Details:
Merck has decided to discontinue the phase II INTR@PID BTC 055 study evaluating bintrafusp alfa with gemcitabine + cisplatin in patients with locally advanced or metastatic biliary tract cancer, as the study is unlikely to achieve the primary objective of overall survival.
Lead Product(s): Bintrafusp Alfa,Gemcitabine,Cisplatin
Therapeutic Area: Oncology Product Name: M7824
Highest Development Status: Phase II/ Phase III Product Type: Large molecule
Partner/Sponsor/Collaborator: GSK
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable August 23, 2021
Details:
In the study of 159 patients, bintrafusp alfa demonstrated single-agent efficacy and durability with a manageable safety profile after more than nine months of follow-up, with an Independent Review Committee (IRC)-adjudicated objective response rate of 10.1% per RECIST 1.1.
Lead Product(s): Bintrafusp Alfa,Gemcitabine,Cisplatin
Therapeutic Area: Oncology Product Name: M7824
Highest Development Status: Phase II/ Phase III Product Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 16, 2021
Details:
MorphoSys and Incyte will co-commercialize tafasitamab in the U.S., while Incyte has exclusive commercialization rights outside of the U.S.
Lead Product(s): Tafasitamab
Therapeutic Area: Oncology Product Name: Undisclosed
Highest Development Status: Phase II/ Phase III Product Type: Large molecule
Partner/Sponsor/Collaborator: Incyte Corporation
Deal Size: $2,000.0 million Upfront Cash: $750.0 million
Deal Type: Collaboration January 13, 2020