
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

Ractigen’s RAG-01 Shows Early Complete Response in Phase 1 NMIBC Study
Details : RAG-01 stands as a pioneering saRNA candidate from Ractigen Therapeutics, engineered to target and activate the tumor suppressor gene p21, intended for non-muscle-invasive bladder cancer.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
March 24, 2025

Ractigen Therapeutics Announces First Patient Dosed in Phase I Trial for RAG-17
Details : RAG-17 is a small interfering RNA (siRNA) targeting the Superoxide Dismutase 1 (SOD1) gene in the treatment of amyotrophic lateral sclerosis (ALS) associated with SOD1 mutations (ALS-SOD1).
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 24, 2024

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Lead Product(s) : RAG-21
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Ractigen Gains FDA Orphan Designation for RAG-21 in ALS Therapy Development
Details : RAG-21, its novel siRNA therapy targeting the FUS gene by reducing its level, for the treatment of FUS-amyotrophic lateral sclerosis
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 19, 2024
Lead Product(s) : RAG-21
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Ractigen Announces Positive Data For RAG-17 in ALS-SOD1 Treatment
Details : RAG-17 is a small interfering RNA (siRNA) targeting the Superoxide Dismutase 1 (SOD1) gene in the treatment of amyotrophic lateral sclerosis (ALS) associated with SOD1 mutations (ALS-SOD1).
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
September 10, 2024

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Lead Product(s) : RAG-18
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Ractigen Receives FDA Orphan Drug Designation for RAG-18 in DMD and BMD
Details : RAG-18 is a first of its kind saRNA candidate designed to specifically target and activate UTRN gene expression. It is being evaluated for duchenne muscular dystrophy & becker muscular dystrophy.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 22, 2024
Lead Product(s) : RAG-18
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Details : RAG-17 is a Oligonucleotide drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Amyotrophic Lateral Sclerosis.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
August 16, 2024

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Lead Product(s) : RAG-18
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Ractigen Receives FDA Pediatric Disease Designation for RAG-18 in Duchenne Dystrophy
Details : RAG-18 is a first of its kind saRNA candidate designed to specifically target and activate UTRN gene expression. It is being evaluated for duchenne muscular dystrophy & becker muscular dystrophy.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 25, 2024
Lead Product(s) : RAG-18
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Ractigen Secures FDA Fast Track Designation for RAG-01, a First-in-Class saRNA Therapy
Details : RAG-01 stands as a pioneering saRNA candidate from Ractigen Therapeutics, engineered to target and activate the tumor suppressor gene p21, intended for non-muscle-invasive bladder cancer.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
May 21, 2024

Ractigen Therapeutics Receives IND Approval for Phase 1 Trials of RAG-17 in ALS
Details : RAG-17 is a therapeutic siRNA specifically designed to suppress the SOD1 gene in Amyotrophic Lateral Sclerosis patients carrying the Superoxide Dismutase 1 (SOD1) mutation.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
May 15, 2024

Details : RAG-01 is a Oligonucleotide drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Urinary Bladder Neoplasms.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
April 08, 2024

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