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    Find Clinical Drug Pipeline Developments & Deals by SiteOne Therapeutics

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                            01

                            SiteOne Therapeutics

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                            Lead Product(s) : STC-004

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Eli Lilly

                            Deal Size : $1,000.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Lilly to Expand its Pain Pipeline with Acquisition of SiteOne Therapeutics

                            Details : The acquisition of SiteOne Therapeutics includes STC-004, a next-generation, Phase 2 ready Nav1.8 inhibitor being studied as non-opioid treatment for patients suffering from chronic pain.

                            Product Name : STC-004

                            Product Type : Other Small Molecule

                            Upfront Cash : $1,000.0 million

                            May 27, 2025

                            Lead Product(s) : STC-004

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Eli Lilly

                            Deal Size : $1,000.0 million

                            Deal Type : Acquisition

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                            02

                            SiteOne Therapeutics

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                            Lead Product(s) : STC-004

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            SiteOne Reports Positive Phase 1 Data for STC-004, a NaV1.8 Pain Inhibitor

                            Details : STC-004 is an oral, highly selective NaV1.8 inhibitor under development for the treatment of acute and chronic peripheral pain.

                            Product Name : STC-004

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 04, 2025

                            Lead Product(s) : STC-004

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            SiteOne Therapeutics

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                            Lead Product(s) : STC-004

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Novo Holdings

                            Deal Size : $100.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            SiteOne Raises $100M Series C for Non-Opioid Pain Treatments Using Ion Modulators

                            Details : The financing will support the company in advancing its lead program, STC-004, a Nav1.8 blocker, which is being evaluated for the treatment of pain, cough, and other conditions.

                            Product Name : STC-004

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 18, 2024

                            Lead Product(s) : STC-004

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Novo Holdings

                            Deal Size : $100.0 million

                            Deal Type : Series C Financing

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                            04

                            SiteOne Therapeutics

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                            Lead Product(s) : STC-004

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : National Institute on Drug Abuse

                            Deal Size : $15.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            SiteOne Therapeutics Awarded up to $15M Grant to Develop NaV1.8 Inhibitor as Non-Opioid Therapeutic for Pain

                            Details : The funding will be used for the development of SiteOne's selective NaV1.8 inhibitor, STC-004, an investigational, non-opioid treatment for acute and chronic pain conditions.

                            Product Name : STC-004

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 18, 2023

                            Lead Product(s) : STC-004

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : National Institute on Drug Abuse

                            Deal Size : $15.0 million

                            Deal Type : Funding

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                            05

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                            Lead Product(s) : ST-2427

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            SiteOne Therapeutics Announces Collaboration and License Agreement with Vertex Pharmaceuticals to Advance NaV1...

                            Details : Under the terms of the agreement, the companies will work together to advance potent and selective inhibitors of sodium ion channel 1.7 (NaV1.7) as non-opioid therapeutics for the treatment of pain.

                            Product Name : ST-2427

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 19, 2022

                            Lead Product(s) : ST-2427

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            06

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Preclinical

                            Sponsor : National Institutes of Health

                            Deal Size : $1.7 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            SiteOne Therapeutics Announces $1.73M Grant from NIH/NHLBI and Adds Respiratory Advisory Team

                            Details : Funding will support the development of an inhaled formulation of SiteOne’s drug candidate for chronic cough through IND-enabling studies and toward the clinic.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            November 05, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Preclinical

                            Sponsor : National Institutes of Health

                            Deal Size : $1.7 million

                            Deal Type : Funding

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