Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Povetacicept
Therapeutic Area : Nephrology
Study Phase : Phase III
Recipient : Vertex Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Ono and Vertex To Develop and Launch Povetacicept in Japan and South Korea
Details : Under the licensing agreement, Ono will utilize its expertise to help advance Vertex’s trials for ALPN-303 (povetacicept) and will be obtaining marketing authorizations in Japan and South Korea.
Product Name : ALPN-303
Product Type : Protein
Upfront Cash : Undisclosed
June 23, 2025
Lead Product(s) : Povetacicept
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Recipient : Vertex Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : SK Biopharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Cenobamate Demonstrates Clinical Efficacy and Safety across Korea, China and Japan
Details : Xcopri (cenobamate), is an antiseizure medication (ASM) for adults with partial-onset (focal) seizures, is now approved as oral suspension or can be administered via a nasogastric tube.
Product Name : Xcopri
Product Type : Controlled Substance
Upfront Cash : Inapplicable
December 10, 2024
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : SK Biopharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tirabrutinib Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ONO PHARMA Completes Enrollment for PROSPECT Study On Tirabrutinib
Details : ONO-4059 (tirabrutinib) is a highly selective irreversible Bruton's tyrosine kinase inhibitor. It is being evaluated for patients with relapsed or refractory primary central nervous system lymphoma.
Product Name : Velexbru
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 25, 2024
Lead Product(s) : Tirabrutinib Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tirabrutinib Hydrochloride
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Velexbru (tirabrutinib hydrochloride) is a highly selective, oral Bruton’s tyrosine kinase (BTK) inhibitor. It has received orphan drug designation from the FDA for the treatment of primary central nervous system lymphoma.
Product Name : Velexbru
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 22, 2023
Lead Product(s) : Tirabrutinib Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Nivolumab,Cisplatin,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Opdivo (nivolumab) is a PD-1 immune checkpoint inhibitor that is designed to uniquely harness the body’s own immune system to help restore anti-tumor immune response. It is been approved for treating resectable non-small cell lung cancer in Taiwan.
Product Name : Opdivo
Product Type : Antibody
Upfront Cash : Inapplicable
February 24, 2023
Lead Product(s) : Nivolumab,Cisplatin,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Encorafenib,Cetuximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In this study, BRAFTOVI and cetuximab combination treatment group demonstrated a statistically significant extension in overall survival (OS), versus the control group (irinotecan and cetuximab based combination treatment).
Product Name : Braftovi
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 20, 2021
Lead Product(s) : Encorafenib,Cetuximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Nivolumab,Ipilimumab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Bristol Myers Squibb
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Opdivo®, a human PD-1 monoclonal antibody, and Yervoy® Injection, a human monoclonal antibody against CTLA-4, in combination therapy for the first-line treatment of unresectable advanced or recurrent malignant pleural mesothelioma.
Product Name : Opdivo
Product Type : Antibody
Upfront Cash : Inapplicable
May 27, 2021
Lead Product(s) : Nivolumab,Ipilimumab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Bristol Myers Squibb
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : This application is based on the result from an investigator-initiated clinical study (NivoCUP study), conducted under the initiative of Kindai University Hospital, evaluating Opdivo in patients with cancer of unknown primary (CUP).
Product Name : Opdivo
Product Type : Antibody
Upfront Cash : Inapplicable
April 14, 2021
Lead Product(s) : Anamorelin HCl
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Marketing approval of Adlumiz® (generic name: anamorelin hydrochloride) Tablet 50mg (“Adlumiz”) is mainly based on the results from the ONO-7643-04 and ONO-7643-05 studies conducted in Japan in patients with cancer cachexia.
Product Name : Adlumiz
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 22, 2021
Lead Product(s) : Anamorelin HCl
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Etelcalcetide
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Parsabiv IV Injection Syringe Launched in Japan for Dialysis Patients
Details : Parsabiv (etelcalcetide HCl) is a calcium-sensing receptor agonist indicated for secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis.
Product Name : Parsabiv
Product Type : Peptide
Upfront Cash : Inapplicable
December 21, 2020
Lead Product(s) : Etelcalcetide
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable