Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : SION‑719
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Goldman Sachs & Co
Deal Size : $219.2 million
Deal Type : Public Offering
Sionna Announces Closing of $219.2 million Upsized Initial Public Offering
Details : The net proceeds from the offering will used to fund the clinical development of NBD1 products, including SION‑719, which is being evaluated for the treatement of Cystic fibrosis.
Product Name : SION‑719
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 10, 2025
Lead Product(s) : SION‑719
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Goldman Sachs & Co
Deal Size : $219.2 million
Deal Type : Public Offering
Lead Product(s) : SION‑719
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Goldman Sachs & Co
Deal Size : $191.0 million
Deal Type : Public Offering
Sionna Therapeutics Prices Upsized Initial Public Offering
Details : The net proceeds from the offering will used to fund the clinical development of NBD1 products, including SION‑719, which is being evaluated for the treatement of Cystic fibrosis.
Product Name : SION‑719
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 06, 2025
Lead Product(s) : SION‑719
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Goldman Sachs & Co
Deal Size : $191.0 million
Deal Type : Public Offering
Lead Product(s) : SION-638
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Enavate Sciences
Deal Size : $182.0 million
Deal Type : Series C Financing
Sionna Therapeutics Announces $182M Series C for Novel Cystic Fibrosis Molecules
Details : Proceeds will support clinical development of SION-638, a first-in-class small molecule designed to restore CFTR protein function by stabilizing the first nucleotide-binding domain.
Product Name : SION-638
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
June 03, 2024
Lead Product(s) : SION-638
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Enavate Sciences
Deal Size : $182.0 million
Deal Type : Series C Financing
Lead Product(s) : SION-109
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sionna Therapeutics Announces Phase 1 Initiation for SION-109 in Cystic Fibrosis
Details : SION-109 targets the interface between the ICL4 region and NBD1 of the CFTR protein, and is in phase 1 development for treating delta-F508 mutated Cystic Fibrosis.
Product Name : SION-109
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 24, 2024
Lead Product(s) : SION-109
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SION-638
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sionna Therapeutics Announces IND Clearance and Phase 1 Initiation for SION-638 in Cystic Fibrosis
Details : SION-638, a novel small molecule designed to target the first nucleotide-binding domain (NBD1) of the cystic fibrosis transmembrane conductance regulator (CFTR) protein.
Product Name : SION-638
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 12, 2022
Lead Product(s) : SION-638
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SION-638,Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : OrbiMed Advisors
Deal Size : $111.0 million
Deal Type : Series B Financing
Details : Sionna is advancing a pipeline of first-in-class small molecules, SION-638, designed to fully restore the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein that is defective in CF, by stabilizing CFTR's first nucleotide-b...
Product Name : SION-638
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 19, 2022
Lead Product(s) : SION-638,Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : OrbiMed Advisors
Deal Size : $111.0 million
Deal Type : Series B Financing