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SA","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"OSE Immunotherapeutics SA \/ Memorial Sloan Kettering Cancer Center","highestDevelopmentStatusID":"4","companyTruncated":"OSE Immunotherapeutics SA \/ Memorial Sloan Kettering Cancer Center"},{"orgOrder":0,"company":"Syndivia","sponsor":"GSK","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody-drug Conjugate","year":"2025","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Syndivia","amount2":0.34999999999999998,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.34999999999999998,"dosageForm":"Undisclosed","sponsorNew":"Syndivia \/ GSK","highestDevelopmentStatusID":"4","companyTruncated":"Syndivia \/ GSK"}]

Find Novel Oncology Drugs in Preclinical Development in FRANCE

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : K-NK004,Isatuximab

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Sanofi

                          Deal Size : $359.0 million

                          Deal Type : Acquisition

                          Details : Kiadis’ proprietary platform is based on allogeneic or ‘off-the-shelf' NK cells from a healthy donor. NK cells seek and identify malignant cancer cells and have broad application across various tumor types.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Undisclosed

                          November 02, 2020

                          Lead Product(s) : K-NK004,Isatuximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Sanofi

                          Deal Size : $359.0 million

                          Deal Type : Acquisition

                          Sanofi Company Banner

                          02

                          Lead Product(s) : K-NK003,Isatuximab

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The article describes the synergy of mbIL21 expanded NK cells (FC21-NK) modified with a CD38 gene knockout together with an anti-CD38 monoclonal antibody (mAb) for enhanced killing of multiple myeloma cells.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          July 22, 2020

                          Lead Product(s) : K-NK003,Isatuximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          03

                          Lead Product(s) : K-NK004,Isatuximab

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Sanofi

                          Deal Size : $986.0 million

                          Deal Type : Collaboration

                          Details : Combination of Kiadis’ CD38 knock out K-NK cells with Sanofi’s anti-CD38 antibody Sarclisa® enables optimal tumor cell killing, and offers a potential first-in-class treatment for patients with multiple myeloma.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : $20.4 million

                          July 08, 2020

                          Lead Product(s) : K-NK004,Isatuximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Sanofi

                          Deal Size : $986.0 million

                          Deal Type : Collaboration

                          Sanofi Company Banner

                          04

                          Lead Product(s) : K-NK002

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Poster presentation demonstrates similarity between K-NK cells produced with FC21 and PM21 and preclinical data with enhanced K-NK cell production and functionality using PM21.Fc.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          May 12, 2020

                          Lead Product(s) : K-NK002

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          05

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : Through the licensing deal, an undisclosed antibody-drug conjugate will be developed for prostate cancer treatment.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          October 27, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : GSK

                          Deal Size : $353.6 million

                          Deal Type : Licensing Agreement

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                          06

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : The Series A financing for ADCX-020, an unconjugated antibody targeting undisclosed cancer, aims to advance cancer therapeutics.

                          Product Name : ADCX-020

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Undisclosed

                          October 16, 2025

                          Lead Product(s) : ADCX-020

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Bpifrance

                          Deal Size : $122.0 million

                          Deal Type : Series A Financing

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                          07

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : The funding will help accelerate the industrialization of Allogenica’s lead-candidate CAR-T, called the XL-001 for treating CD19-positive blood cancers.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Undisclosed

                          March 19, 2025

                          Lead Product(s) : XL-001

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : French Government

                          Deal Size : $2.7 million

                          Deal Type : Funding

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                          08

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : Ipsen secures global rights to develop, manufacture and commercialize BMX-502, a pre-clinical bispecific antibody engaging MAIT cells, targeting GPC3 to kill cancer cells.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          December 02, 2024

                          Lead Product(s) : BMX-502

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Ipsen

                          Deal Size : $610.0 million

                          Deal Type : Licensing Agreement

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                          09

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : This new agreement is based on the initial multi-year research collaboration between MSK and OSE Immunotherapeutics to explore the preclinical potential against IL-7R Acute Lymphoblastic Leukemia.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 24, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Memorial Sloan Kettering Cancer Center

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          10

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : NUCLIDIUM and Guerbet will support the advancement of targeted copper-based radiotheranostics, 61Cu-based NuriPro, which binds specifically to PSMA, for the treatment of prostate cancer.

                          Product Name : NuriPro

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          May 22, 2024

                          Lead Product(s) : NuriPro

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : NUCLIDIUM

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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