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    [{"orgOrder":0,"company":"National Institute of Allergy and Infectious Diseases","sponsor":"Eli Lilly","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Agreement","leadProduct":"Baricitinib","moa":"JAK1\/JAK2","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed","graph3":"National Institute of Allergy and Infectious Diseases","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"National Institute of Allergy and Infectious Diseases \/ Eli Lilly","highestDevelopmentStatusID":"1","companyTruncated":"National Institute of Allergy and Infectious Diseases \/ Eli Lilly"},{"orgOrder":0,"company":"National Institute of Allergy and Infectious Diseases","sponsor":"Regeneron Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious 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    Find Clinical Drug Pipeline Developments & Deals by National Institute of Allergy and Infectious Diseases

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                            01

                            National Institute of Allergy and Infectious Diseases

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                            National Institute of Allergy and Infectious Diseases

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                            Lead Product(s) : AGENT-797

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Recipient : MiNK Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            MiNK Awarded Prestigious NIAID Grant to Advance Allo-iNKT Cell Therapy

                            Details : The grant will support development of MiNK’s allo-iNKT cell therapy, AGENT-797, for the prevention and treatment of graft-versus-host disease (GvHD) following hematopoietic stem cell transplantation.

                            Product Name : AGENT-797

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            June 02, 2025

                            Lead Product(s) : AGENT-797

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Recipient : MiNK Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            02

                            National Institute of Allergy and Infectious Diseases

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                            AGGSpend
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                            National Institute of Allergy and Infectious Diseases

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                            AGGSpend
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                            Lead Product(s) : H1ssF-3928 mRNA-LNP

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Clinical Trial of mRNA Universal Influenza Vaccine Candidate Begins

                            Details : H1ssF-3928 mRNA-LNP (based on mRNA platform), is an influenza vaccine, which is being investigated for safety and its ability to induce a strong and broad immunity against a variety of strains.

                            Product Name : H1ssF_3928

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            May 15, 2023

                            Lead Product(s) : H1ssF-3928 mRNA-LNP

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            National Institute of Allergy and Infectious Diseases

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                            AGGSpend
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                            National Institute of Allergy and Infectious Diseases

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                            AGGSpend
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                            Lead Product(s) : Hepatitis B Vaccine Recombinant, Adjuvanted

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Dynavax Technologies

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Three-dose Hepatitis B Vaccine Regimen Protects People With HIV

                            Details : HEPLISAV-B [Hepatitis B Vaccine (Recombinant), Adjuvanted] Solution for Intramuscular Injection,B is indicated for prevention of infection caused by all known subtypes of hepatitis B virus.

                            Product Name : Heplisav-B

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            October 22, 2022

                            Lead Product(s) : Hepatitis B Vaccine Recombinant, Adjuvanted

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Dynavax Technologies

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            National Institute of Allergy and Infectious Diseases

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                            Lead Product(s) : Casirivimab,REGN10987

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Regeneron Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            National Institute of Allergy and Infectious Diseases Started Enrolling in Clinical Trials Of Monoclonal Antib...

                            Details : Two Phase 3, randomized, placebo-controlled, double-blind clinical trials testing whether experimental monoclonal antibodies (mAbs) can prevent infection by SARS-CoV-2 coronavirus are now enrolling healthy adults at clinical trial sites in the United Sta...

                            Product Name : REGN-COV2

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            October 08, 2020

                            Lead Product(s) : Casirivimab,REGN10987

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Regeneron Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            National Institute of Allergy and Infectious Diseases

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                            AGGSpend
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                            National Institute of Allergy and Infectious Diseases

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                            Lead Product(s) : Baricitinib

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Undisclosed

                            Sponsor : Eli Lilly

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Lilly Begins Clinical Testing of Therapies for COVID-19

                            Details : The study will investigate the efficacy and safety of baricitinib as a potential treatment for hospitalized patients diagnosed with COVID-19.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 04, 2020

                            Lead Product(s) : Baricitinib

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Undisclosed

                            Sponsor : Eli Lilly

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            National Institute of Allergy and Infectious Diseases

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                            AGGSpend
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                            National Institute of Allergy and Infectious Diseases

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                            Lead Product(s) : Cabotegravir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            HIV Prevention Trials Network Finds Cabotegravir Linked With Prevention of HIV Infection in Cisgender Men and ...

                            Details : The study showed that CAB LA lowered HIV incidence among cisgender men and transgender women who have sex with men.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 18, 2020

                            Lead Product(s) : Cabotegravir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            National Institute of Allergy and Infectious Diseases

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                            AGGSpend
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                            Lead Product(s) : VRC07-523LS,Cabotegravir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : ViiV Healthcare

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            1st clinical trial kicks off to test antibody-drug combination for HIV treatment

                            Details : The Phase 2 trial will also test whether the combination could prevent HIV from rebounding to detectable levels in people who previously kept the virus suppressed with daily antiretroviral therapy.

                            Product Name : VRC07-523LS

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 27, 2020

                            Lead Product(s) : VRC07-523LS,Cabotegravir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : ViiV Healthcare

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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