Drugs in Dev.
Oncology
IND Enabling
Australia 
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Lead Product(s) : Betabart
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Clears Radiopharm IND For Betabart (RV-01) Phase I Targeting B7H3
Details : RV-01 (betabart), its Lu177-B7H3 monoclonal antibody designed with strong affinity for the 4Ig isoform of B7H3 that is highly expressed in tumors and not in healthy tissues.
Product Name : RV-01
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
July 28, 2025
Lead Product(s) : Betabart
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 177-Lu BetaBart
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : The University of Texas MD Anderson Cancer Center
Deal Size : Inapplicable
Deal Type : Inapplicable
Radiopharm Shows Lu177-B7H3-mAb with Favourable Biodistribution, High Tumour Uptake
Details : RV01 is the Company’s B7-H3-targeted radiopharmaceutical therapy designed with strong affinity for the 4Ig isoform of B7H3.
Product Name : RV01
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
June 02, 2025
Lead Product(s) : 177-Lu BetaBart
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : The University of Texas MD Anderson Cancer Center
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 177-Lu RAD202
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RAD 202 Receives Approval to Start Phase 1 Therapeutic Trial
Details : 177Lu-RAD202 is an HER2 inhibitor, antibody radiopharmaceutical candiidate, which is being evaluated for the treatment of HER2-expressing solid tumors.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
December 20, 2024
Lead Product(s) : 177-Lu RAD202
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AMP945,Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Clearance of Amplia's IND for Pancreatic Cancer Trial in US
Details : AMP945 (narmafotinib) is a novel focal adhesion kinase (FAK) inhibitor. It is being evaluated in precliical studies for the treatment of patients with pancreatic cancer.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
January 17, 2024
Lead Product(s) : AMP945,Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : CHM 2101
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CHM 2101 is a 3rd generation, novel CDH17 CAR T cell therapy that targets CDH17, a cancer target associated with poor prognosis and metastasis in the most common gastrointestinal tumors including colorectal cancer, gastric cancer and neuroendocrine tumor...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
October 31, 2023
Lead Product(s) : CHM 2101
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : RAD204
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RAD Receives Approval for Phase 1 Therapeutic Study of PDL1-nanobody in Non-Small Cell Lung Cancer
Details : RAD204, which targets PDL1-positive NSCLC, which used technology underpinning the trial is Radiopharm’s proprietary nanobody from its NanoMab platform.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 09, 2023
Lead Product(s) : RAD204
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : CF33-CD19,Blinatumomab
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Clears Imugene IND To Commence onCARlytics First-In-Class Clinical Study
Details : onCARlytics (CF33-CD19, HOV4) is a live, attenuated oncolytic orthopox (vaccinia) virus engineered to encode a truncated human CD19 transgene, resulting in expression of de novo CD19 at the tumour cell surface before virus-mediated tumour cell lysis.
Product Name : onCARlytics
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 19, 2023
Lead Product(s) : CF33-CD19,Blinatumomab
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Eftilagimod Alpha,Avelumab
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Merck Group
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMP321 (eftilagimod alpha) is a soluble LAG-3 protein and MHC Class II agonist that stimulates both innate and adaptive immunity for the treatment of cancer. It is being investigated in combination with bavencio in metastatic urothelial cancer.
Product Name : Efti
Product Type : Protein
Upfront Cash : Inapplicable
May 01, 2023
Lead Product(s) : Eftilagimod Alpha,Avelumab
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Merck Group
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : CTH-004
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Shunxi Holding Group
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Cartherics Grants Shunxi Licence for CAR-T Cell Therapy for Ovarian Cancer in Greater China
Details : The agreement provides Shunxi a licence to develop, manufacture and commercialise CTH-004, for the treatment of multiple solid tumours including ovarian cancer in Greater China, as well as an option to negotiate rights to other CAR-T products that incorp...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
April 28, 2023
Lead Product(s) : CTH-004
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Shunxi Holding Group
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : CNA3103
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CNA3103 is a LGR5 targeted CAR-T cells have potential to be developed as a novel immunotherapy to kill ovarian cancer cells and to reduce ovarian cancer tumor.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
February 06, 2023
Lead Product(s) : CNA3103
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
