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    [{"orgOrder":0,"company":"Numab Therapeutics","sponsor":"Numab Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody, Unconjugated","year":"2021","type":"Partnership","leadProduct":"ND021","moa":"4-1BB","graph1":"Oncology","graph2":"Preclinical","graph3":"Numab Therapeutics","amount2":0.02,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.02,"dosageForm":"Undisclosed","sponsorNew":"Numab Therapeutics \/ Numab Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Numab Therapeutics \/ Numab Therapeutics"},{"orgOrder":0,"company":"Numab Therapeutics","sponsor":"3S Bio Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Antibody, Unconjugated","year":"2020","type":"Series B Financing","leadProduct":"ND021","moa":"4-1BB","graph1":"Oncology","graph2":"IND Enabling","graph3":"Numab 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    Find Clinical Drug Pipeline Developments & Deals by Numab Therapeutics

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                            01

                            Numab Therapeutics

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                            Lead Product(s) : ND047

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Boehringer Ingelheim GmbH

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Numab Therapeutics Achieves Milestone in Collaboration with Boehringer Ingelheim

                            Details : Boehringer has advanced its novel T cell engager, ND047, for the treatment of lung and GI cancers resulting from a collaboration with Numab into preclinical development.

                            Product Name : ND047

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            September 25, 2025

                            Lead Product(s) : ND047

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Boehringer Ingelheim GmbH

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            02

                            Numab Therapeutics

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                            Numab Therapeutics

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                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Cormorant Asset Management

                            Deal Size : $197.6 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Numab Extends Series C to CHF 180M With CHF 50M Oversubscribed Financing

                            Details : The Proceeds will be used to support the advancement of multiple first-in-class and best-in-class programs into clinical development, which includes NM26-2198 is being evaluated for atopic dermatitis.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            January 09, 2025

                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Cormorant Asset Management

                            Deal Size : $197.6 million

                            Deal Type : Series C Financing

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                            03

                            Numab Therapeutics

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                            Lead Product(s) : ND081

                            Therapeutic Area : Gastroenterology

                            Study Phase : Preclinical

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Numab and Kaken Collaborate On ND081 for Inflammatory Bowel Disease

                            Details : The collaboration aims to develop ND081, a potential first-in-class multi-specific antibody for the treatment of inflammatory bowel disease (IBD).

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $14.6 million

                            November 15, 2024

                            Lead Product(s) : ND081

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Preclinical

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            Numab Therapeutics

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                            Numab Therapeutics

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                            Lead Product(s) : NM32-2668

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Numab Starts Phase 1 Study of NM32 in Solid Tumor Patients

                            Details : NM32 is a next generation tri-specific immuno-oncology drug targeting the ROR1 receptor & CD3. It is being evaluated for the treatment of solid tumors.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 30, 2024

                            Lead Product(s) : NM32-2668

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Numab Therapeutics

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                            Numab Therapeutics

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                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Johnson & Johnson

                            Deal Size : $1,250.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Johnson & Johnson Gains Rights to Clinical-Stage Bispecific Antibody for Atopic Dermatitis

                            Details : The agreement aims to acquire NM26, a Phase 2-ready investigational, first-in-class bispecific antibody targeting two clinically proven pathways in atopic dermatitis (AD).

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : $1,250.0 million

                            May 28, 2024

                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Johnson & Johnson

                            Deal Size : $1,250.0 million

                            Deal Type : Acquisition

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                            06

                            Numab Therapeutics

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                            Numab Therapeutics

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                            Lead Product(s) : NM32-2668

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NM32-2668 in Adult Patients With Selected Advanced Solid Tumors

                            Details : NM32-2668 is a Other Large Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Ovarian Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 07, 2024

                            Lead Product(s) : NM32-2668

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Numab Therapeutics

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                            Numab Therapeutics

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                            Lead Product(s) : NM49

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Ono Pharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Numab and Ono Announce Collaboration Agreement for NM49 Cancer Treatment

                            Details : Ono obtained rights for NM49 from Numab for global development and commercialization. NM49 is a multi-specific antibody designed to activate tumor-associated macrophage phagocytosis for cancer.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            February 14, 2024

                            Lead Product(s) : NM49

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Ono Pharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Numab Therapeutics

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                            Numab Therapeutics

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                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Numab Therapeutics Announces First Patient Dosed in Phase 1 Multiple Ascending Dose (MAD) Study of NM26 for Mo...

                            Details : NM26/NM26-2198, a first-in-class bi-specific antibody for the treatment of moderate-to-severe atopic dermatitis (AD). MAD data expected to be reported in mid-2024; Single ascending dose (SAD) cohort in healthy volunteers remains ongoing.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            October 19, 2023

                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Numab Therapeutics

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                            Numab Therapeutics

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                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Numab Therapeutics Announces First Subject Dosed in Phase 1 Clinical Study of NM26 Program

                            Details : NM26-2198 is a bi-specific antibody which targets IL-4Rα (type I and type II receptors) and IL-31 for the treatment of moderate-to-severe atopic dermatitis (AD).

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            May 15, 2023

                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Numab Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Sponsor : Ono Pharmaceutical

                            Deal Size : $276.6 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Numab Therapeutics and Ono Pharmaceutical Enter Development and License Agreement for Multispecific Antibody C...

                            Details : Under the terms of the license agreement, Ono acquires intellectual property rights and exclusive global development and commercialization rights for a multispecific antibody targeting a novel immuno-oncology target.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            March 31, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Sponsor : Ono Pharmaceutical

                            Deal Size : $276.6 million

                            Deal Type : Licensing Agreement

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