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    [{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"PFL-002","moa":"c-Met receptor","graph1":"Oncology","graph2":"IND Enabling","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pierre Fabre \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Pierre Fabre \/ Inapplicable"},{"orgOrder":0,"company":"Transgene","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"Tipapkinogen sovacivec","moa":"||Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Transgene","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Transgene \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Transgene \/ Inapplicable"},{"orgOrder":0,"company":"AB Science","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"AB8939","moa":"Tubulin","graph1":"Oncology","graph2":"IND Enabling","graph3":"AB Science","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"AB Science \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"AB Science \/ Inapplicable"},{"orgOrder":0,"company":"AB Science","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"AB8939","moa":"Tubulin","graph1":"Oncology","graph2":"IND Enabling","graph3":"AB Science","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"AB Science \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"AB Science \/ Inapplicable"},{"orgOrder":0,"company":"Cellectis","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"UCART20x22","moa":"CD20\/22","graph1":"Oncology","graph2":"IND Enabling","graph3":"Cellectis","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cellectis \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Cellectis \/ Inapplicable"},{"orgOrder":0,"company":"Cellectis","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"UCART20x22","moa":"CD20\/22","graph1":"Oncology","graph2":"IND Enabling","graph3":"Cellectis","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cellectis \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Cellectis \/ Inapplicable"},{"orgOrder":0,"company":"HEPHAISTOS-Pharma","sponsor":"Xista Science Ventures","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Undisclosed","year":"2024","type":"Financing","leadProduct":"Onco-Boost","moa":"Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"HEPHAISTOS-Pharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"HEPHAISTOS-Pharma \/ Xista Science Ventures","highestDevelopmentStatusID":"5","companyTruncated":"HEPHAISTOS-Pharma \/ Xista Science Ventures"},{"orgOrder":0,"company":"Bio Elpida","sponsor":"Biovaxys","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"BVX-0918A","moa":"Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Bio Elpida","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Bio Elpida \/ Biovaxys","highestDevelopmentStatusID":"5","companyTruncated":"Bio Elpida \/ Biovaxys"},{"orgOrder":0,"company":"Bio Elpida","sponsor":"Biovaxys","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Vaccine","year":"2021","type":"Partnership","leadProduct":"BVX-0918A","moa":"Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Bio Elpida","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Bio Elpida \/ Biovaxys","highestDevelopmentStatusID":"5","companyTruncated":"Bio Elpida \/ Biovaxys"},{"orgOrder":0,"company":"Bio Elpida","sponsor":"Biovaxys","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Vaccine","year":"2021","type":"Agreement","leadProduct":"BVX-0918A","moa":"Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Bio Elpida","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Bio Elpida \/ Biovaxys","highestDevelopmentStatusID":"5","companyTruncated":"Bio Elpida \/ Biovaxys"},{"orgOrder":0,"company":"Roca Therapeutics","sponsor":"3B Future Health Fund II","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Small Molecule","year":"2022","type":"Financing","leadProduct":"RCT001","moa":"Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Roca Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Roca Therapeutics \/ 3B Future Health Fund II","highestDevelopmentStatusID":"5","companyTruncated":"Roca Therapeutics \/ 3B Future Health Fund II"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            Innate Pharma

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                            Specialty & Agro Chemical
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                            Innate Pharma

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                            Lead Product(s) : IPH4502

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Innate Pharma Receives FDA Clearance for IND of IPH4502 in Solid Tumors

                            Details : IPH4502 is Innate’s novel and differentiated topoisomerase I inhibitor antibody-drug conjugate (ADC) targeting Nectin-4 to treat neoplasms.

                            Product Name : IPH4502

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            September 23, 2024

                            Lead Product(s) : IPH4502

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Pierre Fabre

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed

                            Pierre Fabre

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                            Specialty & Agro Chemical
                            Not Confirmed
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                            Lead Product(s) : PFL-002

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pierre Fabre: IND for PFL-002/VERT-002 in Solid Tumors with MET Mutations

                            Details : PFL-002/VERT-002 is a mAb developed by Vertical Bio, acting as a degrader of c-MET, in patients with solid tumors, including non-small cell lung cancer with mutations or amplification of MET.

                            Product Name : VERT-002

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            May 06, 2024

                            Lead Product(s) : PFL-002

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            HEPHAISTOS-Pharma

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed

                            HEPHAISTOS-Pharma

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                            Specialty & Agro Chemical
                            Not Confirmed
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                            Lead Product(s) : Onco-Boost

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Xista Science Ventures

                            Deal Size : $2.1 million

                            Deal Type : Financing

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                            HEPHAISTOS-Pharma Raises €2 Million Seed Round with Xista Science Ventures and Others

                            Details : The proceeds will enable HEPHAISTOS to advance ONCO-Boost into clinical development for solid tumors, focusing on unmet needs like sarcoma.

