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Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Swedish Orphan Biovitrum AB \/ Inapplicable"},{"orgOrder":0,"company":"Swedish Orphan Biovitrum AB","sponsor":"Washington University School of Medicine","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Pacritinib","moa":"Tyrosine-protein kinase receptor FLT3 | Tyrosine-protein kinase JAK2","graph1":"Psychiatry\/Psychology","graph2":"Phase I","graph3":"Swedish Orphan Biovitrum AB","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Swedish Orphan Biovitrum AB \/ Swedish Orphan Biovitrum AB","highestDevelopmentStatusID":"6","companyTruncated":"Swedish Orphan Biovitrum AB \/ Swedish Orphan Biovitrum AB"},{"orgOrder":0,"company":"Swedish Orphan Biovitrum AB","sponsor":"Swedish Orphan Biovitrum AB","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"Anakinra","moa":"Interleukin-1 receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Swedish Orphan Biovitrum AB","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Swedish Orphan Biovitrum AB \/ Swedish Orphan Biovitrum AB","highestDevelopmentStatusID":"6","companyTruncated":"Swedish Orphan Biovitrum AB \/ Swedish Orphan Biovitrum AB"},{"orgOrder":0,"company":"Swedish Orphan Biovitrum AB","sponsor":"PSI CRO","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"SWEDEN","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Efanesoctocog Alfa","moa":"F8*","graph1":"Genetic Disease","graph2":"Phase IV","graph3":"Swedish Orphan Biovitrum AB","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Swedish Orphan Biovitrum AB \/ PSI CRO","highestDevelopmentStatusID":"11","companyTruncated":"Swedish Orphan Biovitrum AB \/ PSI CRO"},{"orgOrder":0,"company":"Swedish Orphan Biovitrum AB","sponsor":"PPD","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"SWEDEN","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"CYP450","moa":"Undisclosed","graph1":"Undisclosed","graph2":"Phase I","graph3":"Swedish Orphan Biovitrum AB","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Swedish Orphan Biovitrum AB \/ PPD","highestDevelopmentStatusID":"6","companyTruncated":"Swedish Orphan Biovitrum AB \/ PPD"}]

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                            01

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Approved FDF

                            Recipient : Apellis Pharmaceuticals

                            Deal Size : $300.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Sobi to amend existing agreement with Apellis for ex-U.S. royalties of Aspaveli

                            Details : Aspaveli (pegcetacoplan) is approved in the EU, other countries globally, and the US for the treatment of paroxysmal nocturnal haemoglobinuria (PNH) who have haemolytic anaemia, a rare blood disorder.

                            Product Name : Aspaveli

                            Product Type : Peptide

                            Upfront Cash : $275.0 million

                            July 01, 2025

                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Approved FDF

                            Recipient : Apellis Pharmaceuticals

                            Deal Size : $300.0 million

                            Deal Type : Agreement

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                            02

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Efanesoctocog Alfa

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase IV

                            Sponsor : PSI CRO

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Long-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world Prophylactic Treatme...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            April 23, 2025

                            Lead Product(s) : Efanesoctocog Alfa

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase IV

                            Sponsor : PSI CRO

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Apellis Gets FDA Priority Review for EMPAVELI in C3G & Primary IC-MPGN

                            Details : Aspaveli (pegcetacoplan) is the first and only approved therapy for geographic atrophy. Now it is being evaluated for the treatment of C3 glomerulopathy & IC-MPGN.

                            Product Name : Aspaveli

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            April 01, 2025

                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Olezarsen Sodium

                            Therapeutic Area : Genetic Disease

                            Study Phase : Approved FDF

                            Recipient : Ionis Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Ionis, Sobi Expand Partnership for Olezarsen Commercialization Outside U.S.

                            Details : Under the licensing agreement, Sobi will hold the exclusive rights in countries outside the U.S., Canada to commercialize Tryngolza (olezarsen sodium) as a potential treatment for FCS.

                            Product Name : Tryngolza

                            Product Type : Oligonucleotide

                            Upfront Cash : Undisclosed

                            March 26, 2025

                            Lead Product(s) : Olezarsen Sodium

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Approved FDF

                            Recipient : Ionis Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            05

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Emapalumab

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Grants Priority Review to Sobi's Gamifant sBLA

                            Details : Gamifant (emapalumab) is an anti-IFNγ monoclonal antibody that binds free and receptor-bound IFNγ, neutralizing its biological activity. Emapalumab is currently in Phase lll development for MAS.

                            Product Name : Gamifant

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 27, 2025

                            Lead Product(s) : Emapalumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Apellis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EMA Validates Aspaveli® for C3G and Primary IC-MPGN Treatment

                            Details : Aspaveli (pegcetacoplan) is the first and only approved therapy for geographic atrophy. Now it is being evaluated for the treatment of C3 glomerulopathy & IC-MPGN.

                            Product Name : Aspaveli

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            February 20, 2025

                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Apellis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Pacritinib

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase II

                            Sponsor : PSI CRO

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 17, 2025

                            Lead Product(s) : Pacritinib

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase II

                            Sponsor : PSI CRO

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Efanesoctocog Alfa

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase IV

                            Sponsor : PSI CRO

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Investigate the Course of Synovial Hypertrophy in Patients With Haemophilia A on Efanesoctocog Alfa...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            December 31, 2024

                            Lead Product(s) : Efanesoctocog Alfa

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase IV

                            Sponsor : PSI CRO

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Avatrombopag Maleate

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sobi's NDA for Avatrombopag To Treat Pediatric Immune Thrombocytopenia Accepted

                            Details : Doptelet (avatrombopag maleate), an oral thrombopoietin receptor agonist, which is indicated for the treatment of chronic immune thrombocytopenia in pediatric patients one year and older.

                            Product Name : Doptelet

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 12, 2024

                            Lead Product(s) : Avatrombopag Maleate

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Swedish Orphan Biovitrum AB

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                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Approved FDF

                            Recipient : Enable Injections

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Enable Injections Partners with Sobi To Develop Aspaveli® with enFuse®

                            Details : The agreement aims for the international development and distribution for the enFuse Injector, for the subcutaneous delivery of Aspaveli (pegcetacoplan), a targeted C3 therapy, for PNH.

                            Product Name : Aspaveli

                            Product Type : Peptide

                            Upfront Cash : Undisclosed

                            December 09, 2024

                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Approved FDF

                            Recipient : Enable Injections

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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