Lead Product(s) : RVU120
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Ryvu Therapeutics
Deal Size : $1.0 million
Deal Type : Agreement
Details : RVU120 is a selective, first-in-class dual CDK8/CDK19 kinase inhibitor that has shown signs of clinical activity in treated patients, as well as efficacy in numerous in vitro and in vivo models of hematologic malignancies and solid tumors.
Product Name : RVU120
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
June 07, 2023
Lead Product(s) : RVU120
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Ryvu Therapeutics
Deal Size : $1.0 million
Deal Type : Agreement
Lead Product(s) : OAT-3912
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Ocean Biomedical
Deal Size : $32.6 million
Deal Type : Licensing Agreement
Ocean Biomedical Pens $32M Pact for Polish YKL-40 Inhibitors
Details : Under the agreement, Ocean Biomedical gains the exclusive rights to further research, develop, manufacture and commercialize Molecure’s OAT-3912 and other selective YKL-40 inhibitors worldwide.
Product Name : OAT-3912
Product Type : Other Large Molecule
Upfront Cash : $0.6 million
October 15, 2024
Lead Product(s) : OAT-3912
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Ocean Biomedical
Deal Size : $32.6 million
Deal Type : Licensing Agreement
Lead Product(s) : CT-01
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Compelling in-vitro and in-vivo preclinical data demonstrate that CT-01 candidate compounds induce degradation of Eukaryotic peptide chain release factor GTP-binding subunit, and another undisclosed neo-substrate with essential function in tumorigenesis.
Product Name : CT-01
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 04, 2022
Lead Product(s) : CT-01
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CPT-6281
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CPT-6281 as drug candidate for the CT-01 project, which will initially focus on the clinical development of the asset as a TPD treatment against hepatocellular carcinoma (HCC).
Product Name : CPT-6281
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 08, 2022
Lead Product(s) : CPT-6281
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CT-01
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Strong and comparable efficacy was demonstrated with CT-01 candidate, also confirming the potent antitumor activity in a liver cancer mouse xenograft model and no treatment-related toxicity was observed.
Product Name : CT-01
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 13, 2022
Lead Product(s) : CT-01
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Berubicin
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
WPD Pharma to Conduct Clinical Trials in Pediatric Brain Tumors
Details : The Company, in collaboration with CNS, is planning to conduct the upcoming Phase I clinical trial at Children's Memorial Health Institute
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 02, 2020
Lead Product(s) : Berubicin
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable