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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : K-NK002

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Poster presentation demonstrates similarity between K-NK cells produced with FC21 and PM21 and preclinical data with enhanced K-NK cell production and functionality using PM21.Fc.

                          Product Name : K-NK002

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 05, 2020

                          Lead Product(s) : K-NK002

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          02

                          Lead Product(s) : K-NK003,Isatuximab

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The article describes the synergy of mbIL21 expanded NK cells (FC21-NK) modified with a CD38 gene knockout together with an anti-CD38 monoclonal antibody (mAb) for enhanced killing of multiple myeloma cells.

                          Product Name : K-NK003

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          July 22, 2020

                          Lead Product(s) : K-NK003,Isatuximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          03

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : The funding will help accelerate the industrialization of Allogenica’s lead-candidate CAR-T, called the XL-001 for treating CD19-positive blood cancers.

                          Product Name : XL-001

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          March 19, 2025

                          Lead Product(s) : XL-001

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : French Government

                          Deal Size : $2.7 million

                          Deal Type : Funding

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                          04

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : This new agreement is based on the initial multi-year research collaboration between MSK and OSE Immunotherapeutics to explore the preclinical potential against IL-7R Acute Lymphoblastic Leukemia.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 24, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Memorial Sloan Kettering Cancer Center

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : IPH45, a preclinical stage, novel and differentiated topoisomerase I inhibitor Antibody Drug Conjugate (ADC) targeting Nectin-4, which is being developed for tumors expressing Nectin-4.

                          Product Name : IPH45

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          June 03, 2024

                          Lead Product(s) : IPH45

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : NUCLIDIUM and Guerbet will support the advancement of targeted copper-based radiotheranostics, 61Cu-based NuriPro, which binds specifically to PSMA, for the treatment of prostate cancer.

                          Product Name : NuriPro

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          May 22, 2024

                          Lead Product(s) : NuriPro

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : NUCLIDIUM

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          07

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : DT-9045 is a novel protease-activated receptor 2 (PAR2) negative allosteric modulator, small molecule drug candidate. It is being evaluated for the treatment of cancer.

                          Product Name : DT-9045

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 26, 2024

                          Lead Product(s) : DT-9045

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Ipsen secures global rights to develop, manufacture and commercialize BMX-502, a pre-clinical bispecific antibody engaging MAIT cells, targeting GPC3 to kill cancer cells.

                          Product Name : BMX-502

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          February 12, 2024

                          Lead Product(s) : BMX-502

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Ipsen

                          Deal Size : $610.0 million

                          Deal Type : Licensing Agreement

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                          09

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : AQEMIA will use proceeds to enhance its small molecule drug discovery pipeline and scale its GenAI and deep physics drug discovery platform.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          January 30, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Wendel Growth

                          Deal Size : $64.5 million

                          Deal Type : Series A Financing

                          blank

                          10

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : A grant supports clinical progress of DT-7012, an anti-CCR8 monoclonal antibody, in preclinical studies for cutaneous T-cell lymphoma and other neoplasms.

                          Product Name : DT-7012

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          January 25, 2024

                          Lead Product(s) : DT-7012

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Agence Nationale de la Recherche

                          Deal Size : Undisclosed

                          Deal Type : Funding

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