Lead Product(s) : Voclosporin,Mycophenolate Mofetil,Undisclosed
Therapeutic Area : Nephrology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Lupkynis (voclosporin) is a calcineurin-inhibitor of calcineurin. The immunosuppressant activity results in inhibition of lymphocyte proliferation, T-cell cytokine production, and expression of T-cell activation surface antigens. Currently being develope...
Product Name : Lupkynis
Product Type : Peptide
Upfront Cash : Inapplicable
November 04, 2023
Lead Product(s) : Voclosporin,Mycophenolate Mofetil,Undisclosed
Therapeutic Area : Nephrology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Repirinast
Therapeutic Area : Nephrology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NP-251 (repirinast), company’s lead candidate for the treatment of chronic kidney disease, binds to receptors on mast cell and prevents their degranulation. Repirinast originally developed by Mitsubishi was sold in Japan under the brand name Romet™ f...
Product Name : NP-251
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 31, 2023
Lead Product(s) : Repirinast
Therapeutic Area : Nephrology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Voclosporin,Mycophenolate Mofetil,Undisclosed
Therapeutic Area : Nephrology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Lupkynis (voclosporin) is a calcineurin-inhibitor of calcineurin. The immunosuppressant activity results in inhibition of lymphocyte proliferation, T-cell cytokine production, and expression of T-cell activation surface antigens. Currently being develope...
Product Name : Lupkynis
Product Type : Peptide
Upfront Cash : Inapplicable
January 24, 2023
Lead Product(s) : Voclosporin,Mycophenolate Mofetil,Undisclosed
Therapeutic Area : Nephrology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Repirinast
Therapeutic Area : Nephrology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In pre-clinical model of kidney fibrosis, NP-251 (repirinast) reduced fibrosis by 50% with statistical significance, showed improvement when given in combination with Telmisartan, which is BP lowering medication and is considered, standard of care treatm...
Product Name : NP-251
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 07, 2022
Lead Product(s) : Repirinast
Therapeutic Area : Nephrology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Repirinast
Therapeutic Area : Nephrology
Study Phase : Preclinical
Sponsor : Zhejiang Ausun Pharmaceutical
Deal Size : Undisclosed
Deal Type : Agreement
Details : Repirinast was originally developed by Mitsubishi Tanabe Pharma (“Mitsubishi”) and was sold and marketed in Japan under the brand name Romet™ for the treatment of asthma. Romet™ was marketed for over 25 years in Japan.
Product Name : NP-251
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 23, 2022
Lead Product(s) : Repirinast
Therapeutic Area : Nephrology
Highest Development Status : Preclinical
Sponsor : Zhejiang Ausun Pharmaceutical
Deal Size : Undisclosed
Deal Type : Agreement