pci-24781 (cra-024781)
14. S78454
15. Iyo470654u
16. Pzp115891
17. 3-((dimethylamino)methyl)-n-(2-(4-(hydroxycarbamoyl)-phenoxy)ethyl)benzofuran-2-carboxamide
18. Abexinostat (usan)
19. Pzp-115891
20. 3-(dimethylaminomethyl)-n-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide
21. 3-[(dimethylamino)methyl]-n-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide
22. S-78454
23. 3-[(dimethylamino)methyl]-n-[2-[4-[(hydroxyamino)carbonyl]phenoxy]ethyl]-2-benzofurancarboxamide
24. 3-[(dimethylamino)methyl]-n-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide
25. 2-benzofurancarboxamide, 3-((dimethylamino)methyl)-n-(2-(4-((hydroxyamino)carbonyl)phenoxy)ethyl)-
26. Abexinostat [usan:inn]
27. Unii-iyo470654u
28. 3-((dimethylamino)methyl)-n-(2-(4-(hydroxycarbamoyl)phenoxy)ethyl)-1-benzofuran-2-carboxamide
29. Cra024781
30. Abexinostat [inn]
31. Abexinostat(pci-24781)
32. Abexinostat [who-dd]
33. Mls006011097
34. Schembl444280
35. Gtpl8366
36. Chembl2103863
37. Bdbm24622
38. Chebi:92223
39. Dtxsid30229005
40. Bcpp000128
41. Hms3654a19
42. Ex-a2123
43. Zinc6716700
44. Cra-24781
45. Fd5037
46. Mfcd10565969
47. Nsc764136
48. Akos025149423
49. Bcp9001054
50. Ccg-264814
51. Cs-0478
52. Db12565
53. Nsc-764136
54. Sb16670
55. Ncgc00346486-01
56. Ncgc00346486-05
57. Ac-26866
58. Bs-18153
59. Hy-10990
60. Smr004702885
61. Db-075461
62. Pci-24781,cra-024781
63. Ft-0673532
64. Sw218266-2
65. Ec-000.2348
66. D10060
67. J-511438
68. Q4667249
69. Brd-k12867552-001-01-3
| Molecular Weight | 397.4 g/mol |
|---|---|
| Molecular Formula | C21H23N3O5 |
| XLogP3 | 2.2 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 8 |
| Exact Mass | 397.16377084 g/mol |
| Monoisotopic Mass | 397.16377084 g/mol |
| Topological Polar Surface Area | 104 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 550 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Histone Deacetylase Inhibitors
Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains. (See all compounds classified as Histone Deacetylase Inhibitors.)
Abexinostat is a novel histone deacetylase (HDAC) inhibitor. HDAC inhibitors target HDAC enzymes and inhibit the proliferation of cancer cells and induce cancer cell death, or apoptosis. Histone deacetylation is carried out by a family of related HDAC enzymes. Inhibition of these enzymes causes changes to chromatin structure and to gene expression patterns, which results in the inhibition of proliferation of cancer cells, and induction of apoptosis.
Drugs in Development
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PharmaCompass offers a list of Abexinostat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Abexinostat manufacturer or Abexinostat supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Abexinostat manufacturer or Abexinostat supplier.
PharmaCompass also assists you with knowing the Abexinostat API Price utilized in the formulation of products. Abexinostat API Price is not always fixed or binding as the Abexinostat Price is obtained through a variety of data sources. The Abexinostat Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Abexinostat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Abexinostat, including repackagers and relabelers. The FDA regulates Abexinostat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Abexinostat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Abexinostat supplier is an individual or a company that provides Abexinostat active pharmaceutical ingredient (API) or Abexinostat finished formulations upon request. The Abexinostat suppliers may include Abexinostat API manufacturers, exporters, distributors and traders.
Abexinostat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Abexinostat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Abexinostat GMP manufacturer or Abexinostat GMP API supplier for your needs.
A Abexinostat CoA (Certificate of Analysis) is a formal document that attests to Abexinostat's compliance with Abexinostat specifications and serves as a tool for batch-level quality control.
Abexinostat CoA mostly includes findings from lab analyses of a specific batch. For each Abexinostat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Abexinostat may be tested according to a variety of international standards, such as European Pharmacopoeia (Abexinostat EP), Abexinostat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Abexinostat USP).
