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    [{"orgOrder":0,"company":"Sino Biopharmaceutical","sponsor":"Sinovac Biotech","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"CHINA","productType":"Cell and Gene therapy","year":"2020","type":"Funding","leadProduct":"Inactivated Vero Cell","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Sino Biopharmaceutical","amount2":0.5,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.5,"dosageForm":"Intramuscular Injection","sponsorNew":"Sino Biopharmaceutical \/ Sino Biopharmaceutical","highestDevelopmentStatusID":"15","companyTruncated":"Sino Biopharmaceutical \/ Sino Biopharmaceutical"},{"orgOrder":0,"company":"Sino Biopharmaceutical","sponsor":"Akeso","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2021","type":"Inapplicable","leadProduct":"Penpulimab","moa":"Programmed cell death protein 1","graph1":"Oncology","graph2":"Approved FDF","graph3":"Sino Biopharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Sino Biopharmaceutical \/ Sino Biopharmaceutical","highestDevelopmentStatusID":"15","companyTruncated":"Sino Biopharmaceutical \/ Sino Biopharmaceutical"},{"orgOrder":0,"company":"Sino Biopharmaceutical","sponsor":"LaNova Medicines","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"HONG KONG","productType":"Antibody","year":"2025","type":"Acquisition","leadProduct":"LM-302","moa":"CLDN18.2","graph1":"Oncology","graph2":"Phase III","graph3":"Sino Biopharmaceutical","amount2":0.94999999999999996,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.94999999999999996,"dosageForm":"Intravenous Injection","sponsorNew":"Sino Biopharmaceutical \/ LaNova Medicines","highestDevelopmentStatusID":"10","companyTruncated":"Sino Biopharmaceutical \/ LaNova Medicines"},{"orgOrder":0,"company":"Sino Biopharmaceutical","sponsor":"Inventiva Pharma","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"FRANCE","productType":"Other Small Molecule","year":"2022","type":"Licensing Agreement","leadProduct":"Lanifibranor","moa":"Peroxisome proliferator-activated receptor","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase III","graph3":"Sino Biopharmaceutical","amount2":0.31,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hepatology","amount2New":0.31,"dosageForm":"Oral Tablet","sponsorNew":"Sino Biopharmaceutical \/ Sino Biopharmaceutical","highestDevelopmentStatusID":"10","companyTruncated":"Sino Biopharmaceutical \/ Sino Biopharmaceutical"},{"orgOrder":0,"company":"Sino Biopharmaceutical","sponsor":"Inventiva Pharma","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"FRANCE","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Lanifibranor","moa":"Peroxisome proliferator-activated receptor","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase III","graph3":"Sino Biopharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Sino Biopharmaceutical \/ Sino Biopharmaceutical","highestDevelopmentStatusID":"10","companyTruncated":"Sino Biopharmaceutical \/ Sino Biopharmaceutical"},{"orgOrder":0,"company":"Sino Biopharmaceutical","sponsor":"Treadwell Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Series B Financing","leadProduct":"CFI-400945","moa":"||Serine\/threonine-protein kinase PLK4","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Sino Biopharmaceutical","amount2":0.089999999999999997,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.089999999999999997,"dosageForm":"Oral Tablet","sponsorNew":"Sino Biopharmaceutical \/ Sino Biopharmaceutical","highestDevelopmentStatusID":"7","companyTruncated":"Sino Biopharmaceutical \/ Sino Biopharmaceutical"},{"orgOrder":0,"company":"Sino Biopharmaceutical","sponsor":"LaNova Medicines","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2024","type":"Series C Financing","leadProduct":"Apatinib","moa":"||CLDN18.2","graph1":"Oncology","graph2":"Phase III","graph3":"Sino Biopharmaceutical","amount2":0.040000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.040000000000000001,"dosageForm":"Undisclosed","sponsorNew":"Sino Biopharmaceutical \/ Sino Biopharmaceutical","highestDevelopmentStatusID":"10","companyTruncated":"Sino Biopharmaceutical \/ Sino Biopharmaceutical"}]

    Find Clinical Drug Pipeline Developments & Deals by Sino Biopharmaceutical

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                            01

                            Sino Biopharmaceutical

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                            Lead Product(s) : LM-302