                            Product Name : Onco-Boost

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 23, 2024

                            Lead Product(s) : Onco-Boost

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Xista Science Ventures

                            Deal Size : $2.1 million

                            Deal Type : Financing

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                            04

                            Transgene

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed

                            Transgene

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed
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                            Lead Product(s) : TG6050

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Transgene Receives Approval to Start a Phase I Trial of TG6050, a Novel IL-12-Armed Oncolytic Virus Given by I...

                            Details : TG6050 is an oncolytic virus developed with Transgene’s Invir.IO™ platform for intravenous administration. TG6050 has been engineered to encode human IL-12, a cytokine that triggers a powerful antitumor immune response and a full length antiCTLA4 ant...

                            Product Name : TG6050

                            Product Type : Microorganism

                            Upfront Cash : Inapplicable

                            June 01, 2023

                            Lead Product(s) : TG6050

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Invectys

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed

                            Invectys

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                            Specialty & Agro Chemical
                            Not Confirmed
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                            Lead Product(s) : IVS-3001

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : CTMC

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Updated Invectys and CTMC Announce FDA Clearance of IND Application for Anti-HLA-G CAR-T Cell Therapy

                            Details : IVS-3001, Invectys’s lead engineered human leukocyte antigen A (HLA-G) targeting chimeric antigen receptor (CAR) T cell therapy for the treatment of solid tumors.

                            Product Name : IVS-3001

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 20, 2022

                            Lead Product(s) : IVS-3001

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : CTMC

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Invectys

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                            Specialty & Agro Chemical
                            Not Confirmed

                            Invectys

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed
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                            Lead Product(s) : IVS-3001

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : CTMA

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Invectys and CTMC Announce FDA Clearance of IND Application for Anti-HLA-G CAR-T Cell Therapy

                            Details : IVS-3001 is an HLA-G-targeting chimeric antigen receptor (CAR) T cell therapy. HLA-G is not only an immune checkpoint but also a tumor-specific antigen. IVS-3001 preclinical studies have generated adequate data to support efficacy and safety of the CAR-T...

                            Product Name : IVS-3001

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 19, 2022

                            Lead Product(s) : IVS-3001

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : CTMA

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Roca Therapeutics

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                            Specialty & Agro Chemical
                            Not Confirmed

                            Roca Therapeutics

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                            Specialty & Agro Chemical
                            Not Confirmed
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                            Lead Product(s) : RCT001

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : 3B Future Health Fund II

                            Deal Size : Undisclosed

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Roca Therapeutics Completes Seed Funding Round

                            Details : Company will use funds to develop its lead candidate RCT001 (Metastatic Uveal Melanoma) until IND/CTA readiness in 2023, and to expand portfolio of assets with the nomination of a second clinical candidate against Neovascular Glaucoma associated to Uveal...

                            Product Name : RCT001

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            September 22, 2022

                            Lead Product(s) : RCT001

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : 3B Future Health Fund II

                            Deal Size : Undisclosed

                            Deal Type : Financing

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                            08

                            Bio Elpida

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                            Specialty & Agro Chemical
                            Not Confirmed

                            Bio Elpida

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                            Specialty & Agro Chemical
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                            Lead Product(s) : BVX-0918A

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Biovaxys

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bio-Manufacturing Partner BioElpida Completes Next Phase of BVX-0918 GMP Production for EU Clinical Study

                            Details : BVX-0918A, BioVaxys’s cancer vaccines are created by extracting a patient’s own cancer cells, chemically treating them with a hapten, and re-injecting them into the patient to induce an immune response to proteins which are otherwise not immunogenic.

                            Product Name : BVX-0918A

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            August 06, 2022

                            Lead Product(s) : BVX-0918A

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Biovaxys

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Transgene

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed

                            Transgene

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed
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                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Transgene Announces Positive Interim Analysis Results of Phase II Trial Evaluating TG4001 + Avelumab vs Avelum...

                            Details : TG4001 is a therapeutic cancer vaccine candidate using an attenuated and modified poxvirus (MVA) as a vector expressing the HPV16 E6 and E7 proteins (rendered non-oncogenic) interleukin-2.

                            Product Name : TG4001

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 11, 2022

                            Lead Product(s) : Tipapkinogen sovacivec,Avelumab

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Cellectis

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed

                            Cellectis

                            France arrow
                            Specialty & Agro Chemical
                            Not Confirmed
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                            Lead Product(s) : UCART20x22

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cellectis Receives IND clearance for UCART20x22, its First in-house Manufactured Product Candidate for the Tre...

                            Details : UCART20x22 is also our first product candidate with fully integrated in-house development, showcasing our transformation into an end-to-end cell and gene therapy company, from discovery, process development, and GMP manufacturing to clinical development.

                            Product Name : UCART20x22

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            January 08, 2022

                            Lead Product(s) : UCART20x22

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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