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Find Drugs for Otolaryngology (Ear, Nose, Throat) in Phase II Clinical Development in FRANCE
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Details:
SENS-401 (R-azasetron besylate), is a 5-HT3 receptor antagonist and calcineurin inhibitor, orally available small molecule that aims to protect and preserve inner ear tissue from damage responsible of progressive or sequelae hearing impairment.
Lead Product(s):
R-Azasetron Besylate
Therapeutic Area: Otolaryngology (Ear, Nose, Throat)
Product Name: SENS-401
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
January 03, 2023
Details:
SENS-401 (Arazasetron) is a drug candidate that aims to protect and preserve inner ear tissue from damage that can cause progressive or sequelae hearing impairment.
Lead Product(s):
R-Azasetron Besylate
Therapeutic Area: Otolaryngology (Ear, Nose, Throat)
Product Name: SENS-401
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
September 14, 2022
Details:
Named AUDIBLE-S, the Phase II trial is being conducted to evaluate a 43.5mg and 29mg twice-daily dose of SENS-401 for four weeks in patients suffering from severe or profound SSNHL.
Lead Product(s):
Azasetron
Therapeutic Area: Otolaryngology (Ear, Nose, Throat)
Product Name: Undisclosed
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
February 18, 2020
Details:
The new centers will recruit volunteer military personnel exposed to impulse noise during their professional activities and suffering from hearing loss.
Lead Product(s):
Azasetron
Therapeutic Area: Otolaryngology (Ear, Nose, Throat)
Product Name: Undisclosed
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
February 17, 2020
Details:
SENS-401 significantly reduces ABR wave 1 amplitude loss after chronic noise exposure in a rat model.
Lead Product(s):
Azasetron
Therapeutic Area: Otolaryngology (Ear, Nose, Throat)
Product Name: Undisclosed
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
January 30, 2020