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    [{"orgOrder":0,"company":"HaemaLogiX","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"HaemaLogiX","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"HaemaLogiX \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"HaemaLogiX \/ Inapplicable"},{"orgOrder":0,"company":"Starpharma","sponsor":"Merck & Co","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Undisclosed","year":"2021","type":"Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Starpharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Starpharma \/ Merck & Co","highestDevelopmentStatusID":"4","companyTruncated":"Starpharma \/ Merck & Co"},{"orgOrder":0,"company":"Cartherics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Cell and Gene therapy","year":"2024","type":"Private Placement","leadProduct":"CTH-401","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Cartherics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cartherics \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"Cartherics \/ Undisclosed"},{"orgOrder":0,"company":"Propanc Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Chymotrypsinogen","moa":"||Chymotrypsinogen","graph1":"Oncology","graph2":"Preclinical","graph3":"Propanc Biopharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Propanc Biopharma \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Propanc Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Propanc Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"Chymotrypsinogen","moa":"||Chymotrypsinogen","graph1":"Oncology","graph2":"Preclinical","graph3":"Propanc Biopharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Propanc Biopharma \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Propanc Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Radiopharm Theranostics","sponsor":"SHINE Technologies","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Other Small Molecule","year":"2022","type":"Agreement","leadProduct":"n.c.a. 177-Lu","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Radiopharm Theranostics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Radiopharm Theranostics \/ SHINE Technologies","highestDevelopmentStatusID":"4","companyTruncated":"Radiopharm Theranostics \/ SHINE Technologies"},{"orgOrder":0,"company":"Kazia Therapeutics","sponsor":"Vivesto","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Other Small Molecule","year":"2025","type":"Divestment","leadProduct":"Cantrixil","moa":"SMETI","graph1":"Oncology","graph2":"Preclinical","graph3":"Kazia Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kazia Therapeutics \/ Vivesto","highestDevelopmentStatusID":"4","companyTruncated":"Kazia Therapeutics \/ Vivesto"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            Kazia Therapeutics

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                            Lead Product(s) : Cantrixil

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Vivesto

                            Deal Size : $1.0 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Kazia Sells IP And Trademarks Rights For Cantrixil Asset

                            Details : Vivesto is currently exploring TRX-E-002-1 (cantrixil), a potent and selective third generation benzopyran SMETI inhibitor, preclinically for the treatment of hematological cancers.

                            Product Name : TRXE-002-01

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 31, 2025

                            Lead Product(s) : Cantrixil

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Vivesto

                            Deal Size : $1.0 million

                            Deal Type : Divestment

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                            02

                            Kazia Therapeutics

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                            Lead Product(s) : Paxalisib

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : QIMR Berghofer Medical Research Institute

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Kazia Executes Licensing Agreement with Qimr Berghofer

                            Details : Kazia receives an exclusive, worldwide, licence for the development of any drugs, including GDC-0084 (paxalisib) within the PI3K inhibitor class in combination with immunotherapy or PARP inhibitors.

                            Product Name : GDC-0084

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 09, 2024

                            Lead Product(s) : Paxalisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : QIMR Berghofer Medical Research Institute

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            03

                            Cartherics

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                            Cartherics

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                            Lead Product(s) : CTH-401

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : $15.0 million

                            Deal Type : Private Placement

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                            Cartherics Raises $15M To Advance Cell Therapy Programs

                            Details : The funding will support the clinical trial for CTH-401, the Company’s lead cell therapy and the only natural killer (NK) cell product currently under development for ovarian cancer.

                            Product Name : CTH-401

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 30, 2024

                            Lead Product(s) : CTH-401

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : $15.0 million

                            Deal Type : Private Placement

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                            04

                            Propanc Biopharma

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                            Propanc Biopharma

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                            Lead Product(s) : Chymotrypsinogen,Trypsinogen

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Propanc Biopharma Hosts Corporate Update Call on Recent Progress and Positive Results

                            Details : PRP is a mixture of two proenzymes, trypsinogen and chymotrypsinogen from bovine pancreas, administered by intravenous injection. A synergistic ratio of 1:6 inhibits growth of most tumor cells.