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : LaNova Medicines

                            Deal Size : $951.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Sino Biopharmaceutical to Acquire LaNova Medicines for up to $951 million

                            Details : Upon completion of the acquisition, LaNova will become a wholly owned subsidiary of Sino. Its lead product, LM-302, is being evaluated for the treatment of CLDN18.2-positive gastric cancer.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            July 15, 2025

                            Lead Product(s) : LM-302

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : LaNova Medicines

                            Deal Size : $951.0 million

                            Deal Type : Acquisition

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                            02

                            Sino Biopharmaceutical

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                            Lead Product(s) : LM-302,Apatinib,Irinotecan Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : LaNova Medicines

                            Deal Size : $42.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            LaNova Initiates Phase 1 for LM-299 Anti-PD-1/VEGF Antibody and $42M Financing

                            Details : The financing is intended to support the clinical development of LM-302, an anti-CLDN 18.2 ADC, which is currently in late-stage clinical trials in China for the treatment of gastric cancers.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            October 18, 2024

                            Lead Product(s) : LM-302,Apatinib,Irinotecan Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : LaNova Medicines

                            Deal Size : $42.0 million

                            Deal Type : Series C Financing

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                            03

                            Sino Biopharmaceutical

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                            Lead Product(s) : Lanifibranor

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase III

                            Recipient : Inventiva Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inventiva Announces that its Partner Sino Biopharm Received IND Approval from the NMPA to initiate Clinical Tr...

                            Details : IVA337 (Lanifibranor), is an orally-available small molecule which induces anti-fibrotic, anti-inflammatory and beneficial vascular and metabolic changes in the body by activating all three PPAR isoforms, regulating gene expression.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 25, 2023

                            Lead Product(s) : Lanifibranor

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase III

                            Recipient : Inventiva Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Sino Biopharmaceutical

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                            Lead Product(s) : Lanifibranor

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase III

                            Recipient : Inventiva Pharma

                            Deal Size : $307.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Inventiva and Sino Biopharm Announce Licensing and Collaboration Agreement to Develop and Commercialize Lanifi...

                            Details : Lanifibranor (IVA337), is an orally-available small molecule with breakthrough therapy designation from the U.S. Food and Drug Administration (FDA) following a positive Phase IIb trial in patients with non-alcoholic steatohepatitis (NASH).

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : $12.0 million

                            September 21, 2022

                            Lead Product(s) : Lanifibranor

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase III

                            Recipient : Inventiva Pharma

                            Deal Size : $307.0 million

                            Deal Type : Licensing Agreement

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                            05

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                            Lead Product(s) : CFI-400945,Azacitidine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Treadwell Therapeutics

                            Deal Size : $91.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Treadwell Therapeutics Announces The Closing of a $91 Million Series B Financing

                            Details : Proceeds will fund the continued clinical development of CFI-400945, CFI-402257 and CFI-402411, the preclinical development of the Biologics and Cell Therapy platform, as well as general corporate purposes.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            November 18, 2021

                            Lead Product(s) : CFI-400945,Azacitidine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Treadwell Therapeutics

                            Deal Size : $91.0 million

                            Deal Type : Series B Financing

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                            06

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                            Lead Product(s) : Penpulimab

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Recipient : Akeso

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Penpulimab Monoclonal Antibody (PD-1) Obtains Marketing Approval in China

                            Details : Penpulimab is currently the only new PD-1 monoclonal antibody that applies IgG1 subtype and is modified by Fc segment, which has a lower antigen binding dissociation rate and a unique binding epitope as demonstrated by analysis on crystal structure.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 08, 2021

                            Lead Product(s) : Penpulimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Recipient : Akeso

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Sino Biopharmaceutical

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                            Lead Product(s) : Inactivated Vero Cell

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Recipient : Sinovac Biotech

                            Deal Size : $500.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Sinovac Secures Approximately $500 Million in Funding for COVID-19 Vaccine Development

                            Details : The investment deal comes as Sinovac expands supply deals and trials of its experimental COVID-19 vaccine CoronaVac with more countries following positive results from early to mid-stage clinical trials.

                            Product Name : CoronaVac

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 12, 2020

                            Lead Product(s) : Inactivated Vero Cell

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Recipient : Sinovac Biotech

                            Deal Size : $500.0 million

                            Deal Type : Funding

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