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Bio \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Opna Bio \/ Inapplicable"},{"orgOrder":0,"company":"Debiopharm","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Debio 0123","moa":"||WEE1","graph1":"Oncology","graph2":"Phase I","graph3":"Debiopharm","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Debiopharm \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Debiopharm \/ Inapplicable"},{"orgOrder":0,"company":"Debiopharm","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Peptide","year":"2020","type":"Inapplicable","leadProduct":"177-Lu Minigastrin","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Debiopharm","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Debiopharm \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Debiopharm \/ Inapplicable"},{"orgOrder":0,"company":"F. Hoffmann-La Roche","sponsor":"Vividion Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2025","type":"Licensing Agreement","leadProduct":"VVD-214","moa":"||WRN","graph1":"Oncology","graph2":"Phase I","graph3":"F. Hoffmann-La Roche","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"F. Hoffmann-La Roche \/ Vividion Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"F. Hoffmann-La Roche \/ Vividion Therapeutics"},{"orgOrder":0,"company":"Philochem","sponsor":"RayzeBio","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Radiolabelled Compounds","year":"2025","type":"Licensing Agreement","leadProduct":"68-Ga OncoACP3","moa":"ACP3","graph1":"Oncology","graph2":"Phase I","graph3":"Philochem","amount2":1.3500000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":1.3500000000000001,"dosageForm":"Intravenous Injection","sponsorNew":"Philochem \/ RayzeBio","highestDevelopmentStatusID":"6","companyTruncated":"Philochem \/ RayzeBio"}]

Find Oncology Drugs in Phase I Clinical Development in SWITZERLAND

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : Under the licensing agreement, RayzeBio will hold the rights to develop, manufacture, and commercialise 68-Ga OncoACP3, a clinical stage therapeutic and diagnostic agent targeting prostate cancer.

                          Product Name : 68-Ga OncoACP3

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : $350.0 million

                          June 10, 2025

                          Lead Product(s) : 68-Ga OncoACP3

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : RayzeBio

                          Deal Size : $1,350.0 million

                          Deal Type : Licensing Agreement

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                          02

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : Under the licensing agreement, Vividion secured exclusive worldwide rights to develop and commercialize the clinical-stage Werner helicase (WRN) covalent inhibitor VVD-214 (RO7589831).

                          Product Name : VVD-214

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          June 04, 2025

                          Lead Product(s) : VVD-214,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Vividion Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : OPN-6602 is a potent and selective EP300/CBP bromodomain inhibitor, which is currenty being evaluated for the treatment of relapsed or refractory multiple myeloma.

                          Product Name : OPN-6602

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 12, 2025

                          Lead Product(s) : OPN-6602,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : Zynlonta (loncastuximab tesirine) is a CD19-directed ADC, which is being evaluated in combination with glofitamab & obinutuzumab for the treatment of relapsed/refractory B-cell non-Hodgkin lymphoma.

                          Product Name : Zynlonta

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Loncastuximab Tesirine,Glofitamab,Obinutuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : OPN-2853, a small molecule bromodomain and extra-terminal motif (BET) inhibitor, is being evaluated in combination with for treating intermediate-2 or high risk myelofibrosis.

                          Product Name : OPN-2853

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 09, 2024

                          Lead Product(s) : OPN-2853,Ruxolitinib Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : NM32 is a next generation tri-specific immuno-oncology drug targeting the ROR1 receptor & CD3. It is being evaluated for the treatment of solid tumors.

                          Product Name : NM32

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          October 30, 2024

                          Lead Product(s) : NM32-2668

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : RO7617991 is a MAGEA4 inhibitor antibody candidate, being evaluated for treatment of patients with locally advanced or metastatic MAGE-A4-positive solid tumors.

                          Product Name : RO7617991

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          October 18, 2024

                          Lead Product(s) : RO7617991,Tocilizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : IOA-244 (roginolisib) is a first-in-class small molecule allosteric modulator of PI3Kδ. It is being evaluated for the treatment of non-small cell lung cancer.

                          Product Name : IOA-244

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 07, 2024

                          Lead Product(s) : Roginolisib,Dostarlimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : OPN-6602 is a potent and selective EP300/CBP bromodomain inhibitor, which is currenty being evaluated for the treatment of relapsed or refractory multiple myeloma.

                          Product Name : OPN-6602

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 26, 2024

                          Lead Product(s) : OPN-6602,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Discovery Europe
                          Not Confirmed
                          Discovery Europe
                          Not Confirmed

                          Details : Debio 0123, an oral, potent, highly selective, and brain-penetrant WEE1 inhibitor is being evaluated in Phase I clinical trial studies for patients with advanced solid tumors.

                          Product Name : Debio 0123

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 03, 2024

                          Lead Product(s) : Debio 0123

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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