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Find Clinical Drug Pipeline Developments & Deals by Zydus Lifesciences
Roflumilast and its active metabolite (roflumilast N-oxide) are selective inhibitors of phosphodiesterase 4 (PDE4), which reduces inflammation in the lungs that leads to chronic obstructive pulmonary
disease (COPD).
Estradiol transdermal system is indicated for prevention of postmenopausal osteoporosis, it has the ability to reduce the elevated levels of these hormones seen in postmenopausal women.
Tavaborole topical solution is indicated to treat fungal toenail infections, it inhibits fungal protein synthesis by inhibition of an aminoacyl-transfer ribonucleic acid (tRNA) synthetase (AARS).
Azithromycin has antibacterial action as it binds to the 23S rRNA of the 50S ribosomal subunit of susceptible microorganisms inhibiting bacterial protein synthesis and impeding the assembly of the 50S ribosomal subunit.
Acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion (eg, some types of glaucoma), in the treatment of certain convulsive disorders and in the promotion of diuresis in instances of abnormal fluid retention.
Carbidopa and levodopa targets dopamine receptor, it is being approved for the treatment of motor fluctuations in patients with advanced parkinson's disease.
Levothyroxine sodium is a medicine used to treat an underactive thyroid gland (hypothyroidism). The thyroid gland makes thyroid hormones which help to control energy levels and growth. Levothyroxine is taken to replace the missing thyroid hormone thyroxine.
Doxepin hydrochloride is a psychotropic agent with antidepressant and anxiolytic properties as it binds with high affinity antagonist of histamine H1 receptor and exerts its sleep maintenance effect.
Loperamide hydrochloride binds to the opiate receptor in the gut wall and acts by slowing intestinal motility and by affecting water and electrolyte movement through the bowel.
Lubiprostone is a locally acting chloride channel activator that enhances a chloride-rich intestinal fluid secretion without altering sodium and potassium concentrations in the serum. It is indicated for chronic idiopathic constipation and IBS with constipation.
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