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    [{"orgOrder":0,"company":"Nexus Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Tirofiban","moa":"||Integrin-alpha-2b\/beta-3","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Nexus Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Nexus Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Nexus Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Second Affiliated Hospital, Guangxi Medical University","sponsor":"CSPC Pharmaceutical Group","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"","productType":"Enzyme","year":"2022","type":"Inapplicable","leadProduct":"Tenecteplase","moa":"||Tissue-type plasminogen activator","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase IV","graph3":"Second Affiliated Hospital, Guangxi Medical University","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Second Affiliated Hospital, Guangxi Medical University \/ CSPC Pharmaceutical Group","highestDevelopmentStatusID":"11","companyTruncated":"Second Affiliated Hospital, Guangxi Medical University \/ CSPC Pharmaceutical Group"},{"orgOrder":0,"company":"Medicure","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Tirofiban","moa":"||Integrin-alpha-2b\/beta-3","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase IV","graph3":"Medicure","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Medicure \/ Inapplicable","highestDevelopmentStatusID":"11","companyTruncated":"Medicure \/ Inapplicable"},{"orgOrder":0,"company":"Grand Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tirofiban","moa":"||Integrin alpha-IIb\/beta-3","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase II","graph3":"Grand Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Grand Pharma \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Grand Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Medicure","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Tirofiban","moa":"||Integrin-alpha-2b\/beta-3","graph1":"Hematology","graph2":"Phase II","graph3":"Medicure","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Medicure \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Medicure \/ Inapplicable"},{"orgOrder":0,"company":"Correvio Pharma","sponsor":"Hong Kong Teson Pharma","pharmaFlowCategory":"D","therapeuticArea":"Hematology","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Agreement","leadProduct":"Tirofiban","moa":"||Integrin-alpha-2b\/beta-3","graph1":"Hematology","graph2":"Approved FDF","graph3":"Correvio Pharma","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Correvio Pharma \/ Hong Kong Teson Pharma","highestDevelopmentStatusID":"15","companyTruncated":"Correvio Pharma \/ Hong Kong Teson Pharma"}]

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    Tirofiban Hydrochloride

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                            01

                            Nexus Pharmaceuticals

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                            Nexus Pharmaceuticals

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                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nexus Pharmaceuticals Inc. Receives FDA Approval for Tirofiban Hydrochloride Injection

                            Details : Tirofiban hydrochloride is a reversible antagonist of fibrinogen binding to the GP IIb/IIIa receptor. It is indicated to reduce the rate of thrombotic cardiovascular events in patients with non-ST elevation acute coronary syndrome.

                            Product Name : Tirofiban Hydrochloride-Generic

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 02, 2023

                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Second Affiliated Hospital, Guangxi Medical University

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                            EPSC
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                            Second Affiliated Hospital, Guangxi Medical University

                            Country arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Tenecteplase,Tirofiban

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase IV

                            Sponsor : CSPC Pharmaceutical Group

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Early Administration of Tirofiban in Patients Treated With Tenecteplase for Acute Ischemic Stroke

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            November 03, 2022

                            Lead Product(s) : Tenecteplase,Tirofiban

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase IV

                            Sponsor : CSPC Pharmaceutical Group

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Grand Pharma

                            China arrow
                            EPSC
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                            Grand Pharma

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                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study Evaluating the Safety and Efficacy of Tirofiban in Combination With Alteplase in Acute Ischemic Stroke

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 12, 2022

                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Correvio Pharma

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                            EPSC
                            Not Confirmed

                            Correvio Pharma

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                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Hematology

                            Study Phase : Approved FDF

                            Sponsor : Hong Kong Teson Pharma

                            Deal Size : $3.5 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Correvio Partners with Hong Kong Teson Pharma Limited

                            Details : The investment vehicle, which LSP claims is the largest of its type in Europe, is bigger than the VC shop’s three previous life science funds combined.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : $3.0 million

                            October 03, 2020

                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved FDF

                            Sponsor : Hong Kong Teson Pharma

                            Deal Size : $3.5 million

                            Deal Type : Agreement

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                            05

                            Medicure

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                            EPSC
                            Not Confirmed

                            Medicure

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                            EPSC
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                            Lead Product(s) : Tirofiban,Aspirin,Clopidogrel

                            Therapeutic Area : Hematology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Medicure Announces AGGRASTAT® Shows Promise in Treating Thrombotic Complications Due to COVID-19 in Early Cli...

                            Details : Notably, a non-randomized, case-controlled, investigator sponsored proof of concept study evaluating AGGRASTAT® in combination with standard of care in patients with severe COVID-19 and hypercoagulability found that enhanced platelet inhibition improves...

                            Product Name : Aggrastat

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 24, 2020

                            Lead Product(s) : Tirofiban,Aspirin,Clopidogrel

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Medicure

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                            EPSC
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                            Medicure

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                            EPSC
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                            Lead Product(s) : Tirofiban,Prasugrel

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Medicure Announces Top Line Data from FABOLUS-FASTER Trial With AGGRASTAT

                            Details : The FABOLUS-FASTER trial was designed to assess different regimens of intravenous platelet inhibitors, notably AGGRASTAT® (tirofiban hydrochloride) injection (an IV GP IIb/IIIa inhibitor) and cangrelor (an IV P2Y12 inhibitor) in the early phase of prima...

                            Product Name : Aggrastat

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 15, 2020

                            Lead Product(s) : Tirofiban,Prasugrel

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Medicure

                            Canada arrow
                            EPSC
                            Not Confirmed

                            Medicure

                            Canada arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Nephrology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pharmacokinetic Evaluation of Tirofiban Using a Single High-Dose Bolus In Subjects With Varying Degrees of Ren...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 11, 2013

                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Prince Sultan Cardiac Center, Adult Cardiology Department.

                            Country arrow
                            EPSC
                            Not Confirmed

                            Prince Sultan Cardiac Center, Adult Cardiology Department.

                            Country arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Tirofiban,Clopidogrel,Prasugrel

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The Effect Of Antiplatelets Therapy On Saphenous Vein Coronary Artery Bypass Graft Patency

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 15, 2012

                            Lead Product(s) : Tirofiban,Clopidogrel,Prasugrel

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Medicure

                            Canada arrow
                            EPSC
                            Not Confirmed

                            Medicure

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                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : SCRI Development Innovations, LLC

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 31, 2012

                            Lead Product(s) : Tirofiban,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : SCRI Development Innovations, LLC

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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