                            Product Name : PRP

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            February 22, 2024

                            Lead Product(s) : Chymotrypsinogen,Trypsinogen

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Propanc Biopharma

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                            Propanc Biopharma

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                            Lead Product(s) : Chymotrypsinogen,Trypsinogen

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Propanc Biopharma Targets Site of First-In-Human Study for PRP at the Peter Mac Cancer Center, Melbourne, Aust...

                            Details : PRP is a mixture of two proenzymes, trypsinogen and chymotrypsinogen from bovine pancreas, administered by intravenous injection. A synergistic ratio of 1:6 inhibits growth of most tumor cells.

                            Product Name : PRP

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            August 15, 2023

                            Lead Product(s) : Chymotrypsinogen,Trypsinogen

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            FivepHusion

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                            FivepHusion

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                            Lead Product(s) : Fluorouracil,Calcium Folinate,Oxaliplatin

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Allarity Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Allarity Therapeutics and FivepHusion Announce Collaboration to Support Clinical Development of Deflexifol™ ...

                            Details : Under the Agreement, Allarity will support FivepHusion’s future clinical development of Deflexifol (5-fluorouracil) for the treatment of solid tumors by using certain of Allarity’s drug-specific DRP® companion diagnostics, including its validated DR...

                            Product Name : Deflexifol

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Undisclosed

                            July 31, 2023

                            Lead Product(s) : Fluorouracil,Calcium Folinate,Oxaliplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Allarity Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Propanc Biopharma

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                            Propanc Biopharma

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                            Lead Product(s) : Chymotrypsinogen,Trypsinogen

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Peter MacCallum Cancer Centre

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Propanc Biopharma Announces Strategic Pharma Partnering Initiative

                            Details : The partnership aims for Propanc's lead product candidate, PRP (pancreatic proenzyme), a mixture of two proenzymes, trypsinogen and chymotrypsinogen, advancing towards a Phase I, first-in-human study in advanced cancer patients.

                            Product Name : PRP

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            June 06, 2023

                            Lead Product(s) : Chymotrypsinogen,Trypsinogen

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Peter MacCallum Cancer Centre

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            08

                            Amplia Therapeutics

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                            Amplia Therapeutics

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                            Lead Product(s) : AMP945,Fluorouracil,Calcium Folinate

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            AMP945 Combined with FOLFIRINOX Enhances Treatment Effects in Model of Pancreatic Cancer

                            Details : AMP945 (narmafotinib) is an orally bioavailable small molecule with a best-in-class profile. Amplia’s highly selective FAK inhibitor AMP945, when used in combination with FOLFIRINOX, enhances survival in a preclinical model of pancreatic cancer.

                            Product Name : AMP945

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 29, 2023

                            Lead Product(s) : AMP945,Fluorouracil,Calcium Folinate

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            HaemaLogiX

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                            HaemaLogiX

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            HaemaLogiX To Present Final Data from Anti-KMA CAR-T Preclinical Studies At AACR

                            Details : Anti-KMA CAR-T is a myeloma-specific antigen not found on normal cells. It has completed preclinical studies and is being developed to treat kappa-type multiple myeloma.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 27, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Radiopharm Theranostics

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                            Radiopharm Theranostics

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                            Lead Product(s) : n.c.a. 177-Lu

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : SHINE Technologies

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Radiopharm Theranostics and SHINE Technologies Announce Clinical Supply Agreement for Cancer-Fighting Medical ...

                            Details : The isotope will be used by Radiopharm in the development of its clinical pipeline of diagnostic and therapeutic radiopharmaceutical products including RAD206. Lu-177 is an important isotope utilized in multiple programs across Radiopharm’s portfolio.

                            Product Name : RAD206

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            September 19, 2022

                            Lead Product(s) : n.c.a. 177-Lu

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : SHINE Technologies

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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