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                          Shanghai Chest Hospital

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                          Details : Osimertinib is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.

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                          July 10, 2025

                          Lead Product(s) : Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : AstraZeneca

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Orpathys (savolitinib) in combination with Tagrisso (osimertinib) is approved for the treatment of advanced or metastatic EGFR mutation-positive non-squamous non-small cell lung cancer.

                          Product Name : Orpathys

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 30, 2025

                          Lead Product(s) : Savolitinib,Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Tagrisso aka osimertinib is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC).

                          Product Name : Tagrisso

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 29, 2025

                          Lead Product(s) : Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : The DoD grant will help the company to advance it's early stage product ENV105 (carotuximab), which is being evaluated for NSCLC.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Undisclosed

                          April 17, 2025

                          Lead Product(s) : Carotuximab,Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : U S Department of Defense

                          Deal Size : $0.8 million

                          Deal Type : Funding

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                          05

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : under the agreement, LaunXP receives exclusive development and commercialization rights for APL-101 (vebreltinib) in combination with an EGFR inhibitor for the treatment of non-small cell lung cancer.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : $10.0 million

                          March 31, 2025

                          Lead Product(s) : Vebreltinib,Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : LaunXP Biomedical

                          Deal Size : $60.0 million

                          Deal Type : Agreement

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                          06

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : NXP900 is an oral SRC/YES1 kinase inhibitor is being investigated in combination with osimertinib (Tagrisso®) in EGFR-mutated non-small cell lung cancer (NSCLC) models.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 05, 2025

                          Lead Product(s) : NXP900,Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Orpathys is an MET tyrosine kinase inhibitor. Tagrisso is a third-generation, irreversible EGFR TKI. These are being evaluated in combination with EGFR mutation-positive non-small cell lung cancer.

                          Product Name : Orpathys

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 01, 2025

                          Lead Product(s) : Savolitinib,Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Orpathys (savolitinib) is an oral, potent and highly selective MET tyrosine kinase inhibitor. It is investigated in combination with osimertinib for EGFR-mutated NSCLC.

                          Product Name : Orpathys

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Savolitinib,Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Guangdong Association of Clinical Trials

                          Country arrow
                          OPRD
                          Not Confirmed

                          Guangdong Association of Clinical Trials

                          Country arrow
                          OPRD
                          Not Confirmed

                          Details : Osimertinib is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 29, 2024

                          Lead Product(s) : Osimertinib Mesylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Sponsor : Nanjing Geneseeq Technology Inc.

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Tagrisso (osimertinib) is being evaluated in the mid-stage clinical trial studies in combination with Orpathys (savolitinib) for EFGR-mutated non-small cell lung cancer.

                          Product Name : Tagrisso

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 16, 2024

                          Lead Product(s) : Osimertinib Mesylate,Savolitinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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