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Diagnosis","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"4","companyTruncated":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis"},{"orgOrder":0,"company":"The Division of Cancer Treatment and Diagnosis","sponsor":"Qualigen Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"F3-8-60","moa":"RAS","graph1":"Oncology","graph2":"Preclinical","graph3":"The Division of Cancer Treatment and Diagnosis","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"4","companyTruncated":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis"},{"orgOrder":0,"company":"The Division of Cancer Treatment and Diagnosis","sponsor":"Synergys Biotherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2022","type":"Funding","leadProduct":"SYN-001","moa":"Vasculogenic","graph1":"Oncology","graph2":"Preclinical","graph3":"The Division of Cancer Treatment and Diagnosis","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"4","companyTruncated":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis"},{"orgOrder":0,"company":"The Division of Cancer Treatment and Diagnosis","sponsor":"The Division of Cancer Treatment and Diagnosis","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Other Small Molecule","year":"2020","type":"Funding","leadProduct":"ART26.12","moa":"FABP5","graph1":"Oncology","graph2":"Discovery","graph3":"The Division of Cancer Treatment and Diagnosis","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"2","companyTruncated":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis"},{"orgOrder":0,"company":"The Division of Cancer Treatment and Diagnosis","sponsor":"BlueSphere Bio","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Discovery","graph3":"The Division of Cancer Treatment and Diagnosis","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"2","companyTruncated":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis"},{"orgOrder":0,"company":"The Division of Cancer Treatment and Diagnosis","sponsor":"Zenith Epigenetics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Agreement","leadProduct":"Ipilimumab","moa":"||BET","graph1":"Oncology","graph2":"Undisclosed","graph3":"The Division of Cancer Treatment and Diagnosis","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"1","companyTruncated":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis"},{"orgOrder":0,"company":"The Division of Cancer Treatment and Diagnosis","sponsor":"The Division of Cancer Treatment and Diagnosis","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Undisclosed","year":"2022","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Undisclosed","graph3":"The Division of Cancer Treatment and Diagnosis","amount2":0.01,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"1","companyTruncated":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis"},{"orgOrder":0,"company":"The Division of Cancer Treatment and Diagnosis","sponsor":"Weill Cornell Medicine","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Funding","leadProduct":"9-Valent HPV Vaccine Recombinant","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed","graph3":"The Division of Cancer Treatment and Diagnosis","amount2":0.01,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"1","companyTruncated":"The Division of Cancer Treatment and Diagnosis \/ The Division of Cancer Treatment and Diagnosis"}]

Find Clinical Drug Pipeline Developments & Deals by The Division of Cancer Treatment and Diagnosis

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The agreement aims to advance the development of camonsertib, a potential best-in-class oral small molecule ATR inhibitor, currently in Phase 1/2 in patients with ATM-altered tumors.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 11, 2024

                          Lead Product(s) : Camonsertib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Repare Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The collaboration aims for Biosplice to expand its clinical candidate, SM08502 (cirtuvivint), as a standalone treatment and combination therapy in patients with AML and MDS.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 09, 2024

                          Lead Product(s) : Cirtuvivint

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Biosplice

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The funding will be used to develop a new prodrug, CTT2274, that targets PSMA on prostate cancer and is designed to release a toxic drug, MMAE, within the cell that takes up the prodrug.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          November 18, 2024

                          Lead Product(s) : CTT2274

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Recipient : Cancer Targeted Technology

                          Deal Size : $2.4 million

                          Deal Type : Funding

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                          04

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : GMI-1271 (uproleselan) is a E-selectin inhibitor, which is being evaluated to treat adults with newly diagnosed acute myeloid leukemia (AML) who are 60 years or older.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 29, 2024

                          Lead Product(s) : Uproleselan,Etoposide,Mitoxantrone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Recipient : Crescent Biopharma

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The collaboration will seek to advance a novel TCR T-cell therapy, TCX-201, targeting recurrent respiratory papillomatosis (RRP), a rare orphan disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 06, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Recipient : BlueSphere Bio

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Under the agreement, the NCI and Aptose will collaborate on the clinical development of HM43239 (tuspetinib), an inhibitor of key signaling kinases involved in r/r acute myeloid leukemia.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          March 12, 2024

                          Lead Product(s) : Tuspetinib,Venetoclax

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Aptose Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          07

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : PRGN-2012 a new molecular entity, a HPV 6/11-specific T-cell response inducer, is an off the shelf OTS AdenoVerse gene therapy vaccine. It is in Phase I/II for recurrent respiratory papillomatosis.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          March 06, 2024

                          Lead Product(s) : Zopapogene Imadenovec

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Precigen

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The fundings will be used for the development of a unique bispecific antibody approach for treating Non-small Cell Lung Cancer (NSCLC), the most prevalent type of lung cancer in the United States.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 18, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : Traverse Biotech

                          Deal Size : Undisclosed

                          Deal Type : Funding

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                          09

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The agreement aims to advance development of the company’s differentiated anti-CTLA-4 antibody drug candidate for cancer treatment, GIGA-564, a fully human monoclonal antibody, distinguishes itself from currently available anti-CTLA-4 drugs.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          September 28, 2023

                          Lead Product(s) : GIGA-564

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Recipient : GigaGen

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          10

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The Company intends to use the funds for the development of Bria-OTS™, BriaCell’s novel personalized off-the-shelf immunotherapies for advanced metastatic breast cancer, prostate cancer, lung cancer, and melanoma.

                          Product Name : Bria-OTS

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          August 16, 2023

                          Lead Product(s) : Bria-OTS

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : BriaCell Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Funding

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