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    [{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"ISRAEL","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Injection","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2023","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"ISRAEL","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2023","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2023","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2023","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2025","type":"Inapplicable","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2024","type":"Private Placement","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Undisclosed"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Other Large Molecule","year":"2024","type":"Private Placement","leadProduct":"Exosome","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"IND Enabling","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"NurExone Biologic \/ Undisclosed"},{"orgOrder":0,"company":"NurExone 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Biologic","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NurExone Biologic \/ Israeli Shekels","highestDevelopmentStatusID":"4","companyTruncated":"NurExone Biologic \/ Israeli Shekels"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"ExoPTEN\u00a0","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Preclinical","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"ExoPTEN\u00a0","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Preclinical","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"ExoPTEN\u00a0","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Preclinical","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"ExoPTEN\u00a0","moa":"PTEN","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Preclinical","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Nasal","sponsorNew":"NurExone Biologic \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"NurExone Biologic \/ Inapplicable"},{"orgOrder":0,"company":"NurExone Biologic","sponsor":"Inteligex","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"ISRAEL","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Preclinical","graph3":"NurExone Biologic","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NurExone Biologic \/ Inteligex","highestDevelopmentStatusID":"4","companyTruncated":"NurExone Biologic \/ Inteligex"}]

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                            01

                            NurExone Biologic

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                            BIOHK2025
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                            NurExone Biologic

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                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ExoPTEN Study Shows Potential to Boost Motor Function, Blood Flow, SCI Recovery

                            Details : ExoPTEN comprises exosomes loaded with siRNA that inhibits the production of the PTEN protein. It is being evaluated in preclinical studies for the treatment of acute spinal cord injury.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            March 14, 2025

                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            NurExone Biologic

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                            BIOHK2025
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                            NurExone Biologic

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                            Lead Product(s) : Exosome

                            Therapeutic Area : Ophthalmology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NurExone Shows Preclinical Results Restoring Vision After Optic Nerve Injury

                            Details : ExoPTEN comprises exosomes loaded with siRNA that inhibits the production of the PTEN protein. It is being evaluated in preclinical studies for the treatment of acute spinal cord injury.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            December 06, 2024

                            Lead Product(s) : Exosome

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            NurExone Biologic

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                            BIOHK2025
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                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NurExone Biologic Secures EMA Orphan Status for ExoPTEN in SCI

                            Details : ExoPTEN comprises exosomes loaded with siRNA that inhibits the production of the PTEN protein. It is being evaluated in preclinical studies for the treatment of acute spinal cord injury.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            November 13, 2024

                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            NurExone Biologic

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                            BIOHK2025
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                            Lead Product(s) : Exosome

                            Therapeutic Area : Ophthalmology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NurExone Shows Promising Results For ExoPTEN in Glaucoma Nerve Recovery Study

                            Details : ExoPTEN comprises exosomes loaded with siRNA that inhibits the production of the PTEN protein. It is being evaluated for glaucoma.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            July 17, 2024

                            Lead Product(s) : Exosome

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NurExone Shows Extended Window for ExoPTEN in Spinal Cord Injury Preclinical Study

                            Details : ExoPTEN comprises exosomes loaded with siRNA that inhibits the production of the PTEN protein. It is being evaluated in preclinical studies for the treatment of acute spinal cord injury.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            June 09, 2024

                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            NurExone Biologic

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                            BIOHK2025
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                            NurExone Biologic

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                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : $1.4 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            NurExone Closes Private Placement for Approximately CAD$2 Million

                            Details : The proceeds will focus on advancing ExoPTEN, targeted at acute Spinal Cord Injury, and developed using ExoTherapy Technology. These assets are progressing towards the clinical phase.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Undisclosed

                            May 01, 2024

                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : $1.4 million

                            Deal Type : Private Placement

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                            07

                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : $2.9 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Gross Proceeds Close of $4M CAD Generated for NurExone From Warrants Exercise

                            Details : The proceeds will focus on advancing ExoPTEN, targeted at acute Spinal Cord Injury, and developed using ExoTherapy Technology. These assets are progressing towards the clinical phase.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Undisclosed

                            March 27, 2024

                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : $2.9 million

                            Deal Type : Private Placement

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                            08

                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Recipient : Vivox

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            NurExone Signs Preclinical Testing Agreement for ExoPTEN Therapy

                            Details : Vivox will provide CRO services to NurExone to commence human trials, moving towards IND filing in the U.S. for ExoPTEN exosome-based therapy in spinal cord injury treatment.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Undisclosed

                            March 22, 2024

                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Recipient : Vivox

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            NurExone Biologic

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                            BIOHK2025
                            Not Confirmed
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                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nurexone Biologic Initiates European Orphan Drug Designation Process Following U.S. Grant

                            Details : ExoPTEN comprises exosomes loaded with small interfering RNA (siRNA) that inhibits the production of the PTEN protein. It is being evaluated in preclinical studies for acute spinal cord injury.

                            Product Name : ExoPTEN

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            February 02, 2024

                            Lead Product(s) : Exosome

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            NurExone Biologic

                            Israel arrow
                            BIOHK2025
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                            NurExone Biologic

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                            BIOHK2025
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Discovery Platform

                            Sponsor : Inteligex

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            NurExone and Inteligex Begin Research On Chronic Spinal Cord Injury

                            Details : The collaboration aims to combine Inteligex’s two decades of cell therapy expertise with NurExone’s exosome platform to treat chronic spinal cord injuries.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 17, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Discovery Platform

                            Sponsor : Inteligex

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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